Excessive activation of mTOR in postnatally generated granule cells is sufficient to cause epilepsy RYK Pun, IJ Rolle, CL LaSarge, BE Hosford, JM Rosen, JD Uhl, ... Neuron 75 (6), 1022-1034, 2012 | 268 | 2012 |
Mechanisms regulating neuronal excitability and seizure development following mTOR pathway hyperactivation CL LaSarge, SC Danzer Frontiers in molecular neuroscience 7, 18, 2014 | 204 | 2014 |
Spatial reference and working memory across the lifespan of male Fischer 344 rats JL Bizon, CL LaSarge, KS Montgomery, AN McDermott, B Setlow, ... Neurobiology of aging 30 (4), 646-655, 2009 | 188 | 2009 |
Dopaminergic modulation of risky decision-making NW Simon, KS Montgomery, BS Beas, MR Mitchell, CL LaSarge, ... Journal of Neuroscience 31 (48), 17460-17470, 2011 | 167 | 2011 |
Good things come to those who wait: attenuated discounting of delayed rewards in aged Fischer 344 rats NW Simon, CL LaSarge, KS Montgomery, MT Williams, IA Mendez, ... Neurobiology of aging 31 (5), 853-862, 2010 | 105 | 2010 |
Deficits across multiple cognitive domains in a subset of aged Fischer 344 rats CL LaSarge, KS Montgomery, C Tucker, GS Slaton, WH Griffith, B Setlow, ... Neurobiology of aging 28 (6), 928-936, 2007 | 82 | 2007 |
Long-term effects of prior cocaine exposure on Morris water maze performance IA Mendez, KS Montgomery, CL LaSarge, NW Simon, JL Bizon, B Setlow Neurobiology of learning and memory 89 (2), 185-191, 2008 | 73 | 2008 |
Blockade of GABA (B) receptors completely reverses age-related learning impairment CL LaSarge, C Bañuelos, JD Mayse, JL Bizon Neuroscience 164 (3), 941-947, 2009 | 57 | 2009 |
Impact of rapamycin on status epilepticus induced hippocampal pathology and weight gain MS Hester, BE Hosford, VR Santos, SP Singh, IJ Rolle, CL LaSarge, ... Experimental neurology 280, 1-12, 2016 | 51 | 2016 |
Age-related changes in rostral basal forebrain cholinergic and GABAergic projection neurons: relationship with spatial impairment C Bañuelos, CL LaSarge, JA McQuail, JJ Hartman, RJ Gilbert, ... Neurobiology of aging 34 (3), 845-862, 2013 | 47 | 2013 |
PTEN deletion increases hippocampal granule cell excitability in male and female mice VR Santos, RYK Pun, SR Arafa, CL LaSarge, S Rowley, S Khademi, ... Neurobiology of disease 108, 339-351, 2017 | 42 | 2017 |
GABAB receptor GTP-binding is decreased in the prefrontal cortex but not the hippocampus of aged rats JA McQuail, C Bañuelos, CL LaSarge, MM Nicolle, JL Bizon Neurobiology of aging 33 (6), 1124. e1-1124. e12, 2012 | 41 | 2012 |
Enhanced calcium buffering in F344 rat cholinergic basal forebrain neurons is associated with age-related cognitive impairment D Murchison, AN McDermott, CL LaSarge, KA Peebles, JL Bizon, ... Journal of neurophysiology 102 (4), 2194-2207, 2009 | 40 | 2009 |
Clonal analysis of newborn hippocampal dentate granule cell proliferation and development in temporal lobe epilepsy SP Singh, CL LaSarge, A An, JJ McAuliffe, SC Danzer Eneuro 2 (6), 2015 | 39 | 2015 |
PTEN deletion from adult-generated dentate granule cells disrupts granule cell mossy fiber axon structure CL LaSarge, VR Santos, SC Danzer Neurobiology of disease 75, 142-150, 2015 | 34 | 2015 |
Disrupted hippocampal network physiology following PTEN deletion from newborn dentate granule cells CL LaSarge, RYK Pun, MB Muntifering, SC Danzer Neurobiology of disease 96, 105-114, 2016 | 27 | 2016 |
Comparison of different cognitive rat models of human aging C LaSarge, M Nicolle Animal models of human cognitive aging, 1-30, 2009 | 22 | 2009 |
mTOR-driven neural circuit changes initiate an epileptogenic cascade CL LaSarge, RYK Pun, Z Gu, MR Riccetti, DV Namboodiri, D Tiwari, ... Progress in neurobiology 200, 101974, 2021 | 15 | 2021 |
Self-reinforcing effects of mTOR hyperactive neurons on dendritic growth SR Arafa, CL LaSarge, RYK Pun, S Khademi, SC Danzer Experimental Neurology 311, 125-134, 2019 | 14 | 2019 |
Animal models of human cognitive aging CL LaSarge, MM Nicolle | 11 | 2009 |