| Role for NLRP3 inflammasome–mediated, IL-1β–dependent responses in severe, steroid-resistant asthma RY Kim, JW Pinkerton, AT Essilfie, AAB Robertson, KJ Baines, AC Brown, ... American journal of respiratory and critical care medicine 196 (3), 283-297, 2017 | 380 | 2017 |
| A GABAergic system in airway epithelium is essential for mucus overproduction in asthma YY Xiang, S Wang, M Liu, JA Hirota, J Li, W Ju, Y Fan, MM Kelly, B Ye, ... Nature medicine 13 (7), 862-867, 2007 | 246 | 2007 |
| Group 2 innate lymphoid cells facilitate sensitization to local, but not systemic, TH2-inducing allergen exposures MJ Gold, F Antignano, TYF Halim, JA Hirota, MR Blanchet, C Zaph, ... Journal of Allergy and Clinical Immunology 133 (4), 1142-1148. e5, 2014 | 243 | 2014 |
| Type 2 cytokines in the pathogenesis of sustained airway dysfunction and airway remodeling in mice R Leigh, R Ellis, JN Wattie, JA Hirota, KI Matthaei, PS Foster, PM O'Byrne, ... American journal of respiratory and critical care medicine 169 (7), 860-867, 2004 | 224 | 2004 |
| The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter JA Hirota, SA Hirota, SM Warner, D Stefanowicz, F Shaheen, PL Beck, ... Journal of Allergy and Clinical Immunology 129 (4), 1116-1125. e6, 2012 | 213 | 2012 |
| Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue JA Aguiar, BJM Tremblay, MJ Mansfield, O Woody, B Lobb, A Banerjee, ... European Respiratory Journal 56 (3), 2020 | 181 | 2020 |
| Inflammasomes in the lung JW Pinkerton, RY Kim, AAB Robertson, JA Hirota, LG Wood, DA Knight, ... Molecular immunology 86, 44-55, 2017 | 178 | 2017 |
| Animal models of COPD: W hat do they tell us? B Jones, C Donovan, G Liu, HM Gomez, V Chimankar, CL Harrison, ... Respirology 22 (1), 21-32, 2017 | 157 | 2017 |
| Mechanisms and treatments for severe, steroid‐resistant allergic airway disease and asthma PM Hansbro, RY Kim, MR Starkey, C Donovan, K Dua, JR Mayall, G Liu, ... Immunological reviews 278 (1), 41-62, 2017 | 135 | 2017 |
| Isolation, sequence, infectivity, and replication kinetics of severe acute respiratory syndrome coronavirus 2 A Banerjee, JA Nasir, P Budylowski, L Yip, P Aftanas, N Christie, ... Emerging infectious diseases 26 (9), 2054, 2020 | 129 | 2020 |
| Diesel exhaust augments allergen-induced lower airway inflammation in allergic individuals: a controlled human exposure study C Carlsten, A Blomberg, M Pui, T Sandstrom, SW Wong, N Alexis, J Hirota Thorax 71 (1), 35-44, 2016 | 126 | 2016 |
| Increased eosinophil-lineage committed progenitors in the lung of allergen-challenged mice DS Southam, N Widmer, R Ellis, JA Hirota, MD Inman, R Sehmi Journal of allergy and clinical immunology 115 (1), 95-102, 2005 | 109 | 2005 |
| Airway smooth muscle in asthma: phenotype plasticity and function JA Hirota, TTB Nguyen, D Schaafsma, P Sharma, T Tran Pulmonary pharmacology & therapeutics 22 (5), 370-378, 2009 | 97 | 2009 |
| The nucleotide-binding domain, leucine-rich repeat protein 3 inflammasome/IL-1 receptor I axis mediates innate, but not adaptive, immune responses after exposure to particulate … JA Hirota, MJ Gold, PR Hiebert, LG Parkinson, T Wee, D Smith, ... American journal of respiratory cell and molecular biology 52 (1), 96-105, 2015 | 96 | 2015 |
| An update on immunologic mechanisms in the respiratory mucosa in response to air pollutants RD Huff, C Carlsten, JA Hirota Journal of allergy and clinical immunology 143 (6), 1989-2001, 2019 | 95 | 2019 |
| Controlled diesel exhaust and allergen coexposure modulates microRNA and gene expression in humans: effects on inflammatory lung markers CF Rider, M Yamamoto, OP Günther, JA Hirota, A Singh, SJ Tebbutt, ... Journal of Allergy and Clinical Immunology 138 (6), 1690-1700, 2016 | 83 | 2016 |
| Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome I Pablos, Y Machado, HCR de Jesus, Y Mohamud, R Kappelhoff, ... Cell reports 37 (4), 2021 | 78 | 2021 |
| Mucosal production of uric acid by airway epithelial cells contributes to particulate matter-induced allergic sensitization MJ Gold, PR Hiebert, HY Park, D Stefanowicz, A Le, MR Starkey, A Deane, ... Mucosal immunology 9 (3), 809-820, 2016 | 72 | 2016 |
| Gob-5 is not essential for mucus overproduction in preclinical murine models of allergic asthma A Robichaud, SA Tuck, S Kargman, J Tam, E Wong, M Abramovitz, ... American journal of respiratory cell and molecular biology 33 (3), 303-314, 2005 | 72 | 2005 |
| Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia S Ahmadi, Z Bozoky, M Di Paola, S Xia, C Li, AP Wong, L Wellhauser, ... NPJ genomic medicine 2 (1), 12, 2017 | 71 | 2017 |
Kjetil AskNovartis, Biomedical Research, DAx & Adjunct Associate Professor, McMaster University在 mcmaster.ca 的电子邮件经过验证
