Genome-wide association study identifies five loci associated with lung function E Repapi, I Sayers, LV Wain, PR Burton, T Johnson, M Obeidat, JH Zhao, ... Nature genetics 42 (1), 36-44, 2010 | 675 | 2010 |
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function MS Artigas, DW Loth, LV Wain, SA Gharib, M Obeidat, W Tang, G Zhai, ... Nature genetics 43 (11), 1082-1090, 2011 | 478 | 2011 |
IL-33 is more potent than IL-25 in provoking IL-13–producing nuocytes (type 2 innate lymphoid cells) and airway contraction JL Barlow, S Peel, J Fox, V Panova, CS Hardman, A Camelo, C Bucks, ... Journal of allergy and clinical immunology 132 (4), 933-941, 2013 | 453 | 2013 |
Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank LV Wain, N Shrine, S Miller, VE Jackson, I Ntalla, MS Artigas, ... The Lancet Respiratory Medicine 3 (10), 769-781, 2015 | 448 | 2015 |
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries N Shrine, AL Guyatt, AM Erzurumluoglu, VE Jackson, BD Hobbs, ... Nature genetics 51 (3), 481-493, 2019 | 389 | 2019 |
Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets LV Wain, N Shrine, MS Artigas, AM Erzurumluoglu, B Noyvert, ... Nature genetics 49 (3), 416-425, 2017 | 297 | 2017 |
Variant LTC4 synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast AP Sampson, S Siddiqui, D Buchanan, PH Howarth, ST Holgate, ... Thorax 55 (suppl 2), S28-S31, 2000 | 289 | 2000 |
Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study RJ Allen, J Porte, R Braybrooke, C Flores, TE Fingerlin, JM Oldham, ... The Lancet respiratory medicine 5 (11), 869-880, 2017 | 270 | 2017 |
Genome-wide association study of susceptibility to idiopathic pulmonary fibrosis RJ Allen, B Guillen-Guio, JM Oldham, SF Ma, A Dressen, ML Paynton, ... American journal of respiratory and critical care medicine 201 (5), 564-574, 2020 | 257 | 2020 |
Genetic risk factors for the development of allergic disease identified by genome‐wide association MA Portelli, E Hodge, I Sayers Clinical & Experimental Allergy 45 (1), 21-31, 2015 | 256 | 2015 |
Evaluation of differentiated human bronchial epithelial cell culture systems for asthma research CE Stewart, EE Torr, NH Mohd Jamili, C Bosquillon, I Sayers Journal of allergy 2012 (1), 943982, 2012 | 255 | 2012 |
Genome-wide association study to identify genetic determinants of severe asthma YI Wan, NRG Shrine, MS Artigas, LV Wain, JD Blakey, MF Moffatt, A Bush, ... Thorax 67 (9), 762-768, 2012 | 235 | 2012 |
Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study N Shrine, MA Portelli, C John, MS Artigas, N Bennett, R Hall, J Lewis, ... The Lancet Respiratory Medicine 7 (1), 20-34, 2019 | 219 | 2019 |
Polymorphisms in the interleukin‐4 and interleukin‐4 receptor α chain genes confer susceptibility to asthma and atopy in a Caucasian population B Beghé, S Barton, S Rorke, Q Peng, I Sayers, T Gaunt, TP Keith, ... Clinical & Experimental Allergy 33 (8), 1111-1117, 2003 | 219 | 2003 |
Epithelial cell dysfunction, a major driver of asthma development IH Heijink, VNS Kuchibhotla, MP Roffel, T Maes, DA Knight, I Sayers, ... Allergy 75 (8), 1902-1917, 2020 | 212 | 2020 |
Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function M Soler Artigas, LV Wain, E Repapi, M Obeidat, I Sayers, PR Burton, ... American journal of respiratory and critical care medicine 184 (7), 786-795, 2011 | 168 | 2011 |
Genome-wide association analysis identifies six new loci associated with forced vital capacity DW Loth, MS Artigas, SA Gharib, LV Wain, N Franceschini, B Koch, ... Nature genetics 46 (7), 669-677, 2014 | 164 | 2014 |
Leukotriene pathway genetics and pharmacogenetics in allergy NP Duroudier, AS Tulah, I Sayers Allergy 64 (6), 823-839, 2009 | 144 | 2009 |
Meta-analysis of genome-wide linkage studies of asthma and related traits S Denham, GH Koppelman, J Blakey, M Wjst, MA Ferreira, IP Hall, ... Respiratory research 9, 1-12, 2008 | 139 | 2008 |
β2-adrenoceptor polymorphisms and asthma from childhood to middle age in the British 1958 birth cohort: a genetic association study IP Hall, JD Blakey, KA Al Balushi, A Wheatley, I Sayers, ME Pembrey, ... The Lancet 368 (9537), 771-779, 2006 | 121 | 2006 |