Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA MC Liu, GR Oxnard, EA Klein, C Swanton, MV Seiden, MC Liu, ... Annals of Oncology 31 (6), 745-759, 2020 | 1068 | 2020 |
Genome-wide linkage analysis of a Parkinsonian-pyramidal syndrome pedigree by 500 K SNP arrays S Shojaee, F Sina, SS Banihosseini, MH Kazemi, R Kalhor, GA Shahidi, ... The American Journal of Human Genetics 82 (6), 1375-1384, 2008 | 325 | 2008 |
Metabolic gatekeeper function of B-lymphoid transcription factors LN Chan, Z Chen, D Braas, JW Lee, G Xiao, H Geng, KN Cosgun, C Hurtz, ... Nature 542 (7642), 479-483, 2017 | 220 | 2017 |
BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR–ABL1 kinase inhibition C Duy, C Hurtz, S Shojaee, L Cerchietti, H Geng, S Swaminathan, ... Nature 473 (7347), 384-388, 2011 | 217 | 2011 |
Loss of function mutations in the gene encoding latent transforming growth factor beta binding protein 2, LTBP2, cause primary congenital glaucoma M Narooie-Nejad, SH Paylakhi, S Shojaee, Z Fazlali, M Rezaei Kanavi, ... Human molecular genetics 18 (20), 3969-3977, 2009 | 184 | 2009 |
Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia Z Chen, S Shojaee, M Buchner, H Geng, JW Lee, L Klemm, B Titz, ... Nature 521 (7552), 357-361, 2015 | 155 | 2015 |
BCL6 is critical for the development of a diverse primary B cell repertoire C Duy, JJ Yu, R Nahar, S Swaminathan, SM Kweon, JM Polo, E Valls, ... Journal of Experimental Medicine 207 (6), 1209-1221, 2010 | 143 | 2010 |
Integrin alpha4 blockade sensitizes drug resistant pre-B acute lymphoblastic leukemia to chemotherapy YT Hsieh, EJ Gang, H Geng, E Park, S Huantes, D Chudziak, K Dauber, ... Blood, The Journal of the American Society of Hematology 121 (10), 1814-1818, 2013 | 139 | 2013 |
Erk negative feedback control enables pre-B cell transformation and represents a therapeutic target in acute lymphoblastic leukemia S Shojaee, R Caeser, M Buchner, E Park, S Swaminathan, C Hurtz, ... Cancer cell 28 (1), 114-128, 2015 | 132 | 2015 |
Evaluation of cell-free DNA approaches for multi-cancer early detection A Jamshidi, MC Liu, EA Klein, O Venn, E Hubbell, JF Beausang, S Gross, ... Cancer Cell 40 (12), 1537-1549. e12, 2022 | 131 | 2022 |
Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia H Geng, C Hurtz, KB Lenz, Z Chen, D Baumjohann, S Thompson, ... Cancer cell 27 (3), 409-425, 2015 | 131 | 2015 |
PTEN opposes negative selection and enables oncogenic transformation of pre-B cells S Shojaee, LN Chan, M Buchner, V Cazzaniga, KN Cosgun, H Geng, ... Nature medicine 22 (4), 379-387, 2016 | 128 | 2016 |
R632W mutation in PLA2G6 segregates with dystonia‐parkinsonism in a consanguineous Iranian family F Sina, S Shojaee, E Elahi, C Paisan‐Ruiz European journal of neurology 16 (1), 101-104, 2009 | 109 | 2009 |
Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia H Geng, S Brennan, TA Milne, WY Chen, Y Li, C Hurtz, SM Kweon, L Zickl, ... Cancer discovery 2 (11), 1004-1023, 2012 | 89 | 2012 |
BCOR regulates myeloid cell proliferation and differentiation Q Cao, MD Gearhart, S Gery, S Shojaee, H Yang, H Sun, DC Lin, JW Bai, ... Leukemia 30 (5), 1155-1165, 2016 | 88 | 2016 |
Signalling input from divergent pathways subverts B cell transformation LN Chan, MA Murakami, ME Robinson, R Caeser, T Sadras, J Lee, ... Nature 583 (7818), 845-851, 2020 | 50 | 2020 |
Identification of p. Gln858* in ATP13A2 in two EOPD patients and presentation of their clinical features M Malakouti-Nejad, GA Shahidi, M Rohani, SM Shojaee, M Hashemi, ... Neuroscience letters 577, 106-111, 2014 | 33 | 2014 |
A clinic‐based screening of mutations in exons 31, 34, 35, 41, and 48 of LRRK2 in Iranian Parkinson's disease patients S Shojaee, F Sina, N Farboodi, Z Fazlali, F Ghazavi, SA Ghorashi, ... Movement Disorders 24 (7), 1023-1027, 2009 | 31 | 2009 |
PRKN, DJ‐1, and PINK1 screening identifies novel splice site mutation in PRKN and two novel DJ‐1 mutations F Ghazavi, Z Fazlali, SS Banihosseini, SR Hosseini, MH Kazemi, ... Movement disorders 26 (1), 80-89, 2011 | 25 | 2011 |
Analytical validation of a multi-cancer early detection test with cancer signal origin using a cell-free DNA–based targeted methylation assay GE Alexander, W Lin, FE Ortega, M Ramaiah, B Jung, L Ji, E Revenkova, ... PLoS One 18 (4), e0283001, 2023 | 13 | 2023 |