A large-scale, consortium-based genomewide association study of asthma GC Moffatt MF, Gut IG, Demenais F, Strachan DP New England Journal of Medicine 363 (13), 1211-1221, 2010 | 2400 | 2010 |
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes AP Morris, BF Voight, TM Teslovich, T Ferreira, AV Segré, ... Nature genetics 44 (9), 981, 2012 | 2156 | 2012 |
The genetic architecture of type 2 diabetes C Fuchsberger, J Flannick, TM Teslovich, A Mahajan, V Agarwala, ... Nature 536 (7614), 41-47, 2016 | 1249 | 2016 |
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium Nature genetics 46 (3), 234-244, 2014 | 908 | 2014 |
DNA methylation in newborns and maternal smoking in pregnancy: genome-wide consortium meta-analysis BR Joubert, JF Felix, P Yousefi, KM Bakulski, AC Just, C Breton, ... The American Journal of Human Genetics 98 (4), 680-696, 2016 | 888 | 2016 |
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. G EArly, EEEC Lifecourse, AGCA Australian, AAG Consortium Nature genetics 47 (12), 1449, 2015 | 598 | 2015 |
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks F Demenais, P Margaritte-Jeannin, KC Barnes, WOC Cookson, ... Nature genetics 50 (1), 42-53, 2018 | 486 | 2018 |
HLA has strongest association with IgA nephropathy in genome-wide analysis J Feehally, M Farrall, A Boland, DP Gale, I Gut, S Heath, A Kumar, ... Journal of the American Society of Nephrology: JASN 21 (10), 1791, 2010 | 309 | 2010 |
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls J Flannick, JM Mercader, C Fuchsberger, MS Udler, A Mahajan, J Wessel, ... Nature 570 (7759), 71-76, 2019 | 286 | 2019 |
A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order A Ramasamy, I Curjuric, LJ Coin, A Kumar, WL McArdle, M Imboden, ... Journal of Allergy and Clinical Immunology 128 (5), 996-1005, 2011 | 273 | 2011 |
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation JL Min, G Hemani, E Hannon, KF Dekkers, J Castillo-Fernandez, R Luijk, ... Nature genetics 53 (9), 1311-1321, 2021 | 240 | 2021 |
DNA methylation in childhood asthma: an epigenome-wide meta-analysis CJ Xu, C Söderhäll, M Bustamante, N Baïz, O Gruzieva, U Gehring, ... The lancet Respiratory medicine 6 (5), 379-388, 2018 | 212 | 2018 |
Epigenome-Wide Meta-Analysis of Methylation in Children Related to Prenatal NO2 Air Pollution Exposure O Gruzieva, CJ Xu, CV Breton, I Annesi-Maesano, JM Antó, C Auffray, ... Environmental health perspectives 125 (1), 104-110, 2017 | 206 | 2017 |
Evaluating empirical bounds on complex disease genetic architecture V Agarwala, J Flannick, S Sunyaev, D Altshuler, GoT2D Consortium Nature genetics 45 (12), 1418, 2013 | 190 | 2013 |
A Central Role for GRB10 in Regulation of Islet Function in Man I Prokopenko, W Poon, R Mägi, R Prasad, SA Salehi, P Almgren, ... PLoS genetics 10 (4), e1004235, 2014 | 185 | 2014 |
Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes AR Majithia, J Flannick, P Shahinian, M Guo, MA Bray, P Fontanillas, ... Proceedings of the National Academy of Sciences 111 (36), 13127-13132, 2014 | 177 | 2014 |
The power of gene-based rare variant methods to detect disease-associated variation and test hypotheses about complex disease L Moutsianas, V Agarwala, C Fuchsberger, J Flannick, MA Rivas, ... PLoS genetics 11 (4), e1005165, 2015 | 171 | 2015 |
Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation MS Artigas, LV Wain, S Miller, AK Kheirallah, JE Huffman, I Ntalla, ... Nature communications 6 (1), 1-12, 2015 | 140 | 2015 |
1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function M Gorski, PJ Van Der Most, A Teumer, AY Chu, M Li, V Mijatovic, IM Nolte, ... Scientific reports 7 (1), 1-11, 2017 | 134 | 2017 |
Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis J Waage, M Standl, JA Curtin, LE Jessen, J Thorsen, C Tian, N Schoettler, ... Nature genetics 50 (8), 1072-1080, 2018 | 129 | 2018 |