Platelet factor 4 binds to bacteria, inducing antibodies cross-reacting with the major antigen in heparin-induced thrombocytopenia K Krauel, C Pötschke, C Weber, W Kessler, B Fürll, T Ittermann, S Maier, ... Blood, The Journal of the American Society of Hematology 117 (4), 1370-1378, 2011 | 285 | 2011 |
Amplification of bacteria-induced platelet activation is triggered by FcγRIIA, integrin αIIbβ3, and platelet factor 4 M Arman, K Krauel, DO Tilley, C Weber, D Cox, A Greinacher, ... Blood, The Journal of the American Society of Hematology 123 (20), 3166-3174, 2014 | 176 | 2014 |
Complex formation with nucleic acids and aptamers alters the antigenic properties of platelet factor 4 ME Jaax, K Krauel, T Marschall, S Brandt, J Gansler, B Fürll, B Appel, ... Blood, The Journal of the American Society of Hematology 122 (2), 272-281, 2013 | 173 | 2013 |
Human platelet IgG Fc receptor FcγRIIA in immunity and thrombosis M Arman, K Krauel Journal of Thrombosis and Haemostasis 13 (6), 893-908, 2015 | 164 | 2015 |
Heparin-induced thrombocytopenia: in vitro studies on the interaction of dabigatran, rivaroxaban, and low-sulfated heparin, with platelet factor 4 and anti-PF4/heparin antibodies K Krauel, C Hackbarth, B Fürll, A Greinacher Blood, The Journal of the American Society of Hematology 119 (5), 1248-1255, 2012 | 161 | 2012 |
Sepsis alters the transcriptional and translational landscape of human and murine platelets EA Middleton, JW Rowley, RA Campbell, CK Grissom, SM Brown, ... Blood, The Journal of the American Society of Hematology 134 (12), 911-923, 2019 | 131 | 2019 |
Platelet factor 4 binding to lipid A of Gram-negative bacteria exposes PF4/heparin-like epitopes K Krauel, C Weber, S Brandt, U Zähringer, U Mamat, A Greinacher, ... Blood, The Journal of the American Society of Hematology 120 (16), 3345-3352, 2012 | 129 | 2012 |
Association of natural anti-platelet factor 4/heparin antibodies with periodontal disease A Greinacher, B Holtfreter, K Krauel, D Gätke, C Weber, T Ittermann, ... Blood, The Journal of the American Society of Hematology 118 (5), 1395-1401, 2011 | 121 | 2011 |
Binding of anti–platelet factor 4/heparin antibodies depends on the thermodynamics of conformational changes in platelet factor 4 M Kreimann, S Brandt, K Krauel, S Block, CA Helm, W Weitschies, ... Blood, The Journal of the American Society of Hematology 124 (15), 2442-2449, 2014 | 96 | 2014 |
Platelets kill bacteria by bridging innate and adaptive immunity via platelet factor 4 and FcγRIIA R Palankar, TP Kohler, K Krauel, J Wesche, S Hammerschmidt, ... Journal of Thrombosis and Haemostasis 16 (6), 1187-1197, 2018 | 93 | 2018 |
Heparin‐induced thrombocytopenia–therapeutic concentrations of danaparoid, unlike fondaparinux and direct thrombin inhibitors, inhibit formation of platelet factor 4–heparin … K Krauel, B Fürll, TE Warkentin, W Weitschies, T Kohlmann, JI Sheppard, ... Journal of Thrombosis and Haemostasis 6 (12), 2160-2167, 2008 | 85 | 2008 |
Characterisation of the conformational changes in platelet factor 4 induced by polyanions: towards in vitro prediction of antigenicity S Brandt, K Krauel, KE Gottschalk, T Renné, CA Helm, A Greinacher, ... Thrombosis and haemostasis 112 (07), 53-64, 2014 | 84 | 2014 |
Heparin-induced thrombocytopenia A Greinacher, K Althaus, K Krauel, S Selleng Hämostaseologie 30 (01), 17-28, 2010 | 76 | 2010 |
Platelet MHC class I mediates CD8+ T-cell suppression during sepsis L Guo, S Shen, JW Rowley, ND Tolley, W Jia, BK Manne, KN McComas, ... Blood, The Journal of the American Society of Hematology 138 (5), 401-416, 2021 | 64 | 2021 |
Polyphosphates form antigenic complexes with platelet factor 4 (PF4) and enhance PF4-binding to bacteria S Brandt, K Krauel, M Jaax, T Renné, CA Helm, S Hammerschmidt, ... Thrombosis and haemostasis 114 (12), 1189-1198, 2015 | 48 | 2015 |
Further insights into the anti-PF4/heparin IgM immune response K Krauel, A Schulze, R Jouni, C Hackbarth, B Hietkamp, S Selleng, ... Thrombosis and Haemostasis 115 (04), 752-761, 2016 | 43 | 2016 |
Pneumococcal adhesins PavB and PspC are important for the interplay with human thrombospondin-1 U Binsker, TP Kohler, K Krauel, S Kohler, H Schwertz, S Hammerschmidt Journal of Biological Chemistry 290 (23), 14542-14555, 2015 | 39 | 2015 |
Heparanase expression and activity are increased in platelets during clinical sepsis AS Eustes, RA Campbell, EA Middleton, ND Tolley, BK Manne, ... Journal of Thrombosis and Haemostasis 19 (5), 1319-1330, 2021 | 22 | 2021 |
Platelet olfactory receptor activation limits platelet reactivity and growth of aortic aneurysms CN Morrell, D Mix, A Aggarwal, R Bhandari, M Godwin, P Owens, ... The Journal of clinical investigation 132 (9), 2022 | 21 | 2022 |
Fibronectin modulates formation of PF4/heparin complexes and is a potential factor for reducing risk of developing HIT K Krauel, P Preuße, TE Warkentin, C Trabhardt, S Brandt, I Jensch, ... Blood, The Journal of the American Society of Hematology 133 (9), 978-989, 2019 | 17 | 2019 |