The Rac-FRET mouse reveals tight spatiotemporal control of Rac activity in primary cells and tissues AKE Johnsson, Y Dai, M Nobis, MJ Baker, EJ McGhee, S Walker, ... Cell reports 6 (6), 1153-1164, 2014 | 97 | 2014 |
The role of Rac in tumor susceptibility and disease progression: from biochemistry to the clinic V Casado-Medrano, MJ Baker, C Lopez-Haber, M Cooke, S Wang, ... Biochemical Society Transactions 46 (4), 1003-1012, 2018 | 30 | 2018 |
Small GTPases and their guanine-nucleotide exchange factors and GTPase-activating proteins in neutrophil recruitment MJ Baker, D Pan, HCE Welch Current opinion in hematology 23 (1), 44-54, 2016 | 30 | 2016 |
Norbin stimulates the catalytic activity and plasma membrane localization of the guanine-nucleotide exchange factor P-Rex1 D Pan, MA Barber, K Hornigold, MJ Baker, JM Toth, D Oxley, HCE Welch Journal of Biological Chemistry, jbc. M115. 686592, 2016 | 28 | 2016 |
FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma M Cooke, G Kreider-Letterman, MJ Baker, S Zhang, NT Sullivan, ... Cell Reports 37 (5), 109905, 2021 | 26 | 2021 |
Rac-GEF/Rac signaling and metastatic dissemination in lung cancer M Cooke, MJ Baker, MG Kazanietz Frontiers in Cell and Developmental Biology 8, 118, 2020 | 25 | 2020 |
Characterization of AJH-836, a DAG-lactone with selectivity for novel PKC isozymes M Cooke, X Zhou, V Casado-Medrano, C Lopez-Haber, MJ Baker, R Garg, ... Journal of Biological Chemistry, jbc. RA117. 000235, 2018 | 23 | 2018 |
Nuclear PKCι-ECT2-Rac1 and ribosome biogenesis: a novel axis in lung tumorigenesis MJ Baker, M Cooke, MG Kazanietz Cancer cell 31 (2), 167-169, 2017 | 21 | 2017 |
Activating RAC1 variants in the switch II region cause a developmental syndrome and alter neuronal morphology S Banka, A Bennington, MJ Baker, E Rijckmans, G Clemente, NM Ansor, ... Brain, 2022 | 19 | 2022 |
The PKC universe keeps expanding: From cancer initiation to metastasis N Rahimova, M Cooke, S Zhang, MJ Baker, MG Kazanietz Advances in Biological Regulation 78, 100755, 2020 | 19 | 2020 |
PKCε regulates Rho GTPases and actin cytoskeleton reorganization in non-small cell lung cancer cells M Cooke, MJ Baker, MG Kazanietz, V Casado-Medrano Small GTPases 12 (3), 202-208, 2019 | 15 | 2019 |
Mechanical strain stimulates COPII‐dependent secretory trafficking via Rac1 S Phuyal, E Djaerff, AL Le Roux, MJ Baker, D Fankhauser, ... The EMBO Journal 41 (18), e110596, 2022 | 14 | 2022 |
The P-Rex1/Rac signaling pathway as a point of convergence for HER/ErbB receptor and GPCR responses MG Kazanietz, L Barrio-Real, V Casado-Medrano, MJ Baker, ... Small GTPases, 1-7, 2016 | 14 | 2016 |
P-REX1-Independent, Calcium-Dependent RAC1 Hyperactivation in Prostate Cancer MJ Baker, MC Abba, R Garcia-Mata, MG Kazanietz Cancers 12 (2), 480, 2020 | 13 | 2020 |
The GPCR adaptor protein norbin suppresses the neutrophil-mediated immunity of mice to pneumococcal infection C Pantarelli, D Pan, S Chetwynd, AK Stark, K Hornigold, P Machin, ... Blood Advances 5 (16), 3076-3091, 2021 | 10 | 2021 |
Evaluation of active Rac1 levels in cancer cells: A case of misleading conclusions from immunofluorescence analysis MJ Baker, M Cooke, G Kreider-Letterman, R Garcia-Mata, PA Janmey, ... Journal of Biological Chemistry 295 (40), 13698-13710, 2020 | 10 | 2020 |
A TIAM1-TRIM28 complex mediates epigenetic silencing of protocadherins to promote migration of lung cancer cells L Ginn, J Maltas, MJ Baker, A Chaturvedi, L Wilson, R Guilbert, ... Proceedings of the National Academy of Sciences 120 (40), e2300489120, 2023 | 6 | 2023 |
Germline intergenic duplications at Xq26.1 underlie Bazex‐Dupré‐Christol basal cell carcinoma susceptibility syndrome Y Liu, S Banka, Y Huang, J Hardman-Smart, D Pye, A Torrelo, ... British Journal of Dermatology 187 (6), 948-961, 2022 | 6 | 2022 |
Active GTPase Pulldown Protocol MJ Baker, I Rubio Ras Activity and Signaling, 117-135, 2021 | 6 | 2021 |
P-Rex1 Controls Sphingosine 1-Phosphate Receptor Signalling, Morphology, and Cell-Cycle Progression in Neuronal Cells E Hampson, E Tsonou, MJ Baker, DC Hornigold, RE Hubbard, A Massey, ... Cells 10 (9), 2474, 2021 | 2 | 2021 |