Bistability, epigenetics, and bet-hedging in bacteria JW Veening, WK Smits, OP Kuipers Annu. Rev. Microbiol. 62 (1), 193-210, 2008 | 1204 | 2008 |
PrimeView Clostridium difficile infection WK Smits, D Lyras, DB Lacy, MH Wilcox, EJ Kuijper Nature Reviews Disease Primers 16021, 1, 2016 | 875* | 2016 |
Clostridium difficile infection WK Smits, D Lyras, DB Lacy, MH Wilcox, EJ Kuijper Nature Reviews Disease Primers 16020, 1-20, 2016 | 875 | 2016 |
Phenotypic variation in bacteria: the role of feedback regulation WK Smits, OP Kuipers, JW Veening Nature Reviews Microbiology 4 (4), 259-271, 2006 | 619 | 2006 |
Stripping Bacillus: ComK auto‐stimulation is responsible for the bistable response in competence development WK Smits, CC Eschevins, KA Susanna, S Bron, OP Kuipers, LW Hamoen Molecular microbiology 56 (3), 604-614, 2005 | 257 | 2005 |
Functional genomics reveals that Clostridium difficileSpo0A coordinates sporulation, virulence and metabolism LJ Pettit, HP Browne, L Yu, WK Smits, RP Fagan, L Barquist, MJ Martin, ... BMC genomics 15, 1-15, 2014 | 165 | 2014 |
Improving the predictive value of the competence transcription factor (ComK) binding site in Bacillus subtilis using a genomic approach LW Hamoen, WK Smits, A Jong, S Holsappel, OP Kuipers Nucleic acids research 30 (24), 5517-5528, 2002 | 165 | 2002 |
The Transcriptional Regulator Rok Binds A+T-Rich DNA and Is Involved in Repression of a Mobile Genetic Element in Bacillus subtilis WK Smits, AD Grossman PLoS genetics 6 (11), e1001207, 2010 | 125 | 2010 |
Genome2D: a visualization tool for the rapid analysis of bacterial transcriptome data RJS Baerends, WK Smits, A de Jong, LW Hamoen, J Kok, OP Kuipers Genome Biology 5, 1-6, 2004 | 123 | 2004 |
Mechanistic Insights in the Success of Fecal Microbiota Transplants for the Treatment of Clostridium difficile Infections A Baktash, EM Terveer, RD Zwittink, BVH Hornung, J Corver, EJ Kuijper, ... Frontiers in microbiology 9, 1242, 2018 | 110 | 2018 |
TcdC Does Not Significantly Repress Toxin Expression in Clostridium difficile 630ΔErm D Bakker, WK Smits, EJ Kuijper, J Corver Public Library of Science 7 (8), e43247, 2012 | 107 | 2012 |
Plasmid-mediated metronidazole resistance in Clostridioides difficile IM Boekhoud, BVH Hornung, E Sevilla, C Harmanus, IMJG Bos-Sanders, ... Nature communications 11 (1), 598, 2020 | 105 | 2020 |
The Rok Protein of Bacillus subtilis Represses Genes for Cell Surface and Extracellular Functions M Albano, WK Smits, LTY Ho, B Kraigher, I Mandic-Mulec, OP Kuipers, ... Journal of bacteriology 187 (6), 2010-2019, 2005 | 105 | 2005 |
Temporal separation of distinct differentiation pathways by a dual specificity Rap‐Phr system in Bacillus subtilis WK Smits, C Bongiorni, JW Veening, LW Hamoen, OP Kuipers, M Perego Molecular microbiology 65 (1), 103-120, 2007 | 101 | 2007 |
C. difficile 630Δerm Spo0A regulates sporulation, but does not contribute to toxin production, by direct high-affinity binding to target DNA KE Rosenbusch, D Bakker, EJ Kuijper, WK Smits PloS one 7 (10), e48608, 2012 | 99 | 2012 |
DNA replication proteins as potential targets for antimicrobials in drug-resistant bacterial pathogens E van Eijk, B Wittekoek, EJ Kuijper, WK Smits Journal of Antimicrobial Chemotherapy 72 (5), 1275-1284, 2017 | 95 | 2017 |
Single cell analysis of gene expression patterns of competence development and initiation of sporulation in Bacillus subtilis grown on chemically defined media JW Veening, WK Smits, LW Hamoen, OP Kuipers Journal of applied microbiology 101 (3), 531-541, 2006 | 92 | 2006 |
Ordered association of helicase loader proteins with the Bacillus subtilis origin of replication in vivo WK Smits, AI Goranov, AD Grossman Molecular microbiology 75 (2), 452-461, 2010 | 87 | 2010 |
Interspecies interactions between Clostridium difficile and Candida albicans PT van Leeuwen, JM van der Peet, FJ Bikker, MA Hoogenkamp, ... Msphere 1 (6), 10.1128/msphere. 00187-16, 2016 | 79 | 2016 |
Complete genome sequence of the Clostridium difficile laboratory strain 630Δ erm reveals differences from strain 630, including translocation of the mobile element CTn 5 E Van Eijk, SY Anvar, HP Browne, WY Leung, J Frank, AM Schmitz, ... BMC genomics 16, 1-14, 2015 | 79 | 2015 |