Detection of β2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET) S Angers, A Salahpour, E Joly, S Hilairet, D Chelsky, M Dennis, M Bouvier Proceedings of the National Academy of Sciences 97 (7), 3684-3689, 2000 | 1045 | 2000 |
A peptide derived from a β2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation TE Hebert, S Moffett, JP Morello, TP Loisel, DG Bichet, C Barret, ... Journal of Biological Chemistry 271 (27), 16384-16392, 1996 | 999 | 1996 |
Oligomerization of G-protein-coupled transmitter receptors M Bouvier Nature Reviews Neuroscience 2 (4), 274-286, 2001 | 869 | 2001 |
Palmitoylation of the human β2-adrenergic receptor: mutation of Cys341 in the carboxyl tail leads to an uncoupled nonpalmitoylated form of the receptor BF O'dowd, M Hnatowich, MG Caron, RJ Lefkowitz, M Bouvier Journal of Biological Chemistry 264 (13), 7564-7569, 1989 | 794 | 1989 |
Roles of G‐protein‐coupled receptor dimerization: From ontogeny to signalling regulation S Terrillon, M Bouvier EMBO reports 5 (1), 30-34, 2004 | 785 | 2004 |
DIMERIZATION: An Emerging Concept for G Protein–Coupled Receptor Ontogeny and Function S Angers, A Salahpour, M Bouvier Annual review of pharmacology and toxicology 42 (1), 409-435, 2002 | 746 | 2002 |
Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants JP Morello, A Salahpour, A Laperrière, V Bernier, MF Arthus, M Lonergan, ... The Journal of clinical investigation 105 (7), 887-895, 2000 | 651 | 2000 |
β-Arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors M Azzi, PG Charest, S Angers, G Rousseau, T Kohout, M Bouvier, ... Proceedings of the National Academy of Sciences 100 (20), 11406-11411, 2003 | 641 | 2003 |
Cross-talk between cellular signalling pathways suggested by phorbol-ester-induced adenylate cyclase phosphorylation T Yoshimasa, DR Sibley, M Bouvier, RJ Lefkowitz, MG Caron Nature 327 (6117), 67-70, 1987 | 632 | 1987 |
Quantitative assessment of β1-and β2-adrenergic receptor homo-and heterodimerization by bioluminescence resonance energy transfer JF Mercier, A Salahpour, S Angers, A Breit, M Bouvier Journal of Biological Chemistry 277 (47), 44925-44931, 2002 | 602 | 2002 |
Removal of phosphorylation sites from the β2-adrenergic receptor delays onset of agonist-promoted desensitization M Bouvier, WP Hausdorff, AD Blasi, BF O'Dowd, BK Kobilka, MG Caron, ... Nature 333 (6171), 370-373, 1988 | 598 | 1988 |
Phosphorylation sites on two domains of the β2-adrenergic receptor are involved in distinct pathways of receptor desensitization WP Hausdorff, M Bouvier, BF O'dowd, GP Irons, MG Caron, RJ Lefkowitz Journal of Biological Chemistry 264 (21), 12657-12665, 1989 | 581 | 1989 |
Adenosine A2A-dopamine D2 receptor-receptor heteromerization: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer M Canals, D Marcellino, F Fanelli, F Ciruela, P De Benedetti, ... Journal of Biological Chemistry 278 (47), 46741-46749, 2003 | 565 | 2003 |
Regulation of adenylyl cyclase-coupled beta-adrenergic receptors JL Benovic, M Bouvier, MG Caron, RJ Lefkowitz Annual review of cell biology 4 (1), 405-428, 1988 | 563 | 1988 |
Emerging role of homo-and heterodimerization in G-protein-coupled receptor biosynthesis and maturation S Bulenger, S Marullo, M Bouvier Trends in pharmacological sciences 26 (3), 131-137, 2005 | 553 | 2005 |
Probing the activation-promoted structural rearrangements in preassembled receptor–G protein complexes C Galés, JJJ Van Durm, S Schaak, S Pontier, Y Percherancier, M Audet, ... Nature structural & molecular biology 13 (9), 778-786, 2006 | 545 | 2006 |
GPCR-G protein-β-arrestin super-complex mediates sustained G protein signaling ARB Thomsen, B Plouffe, TJ Cahill, AK Shukla, JT Tarrasch, AM Dosey, ... Cell 166 (4), 907-919, 2016 | 543 | 2016 |
Inverse agonist activity of beta-adrenergic antagonists. P Chidiac, TE Hebert, M Valiquette, M Dennis, M Bouvier Molecular pharmacology 45 (3), 490-499, 1994 | 514 | 1994 |
Real-time monitoring of receptor and G-protein interactions in living cells C Gales, RV Rebois, M Hogue, P Trieu, A Breit, TE Hébert, M Bouvier Nature methods 2 (3), 177-184, 2005 | 487 | 2005 |
Building a new conceptual framework for receptor heteromers S Ferré, R Baler, M Bouvier, MG Caron, LA Devi, T Durroux, K Fuxe, ... Nature chemical biology 5 (3), 131-134, 2009 | 476 | 2009 |