Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment H Yu, M Kortylewski, D Pardoll Nature reviews immunology 7 (1), 41-51, 2007 | 2156 | 2007 |
Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells T Wang, G Niu, M Kortylewski, L Burdelya, K Shain, S Zhang, ... Nature medicine 10 (1), 48-54, 2004 | 1451 | 2004 |
Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity M Kortylewski, M Kujawski, T Wang, S Wei, S Zhang, S Pilon-Thomas, ... Nature medicine 11 (12), 1314-1321, 2005 | 1267 | 2005 |
IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway L Wang, T Yi, M Kortylewski, DM Pardoll, D Zeng, H Yu Journal of experimental medicine 206 (7), 1457-1464, 2009 | 1015 | 2009 |
Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways Q Xu, J Briggs, S Park, G Niu, M Kortylewski, S Zhang, T Gritsko, ... Oncogene 24 (36), 5552-5560, 2005 | 764 | 2005 |
Cutting edge: An in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity TJ Harris, JF Grosso, HR Yen, H Xin, M Kortylewski, E Albesiano, ... The Journal of Immunology 179 (7), 4313-4317, 2007 | 732 | 2007 |
Stat3 mediates myeloid cell–dependent tumor angiogenesis in mice M Kujawski, M Kortylewski, H Lee, A Herrmann, H Kay, H Yu The Journal of clinical investigation 118 (10), 3367-3377, 2008 | 654 | 2008 |
Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment M Kortylewski, H Xin, M Kujawski, H Lee, Y Liu, T Harris, C Drake, ... Cancer cell 15 (2), 114-123, 2009 | 582 | 2009 |
STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors H Lee, J Deng, M Kujawski, C Yang, Y Liu, A Herrmann, M Kortylewski, ... Nature medicine 16 (12), 1421-1428, 2010 | 430 | 2010 |
In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses M Kortylewski, P Swiderski, A Herrmann, L Wang, C Kowolik, M Kujawski, ... Nature biotechnology 27 (10), 925-932, 2009 | 410 | 2009 |
Targeting STAT3 affects melanoma on multiple fronts M Kortylewski, R Jove, H Yu Cancer and Metastasis Reviews 24, 315-327, 2005 | 365 | 2005 |
Macrophage immunomodulation by breast cancer-derived exosomes requires Toll-like receptor 2-mediated activation of NF-κB A Chow, W Zhou, L Liu, MY Fong, J Champer, D Van Haute, AR Chin, ... Scientific reports 4 (1), 5750, 2014 | 345 | 2014 |
Nivolumab plus ipilimumab with or without live bacterial supplementation in metastatic renal cell carcinoma: a randomized phase 1 trial N Dizman, L Meza, P Bergerot, M Alcantara, T Dorff, Y Lyou, P Frankel, ... Nature medicine 28 (4), 704-712, 2022 | 248 | 2022 |
Role of Stat3 in suppressing anti-tumor immunity M Kortylewski, H Yu Current opinion in immunology 20 (2), 228-233, 2008 | 242 | 2008 |
Signal transducer and activator of transcription 3 is required for hypoxia-inducible factor-1α RNA expression in both tumor cells and tumor-associated myeloid cells G Niu, J Briggs, J Deng, Y Ma, H Lee, M Kortylewski, M Kujawski, H Kay, ... Molecular Cancer Research 6 (7), 1099-1105, 2008 | 236 | 2008 |
Stat3 inhibition activates tumor macrophages and abrogates glioma growth in mice L Zhang, D Alizadeh, M Van Handel, M Kortylewski, H Yu, B Badie Glia 57 (13), 1458-1467, 2009 | 205 | 2009 |
TLR9-targeted STAT3 silencing abrogates immunosuppressive activity of myeloid-derived suppressor cells from prostate cancer patients DMS Hossain, SK Pal, D Moreira, P Duttagupta, Q Zhang, H Won, J Jones, ... Clinical Cancer Research 21 (16), 3771-3782, 2015 | 190 | 2015 |
Stat3 activity in melanoma cells affects migration of immune effector cells and nitric oxide-mediated antitumor effects L Burdelya, M Kujawski, G Niu, B Zhong, T Wang, S Zhang, M Kortylewski, ... The Journal of Immunology 174 (7), 3925-3931, 2005 | 180 | 2005 |
Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1 M Kortylewski, PC Heinrich, A Mackiewicz, U Schniertshauer, ... Oncogene 18 (25), 3742-3753, 1999 | 176 | 1999 |
STING pathway activation stimulates potent immunity against acute myeloid leukemia E Curran, X Chen, L Corrales, DE Kline, TW Dubensky, P Duttagupta, ... Cell reports 15 (11), 2357-2366, 2016 | 168 | 2016 |