Expression of A53T mutant but not wild-type α-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and … L Stefanis, KE Larsen, HJ Rideout, D Sulzer, LA Greene Journal of Neuroscience 21 (24), 9549-9560, 2001 | 742 | 2001 |
Pathological roles of α-synuclein in neurological disorders K Vekrellis, M Xilouri, E Emmanouilidou, HJ Rideout, L Stefanis The Lancet Neurology 10 (11), 1015-1025, 2011 | 458 | 2011 |
Proteasomal inhibition leads to formation of ubiquitin/α‐synuclein‐immunoreactive inclusions in PC12 cells HJ Rideout, KE Larsen, D Sulzer, L Stefanis Journal of neurochemistry 78 (4), 899-908, 2001 | 378 | 2001 |
Involvement of macroautophagy in the dissolution of neuronal inclusions HJ Rideout, I Lang-Rollin, L Stefanis The international journal of biochemistry & cell biology 36 (12), 2551-2562, 2004 | 222 | 2004 |
LRRK2 Parkinson disease mutations enhance its microtubule association LR Kett, D Boassa, CCY Ho, HJ Rideout, J Hu, M Terada, M Ellisman, ... Human molecular genetics 21 (4), 890-899, 2011 | 208 | 2011 |
The Parkinson disease protein leucine-rich repeat kinase 2 transduces death signals via Fas-associated protein with death domain and caspase-8 in a cellular model of … CCY Ho, HJ Rideout, E Ribe, CM Troy, WT Dauer Journal of Neuroscience 29 (4), 1011-1016, 2009 | 199 | 2009 |
Proteasome inhibition and Parkinson's disease modeling J Bové, C Zhou, V Jackson‐Lewis, J Taylor, Y Chu, HJ Rideout, DC Wu, ... Annals of Neurology: Official Journal of the American Neurological …, 2006 | 169 | 2006 |
Proteasomal inhibition-induced inclusion formation and death in cortical neurons require transcription and ubiquitination HJ Rideout, L Stefanis Molecular and Cellular Neuroscience 21 (2), 223-238, 2002 | 157 | 2002 |
Neurobiology of α-synuclein K Vekrellis, HJ Rideout, L Stefanis Molecular neurobiology 30, 1-21, 2004 | 137 | 2004 |
The WD40 domain is required for LRRK2 neurotoxicity ND Jorgensen, Y Peng, CCY Ho, HJ Rideout, D Petrey, P Liu, WT Dauer PloS one 4 (12), e8463, 2009 | 134 | 2009 |
Cyclin-dependent kinase activity is required for apoptotic death but not inclusion formation in cortical neurons after proteasomal inhibition HJ Rideout, Q Wang, DS Park, L Stefanis Journal of Neuroscience 23 (4), 1237-1245, 2003 | 131 | 2003 |
Cyclin-dependent kinases and P53 pathways are activated independently and mediate Bax activation in neurons after DNA damage EJ Morris, E Keramaris, HJ Rideout, RS Slack, NJ Dyson, L Stefanis, ... Journal of Neuroscience 21 (14), 5017-5026, 2001 | 131 | 2001 |
Mechanisms of caspase-independent neuronal death: energy depletion and free radical generation ICJ Lang-Rollin, HJ Rideout, M Noticewala, L Stefanis Journal of Neuroscience 23 (35), 11015-11025, 2003 | 129 | 2003 |
Dopaminergic neurons in rat ventral midbrain cultures undergo selective apoptosis and form inclusions, but do not up‐regulate iHSP70, following proteasomal inhibition HJ Rideout, ICJ Lang‐Rollin, M Savalle, L Stefanis Journal of neurochemistry 93 (5), 1304-1313, 2005 | 103 | 2005 |
The neurobiology of LRRK2 and its role in the pathogenesis of Parkinson’s disease HJ Rideout, L Stefanis Neurochemical research 39, 576-592, 2014 | 81 | 2014 |
Nurr1: RXRα heterodimer activation as monotherapy for Parkinson’s disease AD Spathis, X Asvos, D Ziavra, T Karampelas, S Topouzis, Z Cournia, ... Proceedings of the National Academy of Sciences 114 (15), 3999-4004, 2017 | 80 | 2017 |
Synuclein‐1 is selectively up‐regulated in response to nerve growth factor treatment in PC12 cells L Stefanis, N Kholodilov, HJ Rideout, RE Burke, LA Greene Journal of neurochemistry 76 (4), 1165-1176, 2001 | 80 | 2001 |
Caspase inhibition: a potential therapeutic strategy in neurological diseases L Stefanis, HJ Rideout Histology and Histopathology 16 (3), 895-908, 0 | 78* | |
Is spinal muscular atrophy a disease of the motor neurons only: pathogenesis and therapeutic implications? C Simone, A Ramirez, M Bucchia, P Rinchetti, H Rideout, D Papadimitriou, ... Cellular and molecular life sciences 73, 1003-1020, 2016 | 75 | 2016 |
Morphine enhancement of sucrose palatability: analysis by the taste reactivity test HJ Rideout, LA Parker Pharmacology Biochemistry and Behavior 53 (3), 731-734, 1996 | 64 | 1996 |