Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease. MT Grande, B Sánchez-Laorden, C López-Blau, CA De Frutos, A Boutet, ... Nat Med 21 (9), 989-97, 2015 | 724 | 2015 |
Melanocortin‐1 receptor structure and functional regulation JC García‐Borrón, BL Sánchez‐Laorden, C Jiménez‐Cervantes Pigment cell research 18 (6), 393-410, 2005 | 480 | 2005 |
Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma MR Girotti, M Pedersen, B Sanchez-Laorden, A Viros, S Turajlic, ... Cancer discovery 3 (2), 158-167, 2013 | 412 | 2013 |
Ultraviolet radiation accelerates BRAF-driven melanomagenesis by targeting TP53 A Viros, B Sanchez-Laorden, M Pedersen, SJ Furney, J Rae, K Hogan, ... Nature 511 (7510), 478-482, 2014 | 268 | 2014 |
Oncogenic BRAF induces melanoma cell invasion by downregulating the cGMP-specific phosphodiesterase PDE5A I Arozarena, B Sanchez-Laorden, L Packer, C Hidalgo-Carcedo, ... Cancer cell 19 (1), 45-57, 2011 | 237 | 2011 |
Paradox-breaking RAF inhibitors that also target SRC are effective in drug-resistant BRAF mutant melanoma MR Girotti, F Lopes, N Preece, D Niculescu-Duvaz, A Zambon, L Davies, ... Cancer cell 27 (1), 85-96, 2015 | 231 | 2015 |
The immune microenvironment confers resistance to MAPK pathway inhibitors through macrophage-derived TNFα MP Smith, B Sanchez-Laorden, K O'Brien, H Brunton, J Ferguson, ... Cancer discovery 4 (10), 1214-1229, 2014 | 213 | 2014 |
Diverse matrix metalloproteinase functions regulate cancer amoeboid migration JL Orgaz, P Pandya, R Dalmeida, P Karagiannis, B Sanchez-Laorden, ... Nature communications 5 (1), 4255, 2014 | 200 | 2014 |
BRAF inhibitors induce metastasis in RAS mutant or inhibitor-resistant melanoma cells by reactivating MEK and ERK signaling B Sanchez-Laorden, A Viros, MR Girotti, M Pedersen, G Saturno, ... Science signaling 7 (318), ra30-ra30, 2014 | 147 | 2014 |
Dimerization of the human melanocortin 1 receptor: functional consequences and dominant-negative effects BL Sánchez-Laorden, J Sánchez-Más, E Martínez-Alonso, ... Journal of investigative dermatology 126 (1), 172-181, 2006 | 109 | 2006 |
Ultraviolet radiation–induced DNA damage is prognostic for outcome in melanoma LD Trucco, PA Mundra, K Hogan, P Garcia-Martinez, A Viros, AK Mandal, ... Nature medicine 25 (2), 221-224, 2019 | 107 | 2019 |
Regulation of human melanocortin 1 receptor signaling and trafficking by Thr-308 and Ser-316 and its alteration in variant alleles associated with red hair and skin cancer BL Sanchez-Laorden, C Jimenez-Cervantes, JC Garcia-Borron Journal of Biological Chemistry 282 (5), 3241-3251, 2007 | 71 | 2007 |
Primary Melanoma of the CNS in Children Is Driven by Congenital Expression of Oncogenic NRAS in Melanocytes M Pedersen, HVN Küsters-Vandevelde, A Viros, PJTA Groenen, ... Cancer discovery 3 (4), 458-469, 2013 | 70 | 2013 |
Aberrant trafficking of human melanocortin 1 receptor variants associated with red hair and skin cancer: Steady‐state retention of mutant forms in the proximal golgi BL Sánchez‐Laorden, C Herraiz, JC Valencia, VJ Hearing, ... Journal of cellular physiology 220 (3), 640-654, 2009 | 55 | 2009 |
The melanocortin-1 receptor carboxyl terminal pentapeptide is essential for MC1R function and expression on the cell surface J Sanchez-Mas, BL Sanchez-Laorden, LA Guillo, C Jimenez-Cervantes, ... Peptides 26 (10), 1848-1857, 2005 | 54 | 2005 |
Mechanism of dimerization of the human melanocortin 1 receptor PT Zanna, BL Sánchez-Laorden, AB Pérez-Oliva, MC Turpín, C Herraiz, ... Biochemical and biophysical research communications 368 (2), 211-216, 2008 | 44 | 2008 |
Inhibiting EGF receptor or SRC family kinase signaling overcomes BRAF inhibitor resistance in melanoma. Cancer Discov. 2013; 3: 158–167. doi: 10.1158/2159-8290 MR Girotti, M Pedersen, B Sanchez-Laorden, A Viros, S Turajlic, ... CD-12-0386.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 41 | |
Differential and competitive regulation of human melanocortin 1 receptor signaling by β-arrestin isoforms M Abrisqueta, C Herraiz, AB Perez Oliva, BL Sanchez-Laorden, ... Journal of cell science 126 (16), 3724-3737, 2013 | 37 | 2013 |
Mind the IQGAP B Sanchez-Laorden, A Viros, R Marais Cancer cell 23 (6), 715-717, 2013 | 36 | 2013 |
Variant amino acids in different domains of the human melanocortin 1 receptor impair cell surface expression. BL Sanchez-Laorden, J Sanchez-Mas, MC Turpin, JC Garcia-Borron, ... Cellular and Molecular Biology (Noisy-le-Grand, France) 52 (2), 39-46, 2006 | 28 | 2006 |