| HIFα targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing M Ivan, K Kondo, H Yang, W Kim, J Valiando, M Ohh, A Salic, JM Asara, ... Science 292 (5516), 464-468, 2001 | 5863 | 2001 |
| Comprehensive molecular characterization of urothelial bladder carcinoma Cancer Genome Atlas Research Network Nature 507 (7492), 315, 2014 | 2654 | 2014 |
| Role of VHL Gene Mutation in Human Cancer WY Kim, WG Kaelin Journal of clinical oncology 22 (24), 4991-5004, 2004 | 1228 | 2004 |
| The regulation of INK4/ARF in cancer and aging WY Kim, NE Sharpless Cell 127 (2), 265-275, 2006 | 1225 | 2006 |
| A consensus molecular classification of muscle-invasive bladder cancer A Kamoun, A de Reynies, Y Allory, G Sjödahl, AG Robertson, R Seiler, ... European urology 77 (4), 420-433, 2020 | 982 | 2020 |
| Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology JS Damrauer, KA Hoadley, DD Chism, C Fan, CJ Tiganelli, SE Wobker, ... Proceedings of the national academy of sciences 111 (8), 3110-3115, 2014 | 914 | 2014 |
| The cancer genome atlas comprehensive molecular characterization of renal cell carcinoma CJ Ricketts, AA De Cubas, H Fan, CC Smith, M Lang, E Reznik, R Bowlby, ... Cell reports 23 (1), 313-326. e5, 2018 | 838 | 2018 |
| Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer JS Duncan, MC Whittle, K Nakamura, AN Abell, AA Midland, ... Cell 149 (2), 307-321, 2012 | 835 | 2012 |
| Impact of molecular subtypes in muscle-invasive bladder cancer on predicting response and survival after neoadjuvant chemotherapy R Seiler, HAD Ashab, N Erho, BWG van Rhijn, B Winters, J Douglas, ... European urology 72 (4), 544-554, 2017 | 762 | 2017 |
| Inhibition of HIF2α is sufficient to suppress pVHL-defective tumor growth K Kondo, WY Kim, M Lechpammer, WG Kaelin Jr PLoS biology 1 (3), e83, 2003 | 717 | 2003 |
| The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies H Ji, D Li, L Chen, T Shimamura, S Kobayashi, K McNamara, U Mahmood, ... Cancer cell 9 (6), 485-495, 2006 | 537 | 2006 |
| Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: assessment of an oral agent that stimulates erythropoietin production M Safran, WY Kim, F O'Connell, L Flippin, V Günzler, JW Horner, ... Proceedings of the National Academy of Sciences 103 (1), 105-110, 2006 | 365 | 2006 |
| Interleukin-6: a candidate mediator of human prostate cancer morbidity DA Twillie, MA Eisenberger, MA Carducci, WS Hseih, WY Kim, ... Urology 45 (3), 542-549, 1995 | 363 | 1995 |
| VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and snail AJ Evans, RC Russell, O Roche, TN Burry, JE Fish, VWK Chow, WY Kim, ... Molecular and cellular biology 27 (1), 157-169, 2007 | 332 | 2007 |
| Coexistent ARID1A–PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling RL Chandler, JS Damrauer, JR Raab, JC Schisler, MD Wilkerson, ... Nature communications 6 (1), 6118, 2015 | 321 | 2015 |
| Failure to prolyl hydroxylate hypoxia‐inducible factor α phenocopies VHL inactivation in vivo WY Kim, M Safran, MRM Buckley, BL Ebert, J Glickman, M Bosenberg, ... The EMBO journal 25 (19), 4650-4662, 2006 | 277 | 2006 |
| Integrative genomic and proteomic analyses identify targets for Lkb1-deficient metastatic lung tumors J Carretero, T Shimamura, K Rikova, AL Jackson, MD Wilkerson, ... Cancer cell 17 (6), 547-559, 2010 | 258 | 2010 |
| Endogenous retroviral signatures predict immunotherapy response in clear cell renal cell carcinoma CC Smith, KE Beckermann, DS Bortone, AA De Cubas, LM Bixby, SJ Lee, ... The Journal of clinical investigation 128 (11), 4804-4820, 2019 | 245 | 2019 |
| Neoadjuvant clinical trial with sorafenib for patients with stage II or higher renal cell carcinoma CL Cowey, C Amin, RS Pruthi, EM Wallen, ME Nielsen, G Grigson, ... Journal of Clinical Oncology 28 (9), 1502-1507, 2010 | 244 | 2010 |
| The von Hippel–Lindau tumor suppressor protein: new insights into oxygen sensing and cancer W Kim, WG Kaelin Jr Current opinion in genetics & development 13 (1), 55-60, 2003 | 230 | 2003 |
