Global analysis of biosynthetic gene clusters reveals vast potential of secondary metabolite production in Penicillium species JC Nielsen, S Grijseels, S Prigent, B Ji, J Dainat, KF Nielsen, JC Frisvad, ... Nature Microbiology 2, 17044, 2017 | 266 | 2017 |
Hepatic transcriptome signatures in patients with varying degrees of nonalcoholic fatty liver disease compared with healthy normal-weight individuals MP Suppli, KTG Rigbolt, SS Veidal, S Heebøll, PL Eriksen, M Demant, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 316 (4 …, 2019 | 189 | 2019 |
Development of fungal cell factories for the production of secondary metabolites: Linking genomics and metabolism JC Nielsen, J Nielsen Synthetic and Systems Biotechnology 2 (1), 5-12, 2017 | 115 | 2017 |
Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source ML Boland, D Oró, KS Tølbøl, ST Thrane, JC Nielsen, TS Cohen, ... World journal of gastroenterology 25 (33), 4904, 2019 | 99 | 2019 |
Pathway engineering in yeast for synthesizing the complex polyketide bikaverin M Zhao, Y Zhao, M Yao, H Iqbal, Q Hu, H Liu, B Qiao, C Li, ... Nature communications 11 (1), 6197, 2020 | 53 | 2020 |
Combined obeticholic acid and elafibranor treatment promotes additive liver histological improvements in a diet-induced ob/ob mouse model of biopsy-confirmed … JD Roth, SS Veidal, LKD Fensholdt, KTG Rigbolt, R Papazyan, ... Scientific reports 9 (1), 9046, 2019 | 43 | 2019 |
Penicillium arizonense, a new, genome sequenced fungal species, reveals a high chemical diversity in secreted metabolites S Grijseels, JC Nielsen, M Randelovic, J Nielsen, KF Nielsen, M Workman, ... Scientific Reports 6 (1), 35112, 2016 | 40 | 2016 |
Physiological characterization of secondary metabolite producing Penicillium cell factories S Grijseels, JC Nielsen, J Nielsen, TO Larsen, JC Frisvad, KF Nielsen, ... Fungal Biology and Biotechnology 4 (1), 8, 2017 | 38 | 2017 |
Identification of the decumbenone biosynthetic gene cluster in Penicillium decumbens and the importance for production of calbistrin S Grijseels, C Pohl, JC Nielsen, Z Wasil, Y Nygård, J Nielsen, JC Frisvad, ... Fungal Biology and Biotechnology 5, 1-17, 2018 | 28 | 2018 |
Reconstruction of 24 Penicillium genome‐scale metabolic models shows diversity based on their secondary metabolism S Prigent, JC Nielsen, JC Frisvad, J Nielsen Biotechnology and Bioengineering 115 (10), 2604-2612, 2018 | 25 | 2018 |
Industrial antifoam agents impair ethanol fermentation and induce stress responses in yeast cells JC Nielsen, F Senne de Oliveira Lino, TG Rasmussen, J Thykær, ... Applied microbiology and biotechnology 101, 8237-8248, 2017 | 23 | 2017 |
Impact of sex on diabetic nephropathy and the renal transcriptome in UNx db/db C57BLKS mice FE Sembach, LN Fink, T Johansen, BB Boland, T Secher, ST Thrane, ... Physiological Reports 7 (24), e14333, 2019 | 20 | 2019 |
Peptide-YY3-36/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic β-cell function and … BB Boland, RC Laker, S O'Brien, S Sitaula, I Sermadiras, JC Nielsen, ... Molecular metabolism 55, 101392, 2022 | 16 | 2022 |
The dorsomedial hypothalamus and nucleus of the solitary tract as key regulators in a rat model of chronic obesity C Zhang, P Barkholt, JC Nielsen, DD Thorbek, K Rigbolt, N Vrang, ... Brain research 1727, 146538, 2020 | 14 | 2020 |
Comparative transcriptome analysis shows conserved metabolic regulation during production of secondary metabolites in filamentous fungi JC Nielsen, S Prigent, S Grijseels, M Workman, B Ji, J Nielsen Msystems 4 (2), 10.1128/msystems. 00012-19, 2019 | 14 | 2019 |
Unlocking the potential of fungi: the QuantFung project Z Büttel, R Díaz, B Dirnberger, M Flak, S Grijseels, MJ Kwon, JCF Nielsen, ... Fungal Biology and Biotechnology 2, 1-6, 2015 | 8 | 2015 |
Integrative transcriptomic profiling of a mouse model of hypertension-accelerated diabetic kidney disease FE Sembach, HM Ægidius, LN Fink, T Secher, A Aarup, J Jelsing, ... Disease models & mechanisms 14 (10), dmm049086, 2021 | 7 | 2021 |
Systems Biology of the Secondary Metabolism in Filamentous Fungi JC Nielsen PQDT-Global, 2018 | 4 | 2018 |
Correction to: Industrial antifoam agents impair ethanol fermentation and induce stress responses in yeast cells JC Nielsen, FSO Lino, TG Rasmussen, J Thykær, CT Workman, TO Basso Applied microbiology and biotechnology 102, 513-513, 2018 | | 2018 |