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Qiang Cheng (程强)
Qiang Cheng (程强)
College of Future Technology, Peking University
在 pku.edu.cn 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR–Cas gene editing
Q Cheng, T Wei, L Farbiak, LT Johnson, SA Dilliard, DJ Siegwart
Nature nanotechnology 15 (4), 313-320, 2020
11452020
Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing
T Wei, Q Cheng (Co-First), YL Min, EN Olson, DJ Siegwart
Nature communications 11 (1), 1-12, 2020
4372020
On the mechanism of tissue-specific mRNA delivery by selective organ targeting nanoparticles
SA Dilliard, Q Cheng, DJ Siegwart
Proceedings of the national academy of sciences 118 (52), e2109256118, 2021
3742021
Anticancer drug nanomicelles formed by self-assembling amphiphilic dendrimer to combat cancer drug resistance
T Wei, C Chen, J Liu, C Liu, P Posocco, X Liu, Q Cheng, S Huo, Z Liang, ...
Proceedings of the National Academy of Sciences 112 (10), 2978-2983, 2015
3732015
Membrane-destabilizing ionizable phospholipids for organ-selective mRNA delivery and CRISPR–Cas gene editing
S Liu, Q Cheng, T Wei, X Yu, LT Johnson, L Farbiak, DJ Siegwart
Nature materials 20 (5), 701-710, 2021
3332021
Adaptive amphiphilic dendrimer‐based nanoassemblies as robust and versatile siRNA delivery systems
X Liu, J Zhou, T Yu, C Chen, Q Cheng, K Sengupta, Y Huang, H Li, C Liu, ...
Angewandte Chemie International Edition 53 (44), 11822-11827, 2014
2092014
Functionalized nanoscale micelles improve drug delivery for cancer therapy in vitro and in vivo
T Wei, J Liu, H Ma, Q Cheng, Y Huang, J Zhao, S Huo, X Xue, Z Liang, ...
Nano letters 13 (6), 2528-2534, 2013
1862013
Dendrimer‐based lipid nanoparticles deliver therapeutic FAH mRNA to normalize liver function and extend survival in a mouse model of hepatorenal tyrosinemia type I
Q Cheng, T Wei, Y Jia, L Farbiak, K Zhou, S Zhang, Y Wei, H Zhu, ...
Advanced materials 30 (52), 1805308, 2018
1762018
Preparation of selective organ-targeting (SORT) lipid nanoparticles (LNPs) using multiple technical methods for tissue-specific mRNA delivery
X Wang, S Liu, Y Sun, X Yu, SM Lee, Q Cheng, T Wei, J Gong, ...
Nature protocols 18 (1), 265-291, 2023
1482023
Membrane‐destabilizing ionizable lipid empowered imaging‐guided siRNA delivery and cancer treatment
S Guo, K Li, B Hu, C Li, M Zhang, A Hussain, X Wang, Q Cheng, F Yang, ...
Exploration 1 (1), 35-49, 2021
1262021
Intracellular cleavable poly (2-dimethylaminoethyl methacrylate) functionalized mesoporous silica nanoparticles for efficient siRNA delivery in vitro and in vivo
D Lin, Q Cheng (Co-first author), Q Jiang, Y Huang, Z Yang, S Han, ...
Nanoscale 5 (10), 4291-4301, 2013
1112013
Enhanced endosomal/lysosomal escape by distearoyl phosphoethanolamine-polycarboxybetaine lipid for systemic delivery of siRNA
Y Li, Q Cheng (Co-first author), Q Jiang, Y Huang, H Liu, Y Zhao, W Cao, ...
Journal of Controlled Release 176, 104-114, 2014
1082014
Systemic mRNA delivery to the lungs by functional polyester-based carriers
Y Yan, H Xiong, X Zhang, Q Cheng, DJ Siegwart
Biomacromolecules 18 (12), 4307-4315, 2017
972017
Mastering dendrimer self‐assembly for efficient siRNA delivery: from conceptual design to in vivo efficient gene silencing
C Chen, P Posocco, X Liu, Q Cheng, E Laurini, J Zhou, C Liu, Y Wang, ...
Small 12 (27), 3667-3676, 2016
932016
Zwitterionic phospholipidation of cationic polymers facilitates systemic mRNA delivery to spleen and lymph nodes
S Liu, X Wang, X Yu, Q Cheng, LT Johnson, S Chatterjee, D Zhang, ...
Journal of the American Chemical Society 143 (50), 21321-21330, 2021
892021
The promising nanocarrier for doxorubicin and siRNA co-delivery by PDMAEMA-based amphiphilic nanomicelles
Q Cheng, L Du, L Meng, S Han, T Wei, X Wang, Y Wu, X Song, J Zhou, ...
ACS applied materials & interfaces 8 (7), 4347-4356, 2016
892016
Gene transfection efficacy and biocompatibility of polycation/DNA complexes coated with enzyme degradable PEGylated hyaluronic acid
W Zhang, Q Cheng (Co-first author), S Guo, D Lin, P Huang, J Liu, T Wei, ...
Biomaterials 34 (27), 6495-6503, 2013
882013
Delivery of Tissue-Targeted Scalpels: Opportunities and Challenges for In Vivo CRISPR/Cas-Based Genome Editing
T Wei, Q Cheng, L Farbiak, DG Anderson, R Langer, DJ Siegwart
ACS nano 14 (8), 9243-9262, 2020
832020
A systematic study of unsaturation in lipid nanoparticles leads to improved mRNA transfection in vivo
SM Lee, Q Cheng, X Yu, S Liu, LT Johnson, DJ Siegwart
Angewandte Chemie 133 (11), 5912-5917, 2021
822021
pH-sensitive nanomicelles for high-efficiency siRNA delivery in vitro and in vivo: an insight into the design of polycations with robust cytosolic release
J Zhou, Y Wu, C Wang, Q Cheng, S Han, X Wang, J Zhang, L Deng, ...
Nano letters 16 (11), 6916-6923, 2016
752016
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