Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers H Li, KB Chiappinelli, AA Guzzetta, H Easwaran, RWC Yen, R Vatapalli, ... Oncotarget 5 (3), 587, 2014 | 437 | 2014 |
Small-molecule MYC inhibitors suppress tumor growth and enhance immunotherapy H Han, AD Jain, MI Truica, J Izquierdo-Ferrer, JF Anker, B Lysy, V Sagar, ... Cancer cell 36 (5), 483-497. e15, 2019 | 301 | 2019 |
Inhibiting DNA methylation activates cancer testis antigens and expression of the antigen processing and presentation machinery in colon and ovarian cancer cells C Siebenkäs, KB Chiappinelli, AA Guzzetta, A Sharma, J Jeschke, ... PLoS One 12 (6), e0179501, 2017 | 94 | 2017 |
Frequent inactivation of cysteine dioxygenase type 1 contributes to survival of breast cancer cells and resistance to anthracyclines J Jeschke, HM O'Hagan, W Zhang, R Vatapalli, MF Calmon, L Danilova, ... Clinical Cancer Research 19 (12), 3201-3211, 2013 | 94 | 2013 |
Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer R Vatapalli, V Sagar, Y Rodriguez, JC Zhao, K Unno, S Pamarthy, B Lysy, ... Nature communications 11 (1), 4153, 2020 | 81 | 2020 |
EPHB4 inhibition activates ER stress to promote immunogenic cell death of prostate cancer cells V Sagar, R Vatapalli, B Lysy, S Pamarthy, JF Anker, Y Rodriguez, H Han, ... Cell death & disease 10 (11), 801, 2019 | 45 | 2019 |
Dose-dependent activation of putative oncogene SBSN by BORIS D Gaykalova, R Vatapalli, CA Glazer, S Bhan, C Shao, D Sidransky, ... PloS one 7 (7), e40389, 2012 | 42 | 2012 |
Outlier analysis defines zinc finger gene family DNA methylation in tumors and saliva of head and neck cancer patients DA Gaykalova, R Vatapalli, Y Wei, HL Tsai, H Wang, C Zhang, ... PloS one 10 (11), e0142148, 2015 | 41 | 2015 |
Hypomethylating agents synergize with irinotecan to improve response to chemotherapy in colorectal cancer cells A Sharma, R Vatapalli, E Abdelfatah, K Wyatt McMahon, Z Kerner, ... PloS one 12 (4), e0176139, 2017 | 35 | 2017 |
Activated ALK cooperates with N-Myc via Wnt/β-catenin signaling to induce neuroendocrine prostate cancer K Unno, ZR Chalmers, S Pamarthy, R Vatapalli, Y Rodriguez, B Lysy, ... Cancer research 81 (8), 2157-2170, 2021 | 34 | 2021 |
The role of castration-resistant Bmi1+ Sox2+ cells in driving recurrence in prostate cancer YA Yoo, R Vatapalli, B Lysy, H Mok, MM Desouki, SA Abdulkadir JNCI: Journal of the National Cancer Institute 111 (3), 311-321, 2019 | 32 | 2019 |
Integrative computational analysis of transcriptional and epigenetic alterations implicates DTX1 as a putative tumor suppressor gene in HNSCC DA Gaykalova, V Zizkova, T Guo, I Tiscareno, Y Wei, R Vatapalli, ... Oncotarget 8 (9), 15349, 2017 | 19 | 2017 |
KRAS G> A mutation favors poor tumor differentiation but may not be associated with prognosis in patients with curatively resected duodenal adenocarcinoma T Fu, AA Guzzetta, J Jeschke, R Vatapalli, P Dave, CM Hooker, R Morgan, ... International journal of cancer 132 (11), 2502-2509, 2013 | 17 | 2013 |
A genome-wide CRISPR activation screen identifies PRRX2 as a regulator of enzalutamide resistance in prostate cancer Y Rodríguez, K Unno, MI Truica, ZR Chalmers, YA Yoo, R Vatapalli, ... Cancer research 82 (11), 2110-2123, 2022 | 12 | 2022 |
CpG island methylator phenotype and its association with malignancy in sporadic duodenal adenomas L Sun, AA Guzzetta, T Fu, J Chen, J Jeschke, R Kwak, R Vatapalli, ... Epigenetics 9 (5), 738-746, 2014 | 11 | 2014 |
Inflammatory bowel disease induces inflammatory and pre-neoplastic changes in the prostate AS Desai, V Sagar, B Lysy, AB Weiner, OS Ko, C Driscoll, Y Rodriguez, ... Prostate cancer and prostatic diseases 25 (3), 463-471, 2022 | 9 | 2022 |
Organoids Increase the Predictive Value of in vitro Cancer Chemoprevention Studies for in vivo Outcome RN Njoroge, RJ Vatapalli, SA Abdulkadir Frontiers in Oncology 9, 77, 2019 | 7 | 2019 |
A Guzzetta A, Singh J, Zahnow C, B Baylin S, Yerram S, Hu Y, Azad N, Ahuja N. Hypomethylating agents synergize with irinotecan to improve response to chemotherapy in colorectal … A Sharma, R Vatapalli, E Abdelfatah, K Wyatt McMahon, Z Kerner PLoS One 12, e0176139, 2017 | 4 | 2017 |
Improving sensitivity to irinotecan using 5-azacytidine in colon cancer cell lines RJ Vatapalli, AA Guzzetta, T Fu, LH Syed, R Kwak, N Ahuja Journal of Surgical Research 179 (2), 251-252, 2013 | 4 | 2013 |
combining anti-androgen therapy and PARP inhibition results in synergistic cytotoxicity of metastatic castration-resistant prostate cancer (mCRPC) cells S Pamarthy, V Sagar, RJ Vatapalli, Z Reinstein, MZ Ansari, BAC Filho, ... Cancer Research 77 (13_Supplement), 1114-1114, 2017 | 1 | 2017 |