Hyocholic acid species improve glucose homeostasis through a distinct TGR5 and FXR signaling mechanism X Zheng, T Chen, R Jiang, A Zhao, Q Wu, J Kuang, D Sun, Z Ren, M Li, ... Cell metabolism 33 (4), 791-803. e7, 2021 | 252 | 2021 |
Antihyperlipidemic effect of protodioscin, an active ingredient isolated from the rhizomes of Dioscorea nipponica T Wang, RCY Choi, J Li, CWC Bi, L Zang, Z Liu, TTX Dong, K Bi, ... Planta medica 76 (15), 1642-1646, 2010 | 112* | 2010 |
An integrated metabolomics and pharmacokinetics strategy for multi-component drugs evaluation K Lan, W Jia Current drug metabolism 11 (1), 105-114, 2010 | 82 | 2010 |
Quantitative determination of rosuvastatin in human plasma by ion pair liquid–liquid extraction using liquid chromatography with electrospray ionization tandem mass spectrometry K Lan, X Jiang, Y Li, L Wang, J Zhou, Q Jiang, L Ye Journal of pharmaceutical and biomedical analysis 44 (2), 540-546, 2007 | 73 | 2007 |
Metabolic fate of tea polyphenols in humans G Xie, A Zhao, L Zhao, T Chen, H Chen, X Qi, X Zheng, Y Ni, Y Cheng, ... Journal of Proteome Research 11 (6), 3449-3457, 2012 | 61 | 2012 |
Key role for the 12-hydroxy group in the negative ion fragmentation of unconjugated C24 bile acids K Lan, M Su, G Xie, BC Ferslew, KLR Brouwer, C Rajani, C Liu, W Jia Analytical chemistry 88 (14), 7041-7048, 2016 | 60 | 2016 |
Towards polypharmacokinetics: pharmacokinetics of multicomponent drugs and herbal medicines using a metabolomics approach K Lan, G Xie, W Jia Evidence‐Based Complementary and Alternative Medicine 2013 (1), 819147, 2013 | 56 | 2013 |
Intra‐herb pharmacokinetics interaction between quercetin and isorhamentin1 K Lan, J HE, Y Tian, F Tan, X JIANG, L Wang, L YE Acta Pharmacologica Sinica 29 (11), 1376-1382, 2008 | 56 | 2008 |
Pharmacokinetic properties of rosuvastatin after single-dose, oral administration in Chinese volunteers: a randomized, open-label, three-way crossover study Y Li, X Jiang, K Lan, R Zhang, X Li, Q Jiang Clinical therapeutics 29 (10), 2194-2203, 2007 | 56 | 2007 |
Simple quality assessment approach for herbal extracts using high performance liquid chromatography-UV based metabolomics platform K Lan, Y Zhang, J Yang, L Xu Journal of Chromatography A 1217 (8), 1414-1418, 2010 | 55 | 2010 |
Factors affecting separation and detection of bile acids by liquid chromatography coupled with mass spectrometry in negative mode S Yin, M Su, G Xie, X Li, R Wei, C Liu, K Lan, W Jia Analytical and bioanalytical chemistry 409, 5533-5545, 2017 | 50 | 2017 |
An ultra-high sensitive bioanalytical method for plasma melatonin by liquid chromatography–tandem mass spectrometry using water as calibration matrix AQ Wang, BP Wei, Y Zhang, YJ Wang, L Xu, K Lan Journal of Chromatography B 879 (23), 2259-2264, 2011 | 40 | 2011 |
Quantitative determination of isorhamnetin, quercetin and kaempferol in rat plasma by liquid chromatography with electrospray ionization tandem mass spectrometry and its … K Lan, X Jiang, J He Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2007 | 38 | 2007 |
Poly‐pharmacokinetic study of a multicomponent herbal medicine in healthy Chinese volunteers G Xie, S Wang, H Zhang, A Zhao, J Liu, Y Ma, K Lan, Y Ni, C Liu, P Liu, ... Clinical Pharmacology & Therapeutics 103 (4), 692-702, 2018 | 36 | 2018 |
Analysis of human C24 bile acids metabolome in serum and urine based on enzyme digestion of conjugated bile acids and LC-MS determination of unconjugated bile acids P Zhu, J Zhang, Y Chen, S Yin, M Su, G Xie, KLR Brouwer, C Liu, K Lan, ... Analytical and bioanalytical chemistry 410, 5287-5300, 2018 | 34 | 2018 |
Study on the pharmacokinetics of scutellarin in dogs XH Jiang, SH Li, K Lan, JY Yang, J Zhou Yao xue xue bao= Acta Pharmaceutica Sinica 38 (5), 371-373, 2003 | 31 | 2003 |
Preparation, characterization and in vitro/vivo evaluation of tectorigenin solid dispersion with improved dissolution and bioavailability S Shuai, S Yue, Q Huang, W Wang, J Yang, K Lan, L Ye European journal of drug metabolism and pharmacokinetics 41, 413-422, 2016 | 30 | 2016 |
Species differences of bile acid redox metabolism: tertiary oxidation of deoxycholate is conserved in preclinical animals Q Lin, X Tan, W Wang, W Zeng, L Gui, M Su, C Liu, W Jia, L Xu, K Lan Drug Metabolism and Disposition 48 (6), 499-507, 2020 | 26 | 2020 |
A chemical profiling strategy for semi-quantitative analysis of flavonoids in Ginkgo extracts J Yang, AQ Wang, X Li, X Fan, SS Yin, K Lan Journal of Pharmaceutical and Biomedical Analysis 123, 147-154, 2016 | 26 | 2016 |
Continuum of host-gut microbial co-metabolism: host CYP3A4/3A7 are responsible for tertiary oxidations of deoxycholate species J Zhang, LZ Gao, YJ Chen, PP Zhu, SS Yin, MM Su, Y Ni, J Miao, WL Wu, ... Drug Metabolism and Disposition 47 (3), 283-294, 2019 | 24 | 2019 |