| Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1 X Wu, ZY Yang, Y Li, CM Hogerkorp, WR Schief, MS Seaman, T Zhou, ... Science 329 (5993), 856-861, 2010 | 2033 | 2010 |
| Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike L Liu, P Wang, MS Nair, J Yu, M Rapp, Q Wang, Y Luo, JFW Chan, V Sahi, ... Nature 584 (7821), 450-456, 2020 | 1413 | 2020 |
| Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01 T Zhou, I Georgiev, X Wu, ZY Yang, K Dai, A Finzi, Y Do Kwon, JF Scheid, ... Science 329 (5993), 811-817, 2010 | 1343 | 2010 |
| Evaluation of the mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates KS Corbett, B Flynn, KE Foulds, JR Francica, S Boyoglu-Barnum, ... New England Journal of Medicine 383 (16), 1544-1555, 2020 | 1164 | 2020 |
| Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus HX Liao, R Lynch, T Zhou, F Gao, SM Alam, SD Boyd, AZ Fire, KM Roskin, ... Nature 496 (7446), 469-476, 2013 | 1141 | 2013 |
| Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9 JS McLellan, M Pancera, C Carrico, J Gorman, JP Julien, R Khayat, ... Nature 480 (7377), 336-343, 2011 | 1038 | 2011 |
| Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus JS McLellan, M Chen, MG Joyce, M Sastry, GBE Stewart-Jones, Y Yang, ... science 342 (6158), 592-598, 2013 | 994 | 2013 |
| Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing X Wu, T Zhou, J Zhu, B Zhang, I Georgiev, C Wang, X Chen, NS Longo, ... Science 333 (6049), 1593-1602, 2011 | 969 | 2011 |
| Structural definition of a conserved neutralization epitope on HIV-1 gp120 T Zhou, L Xu, B Dey, AJ Hessell, D Van Ryk, SH Xiang, X Yang, ... Nature 445 (7129), 732-737, 2007 | 964 | 2007 |
| Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody JS McLellan, M Chen, S Leung, KW Graepel, X Du, Y Yang, T Zhou, ... Science 340 (6136), 1113-1117, 2013 | 843 | 2013 |
| Structure and immune recognition of trimeric pre-fusion HIV-1 Env M Pancera, T Zhou, A Druz, IS Georgiev, C Soto, J Gorman, J Huang, ... Nature 514 (7523), 455-461, 2014 | 832 | 2014 |
| Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization F Klein, R Diskin, JF Scheid, C Gaebler, H Mouquet, IS Georgiev, ... Cell 153 (1), 126-138, 2013 | 636 | 2013 |
| Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility M Pancera, S Majeed, YEA Ban, L Chen, C Huang, L Kong, YD Kwon, ... Proceedings of the National Academy of Sciences 107 (3), 1166-1171, 2010 | 478 | 2010 |
| Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite G Cerutti, Y Guo, T Zhou, J Gorman, M Lee, M Rapp, ER Reddem, J Yu, ... Cell host & microbe 29 (5), 819-833. e7, 2021 | 465 | 2021 |
| Trimeric HIV-1-Env structures define glycan shields from clades A, B, and G GBE Stewart-Jones, C Soto, T Lemmin, GY Chuang, A Druz, R Kong, ... Cell 165 (4), 813-826, 2016 | 419 | 2016 |
| Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120 L Chen, Y Do Kwon, T Zhou, X Wu, S O’Dell, L Cavacini, AJ Hessell, ... Science 326 (5956), 1123-1127, 2009 | 376 | 2009 |
| Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies T Zhou, J Zhu, X Wu, S Moquin, B Zhang, P Acharya, IS Georgiev, ... Immunity 39 (2), 245-258, 2013 | 374 | 2013 |
| Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env Y Do Kwon, M Pancera, P Acharya, IS Georgiev, ET Crooks, J Gorman, ... Nature structural & molecular biology 22 (7), 522-531, 2015 | 371 | 2015 |
| SARS-CoV-2 Omicron variant neutralization after mRNA-1273 booster vaccination R Pajon, NA Doria-Rose, X Shen, SD Schmidt, S O’Dell, C McDanal, ... New England Journal of Medicine 386 (11), 1088-1091, 2022 | 366 | 2022 |
| LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants K Westendorf, S Žentelis, L Wang, D Foster, P Vaillancourt, M Wiggin, ... Cell reports 39 (7), 2022 | 358 | 2022 |
Gwo-Yu ChuangVaccine Research Center, NIAID/NIH在 nih.gov 的电子邮件经过验证
