Detecting repeated cancer evolution from multi-region tumor sequencing data G Caravagna, Y Giarratano, D Ramazzotti, I Tomlinson, TA Graham, ... Nature methods 15 (9), 707-714, 2018 | 169 | 2018 |
Subclonal reconstruction of tumors by using machine learning and population genetics G Caravagna, T Heide, MJ Williams, L Zapata, D Nichol, K Chkhaidze, ... Nature genetics 52 (9), 898-907, 2020 | 104 | 2020 |
CAPRI: efficient inference of cancer progression models from cross-sectional data D Ramazzotti, G Caravagna, L Olde Loohuis, A Graudenzi, I Korsunsky, ... Bioinformatics 31 (18), 3016-3026, 2015 | 100 | 2015 |
Exploiting evolutionary steering to induce collateral drug sensitivity in cancer A Acar, D Nichol, J Fernandez-Mateos, GD Cresswell, I Barozzi, SP Hong, ... Nature communications 11 (1), 1923, 2020 | 95 | 2020 |
Algorithmic methods to infer the evolutionary trajectories in cancer progression G Caravagna, A Graudenzi, D Ramazzotti, R Sanz-Pamplona, L De Sano, ... PNAS 113 (28), E4025–E4034, 2016 | 93 | 2016 |
Phenotypic plasticity and genetic control in colorectal cancer evolution J Househam, T Heide, GD Cresswell, I Spiteri, C Kimberley, L Zapata, ... Nature 611 (7937), 744-753, 2022 | 84 | 2022 |
Chromatin Velocity reveals epigenetic dynamics by single-cell profiling of heterochromatin and euchromatin M Tedesco, F Giannese, D Lazarević, V Giansanti, D Rosano, S Monzani, ... Nature biotechnology 40 (2), 235-244, 2022 | 74 | 2022 |
Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data K Chkhaidze, T Heide, B Werner, MJ Williams, W Huang, G Caravagna, ... PLoS computational biology 15 (7), e1007243, 2019 | 73 | 2019 |
Inferring tree causal models of cancer progression with probability raising LO Loohuis, G Caravagna, A Graudenzi, D Ramazzotti, G Mauri, ... PloS one 9 (10), e108358, 2014 | 73 | 2014 |
Tumour suppression by immune system through stochastic oscillations G Caravagna, A d’Onofrio, P Milazzo, R Barbuti Journal of theoretical biology 265 (3), 336-345, 2010 | 72* | 2010 |
Evolutionary dynamics of residual disease in human glioblastoma I Spiteri, G Caravagna, GD Cresswell, A Vatsiou, D Nichol, A Acar, ... Annals of Oncology 30 (3), 456-463, 2019 | 70 | 2019 |
The co-evolution of the genome and epigenome in colorectal cancer T Heide, J Househam, GD Cresswell, I Spiteri, C Lynn, M Mossner, ... Nature 611 (7937), 733-743, 2022 | 62 | 2022 |
TRONCO: an R package for the inference of cancer progression models from heterogeneous genomic data L De Sano, G Caravagna, D Ramazzotti, A Graudenzi, G Mauri, B Mishra, ... Bioinformatics 32 (12), 1911-1913, 2016 | 47 | 2016 |
The interplay of intrinsic and extrinsic bounded noises in biomolecular networks G Caravagna, G Mauri, A d'Onofrio PLoS One 8 (2), e51174, 2013 | 47 | 2013 |
The calculus of looping sequences R Barbuti, G Caravagna, A Maggiolo–Schettini, P Milazzo, G Pardini Formal Methods for Computational Systems Biology: 8th International School …, 2008 | 47 | 2008 |
Signatures of TOP1 transcription-associated mutagenesis in cancer and germline MAM Reijns, DA Parry, TC Williams, F Nadeu, RL Hindshaw, ... Nature, 2022 | 42 | 2022 |
Learning mutational graphs of individual tumour evolution from single-cell and multi-region sequencing data D Ramazzotti, A Graudenzi, L De Sano, M Antoniotti, G Caravagna BMC bioinformatics 20, 1-13, 2019 | 38 | 2019 |
Germline MBD4 deficiency causes a multi-tumor predisposition syndrome C Palles, HD West, E Chew, S Galavotti, C Flensburg, JE Grolleman, ... The American Journal of Human Genetics 109 (5), 953-960, 2022 | 33* | 2022 |
Reply to ‘Neutral tumor evolution?’ T Heide, L Zapata, MJ Williams, B Werner, G Caravagna, CP Barnes, ... Nature genetics 50 (12), 1633-1637, 2018 | 32 | 2018 |
Investigating the relation between stochastic differentiation, homeostasis and clonal expansion in intestinal crypts via multiscale modeling A Graudenzi, G Caravagna, G De Matteis, M Antoniotti PLoS One 9 (5), e97272, 2014 | 29* | 2014 |