Uncovering molecular mechanisms involved in activation of G protein-coupled receptors U Gether Endocrine reviews 21 (1), 90-113, 2000 | 1697 | 2000 |
SLC6 neurotransmitter transporters: structure, function, and regulation AS Kristensen, J Andersen, TN Jørgensen, L Sørensen, J Eriksen, ... Pharmacological reviews 63 (3), 585-640, 2011 | 898 | 2011 |
G protein-coupled receptors: II. Mechanism of agonist activation U Gether, BK Kobilka Journal of Biological Chemistry 273 (29), 17979-17982, 1998 | 873 | 1998 |
Activation of the β2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6 JA Ballesteros, AD Jensen, G Liapakis, SGF Rasmussen, L Shi, U Gether, ... Journal of Biological Chemistry 276 (31), 29171-29177, 2001 | 823 | 2001 |
Correlation between genetic and geographic structure in Europe O Lao, TT Lu, M Nothnagel, O Junge, S Freitag-Wolf, A Caliebe, ... Current Biology 18 (16), 1241-1248, 2008 | 616 | 2008 |
Maltose–neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins PS Chae, SGF Rasmussen, RR Rana, K Gotfryd, R Chandra, MA Goren, ... Nature methods 7 (12), 1003-1008, 2010 | 526 | 2010 |
Agonists induce conformational changes in transmembrane domains III and VI of the β2 adrenoceptor U Gether, S Lin, P Ghanouni, JA Ballesteros, H Weinstein, BK Kobilka The EMBO journal, 1997 | 505 | 1997 |
How curved membranes recruit amphipathic helices and protein anchoring motifs NS Hatzakis, VK Bhatia, J Larsen, KL Madsen, PY Bolinger, AH Kunding, ... Nature chemical biology 5 (11), 835-841, 2009 | 471 | 2009 |
[Leu31, Pro34] neuropeptide Y: a specific Y1 receptor agonist. J Fuhlendorff, U Gether, L Aakerlund, N Langeland-Johansen, ... Proceedings of the National Academy of Sciences 87 (1), 182-186, 1990 | 470 | 1990 |
The binding sites for cocaine and dopamine in the dopamine transporter overlap T Beuming, J Kniazeff, ML Bergmann, L Shi, L Gracia, K Raniszewska, ... Nature neuroscience 11 (7), 780-789, 2008 | 418 | 2008 |
Neurotransmitter transporters: molecular function of important drug targets U Gether, PH Andersen, OM Larsson, A Schousboe Trends in pharmacological sciences 27 (7), 375-383, 2006 | 383 | 2006 |
Fluorescent labeling of purified β2 adrenergic receptor: evidence for ligand-specific conformational changes U Gether, S Lin, BK Kobilka Journal of Biological Chemistry 270 (47), 28268-28275, 1995 | 365 | 1995 |
Structural instability of a constitutively active G protein-coupled receptor: agonist-independent activation due to conformational flexibility U Gether, R Seifert, JA Ballesteros, E Sanders-Bush, H Weinstein, ... Journal of Biological Chemistry 272 (5), 2587-2590, 1997 | 353 | 1997 |
Amphipathic motifs in BAR domains are essential for membrane curvature sensing VK Bhatia, KL Madsen, PY Bolinger, A Kunding, P Hedegård, U Gether, ... The EMBO journal 28 (21), 3303-3314, 2009 | 300 | 2009 |
Mutation of a highly conserved aspartic acid in the β2 adrenergic receptor: constitutive activation, structural instability, and conformational rearrangement of transmembrane … SGF Rasmussen, AD Jensen, G Liapakis, P Ghanouni, JA Javitch, ... Molecular pharmacology 56 (1), 175-184, 1999 | 297 | 1999 |
Calmodulin kinase II interacts with the dopamine transporter C terminus to regulate amphetamine-induced reverse transport JU Fog, H Khoshbouei, M Holy, WA Owens, CB Vaegter, N Sen, ... Neuron 51 (4), 417-429, 2006 | 283 | 2006 |
Different binding epitopes on the NK1 receptor for substance P and a non-peptide antagonist U Gether, TE Johansen, RM Snider, JA Lowe III, S Nakanishi, ... Nature 362 (6418), 345-348, 1993 | 276 | 1993 |
Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype C Martinat, JJ Bacci, T Leete, J Kim, WB Vanti, AH Newman, JH Cha, ... Proceedings of the National Academy of Sciences 103 (8), 2874-2879, 2006 | 268 | 2006 |
The solute carrier 6 family of transporters S Bröer, U Gether British journal of pharmacology 167 (2), 256-278, 2012 | 258 | 2012 |
De novo mutation in the dopamine transporter gene associates dopamine dysfunction with autism spectrum disorder PJ Hamilton, NG Campbell, S Sharma, K Erreger, F Herborg Hansen, ... Molecular psychiatry 18 (12), 1315-1323, 2013 | 239 | 2013 |