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Jayajit Das
Jayajit Das
Nationwide Childrens Hospital and The Ohio State University
在 nationwidechildrens.org 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Digital signaling and hysteresis characterize ras activation in lymphoid cells
J Das, M Ho, J Zikherman, C Govern, M Yang, A Weiss, AK Chakraborty, ...
Cell 136 (2), 337-351, 2009
4792009
Role of nanoscale antigen organization on B-cell activation probed using DNA origami
R Veneziano, TJ Moyer, MB Stone, EC Wamhoff, BJ Read, S Mukherjee, ...
Nature nanotechnology 15 (8), 716-723, 2020
3072020
The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality
S Čemerski, J Das, E Giurisato, MA Markiewicz, PM Allen, ...
Immunity 29 (3), 414-422, 2008
1672008
Purely stochastic binary decisions in cell signaling models without underlying deterministic bistabilities
MN Artyomov, J Das, M Kardar, AK Chakraborty
Proceedings of the National Academy of Sciences 104 (48), 18958-18963, 2007
1212007
The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse
S Čemerski, J Das, J Locasale, P Arnold, E Giurisato, MA Markiewicz, ...
Immunity 26 (3), 345-355, 2007
1182007
Monovalent and multivalent ligation of the B cell receptor exhibit differential dependence upon Syk and Src family kinases
S Mukherjee, J Zhu, J Zikherman, R Parameswaran, TA Kadlecek, ...
Science signaling 6 (256), ra1-ra1, 2013
852013
Decreased diacylglycerol metabolism enhances ERK activation and augments CD8+ T cell functional responses
MJ Riese, J Grewal, J Das, T Zou, V Patil, AK Chakraborty, GA Koretzky
Journal of biological chemistry 286 (7), 5254-5265, 2011
772011
Origin of the sharp boundary that discriminates positive and negative selection of thymocytes
A Prasad, J Zikherman, J Das, JP Roose, A Weiss, AK Chakraborty
Proceedings of the National Academy of Sciences 106 (2), 528-533, 2009
762009
Pairing computation with experimentation: a powerful coupling for understanding T cell signalling
AK Chakraborty, J Das
Nature Reviews Immunology 10 (1), 59-71, 2010
692010
The ζ isoform of diacylglycerol kinase plays a predominant role in regulatory T cell development and TCR-mediated ras signaling
RP Joshi, AM Schmidt, J Das, D Pytel, MJ Riese, M Lester, JA Diehl, ...
Science signaling 6 (303), ra102-ra102, 2013
642013
Sensitivity of T cells to antigen and antagonism emerges from differential regulation of the same molecular signaling module
DC Wylie, J Das, AK Chakraborty
Proceedings of the National Academy of Sciences 104 (13), 5533-5538, 2007
642007
NK cells: tuned by peptide?
J Das, SI Khakoo
Immunological reviews 267 (1), 214-227, 2015
482015
A dendronized polymer is a single-molecule glass
J Das, M Yoshida, ZM Fresco, TL Choi, JMJ Fréchet, AK Chakraborty
The Journal of Physical Chemistry B 109 (14), 6535-6543, 2005
402005
Positive feedback regulation results in spatial clustering and fast spreading of active signaling molecules on a cell membrane
J Das, M Kardar, AK Chakraborty
The Journal of Chemical Physics 130 (24), 2009
392009
Effect of cross-linking on the structure and thermodynamics of lamellar block copolymers
ED Gomez, J Das, AK Chakraborty, JA Pople, NP Balsara
Macromolecules 39 (14), 4848-4859, 2006
392006
Extracellular DNA and Type IV Pilus Expression Regulate the Structure and Kinetics of Biofilm Formation by Nontypeable Haemophilus influenzae
J Das, E Mokrzan, V Lakhani, L Rosas, JA Jurcisek, WC Ray, LO Bakaletz
MBio 8 (6), 10.1128/mbio. 01466-17, 2017
372017
Activation or tolerance of natural killer cells is modulated by ligand quality in a nonmonotonic manner
J Das
Biophysical journal 99 (7), 2028-2037, 2010
342010
Peptide selectivity discriminates NK cells from KIR2DL2‐and KIR2DL3‐positive individuals
S Cassidy, S Mukherjee, TM Myint, B Mbiribindi, H North, J Traherne, ...
European journal of immunology 45 (2), 492-500, 2015
322015
In silico modeling identifies CD45 as a regulator of IL-2 synergy in the NKG2D-mediated activation of immature human NK cells
S Mukherjee, H Jensen, W Stewart, D Stewart, WC Ray, SY Chen, ...
Science signaling 10 (485), eaai9062, 2017
302017
Molecular origin and functional consequences of digital signaling and hysteresis during Ras activation in lymphocytes
AK Chakraborty, J Das, J Zikherman, M Yang, CC Govern, M Ho, A Weiss, ...
Science signaling 2 (66), pt2-pt2, 2009
302009
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