Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy, 1-382, 2021 | 13234* | 2021 |
Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex C Ciferri, S Pasqualato, E Screpanti, G Varetti, S Santaguida, G Dos Reis, ... Cell 133 (3), 427-439, 2008 | 634 | 2008 |
The life and miracles of kinetochores S Santaguida, A Musacchio The EMBO journal 28 (17), 2511-2531, 2009 | 588 | 2009 |
Short-and long-term effects of chromosome mis-segregation and aneuploidy S Santaguida, A Amon Nature reviews Molecular cell biology 16 (8), 473-485, 2015 | 560 | 2015 |
Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine S Santaguida, A Tighe, AM D'Alise, SS Taylor, A Musacchio Journal of Cell Biology 190 (1), 73-87, 2010 | 560 | 2010 |
Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1–C-Mad2 core complex L Hewitt, A Tighe, S Santaguida, AM White, CD Jones, A Musacchio, ... Journal of Cell Biology 190 (1), 25-34, 2010 | 368 | 2010 |
Chromosome mis-segregation generates cell-cycle-arrested cells with complex karyotypes that are eliminated by the immune system S Santaguida, A Richardson, DR Iyer, O M'Saad, L Zasadil, KA Knouse, ... Developmental cell 41 (6), 638-651. e5, 2017 | 342 | 2017 |
The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint M Mapelli, L Massimiliano, S Santaguida, A Musacchio Cell 131 (4), 730-743, 2007 | 284 | 2007 |
The MIS12 complex is a protein interaction hub for outer kinetochore assembly A Petrovic, S Pasqualato, P Dube, V Krenn, S Santaguida, D Cittaro, ... Journal of Cell Biology 190 (5), 835-852, 2010 | 275 | 2010 |
Side by side comparison between dynamic versus static models of blood–brain barrier in vitro: a permeability study S Santaguida, D Janigro, M Hossain, E Oby, E Rapp, L Cucullo Brain research 1109 (1), 1-13, 2006 | 248 | 2006 |
Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction S Santaguida, C Vernieri, F Villa, A Ciliberto, A Musacchio The EMBO journal 30 (8), 1508-1519, 2011 | 243 | 2011 |
Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition Y Cohen-Sharir, JM McFarland, M Abdusamad, C Marquis, SV Bernhard, ... Nature 590 (7846), 486-491, 2021 | 171 | 2021 |
Aneuploidy-induced cellular stresses limit autophagic degradation S Santaguida, E Vasile, E White, A Amon Genes & development 29 (19), 2010-2021, 2015 | 165 | 2015 |
Structural analysis reveals features of the spindle checkpoint kinase Bub1–kinetochore subunit Knl1 interaction V Krenn, A Wehenkel, X Li, S Santaguida, A Musacchio Journal of Cell Biology 196 (4), 451-467, 2012 | 159 | 2012 |
Homeostatic control of mitotic arrest G Varetti, C Guida, S Santaguida, E Chiroli, A Musacchio Molecular cell 44 (5), 710-720, 2011 | 122 | 2011 |
A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B A De Antoni, S Maffini, S Knapp, A Musacchio, S Santaguida Journal of Cell Biology 199 (2), 269-284, 2012 | 114 | 2012 |
Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy MR Ippolito, V Martis, S Martin, AE Tijhuis, C Hong, R Wardenaar, ... Developmental cell 56 (17), 2440-2454. e6, 2021 | 109 | 2021 |
Protein aggregation mediates stoichiometry of protein complexes in aneuploid cells CM Brennan, LP Vaites, JN Wells, S Santaguida, JA Paulo, Z Storchova, ... Genes & development 33 (15-16), 1031-1047, 2019 | 98 | 2019 |
Crystal structure of human aurora B in complex with INCENP and VX-680 JM Elkins, S Santaguida, A Musacchio, S Knapp Journal of medicinal chemistry 55 (17), 7841-7848, 2012 | 94 | 2012 |
Structural analysis of the RZZ complex reveals common ancestry with multisubunit vesicle tethering machinery F Çivril, A Wehenkel, FM Giorgi, S Santaguida, A Di Fonzo, G Grigorean, ... Structure 18 (5), 616-626, 2010 | 94 | 2010 |