Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial S Vermeire, S O'Byrne, M Keir, M Williams, TT Lu, JC Mansfield, CA Lamb, ... The Lancet 384 (9940), 309-318, 2014 | 508 | 2014 |
JAK–STAT pathway targeting for the treatment of inflammatory bowel disease A Salas, C Hernandez-Rocha, M Duijvestein, W Faubion, D McGovern, ... Nature reviews Gastroenterology & hepatology 17 (6), 323-337, 2020 | 433 | 2020 |
The primacy of affinity over clustering in regulation of adhesiveness of the integrin αLβ2 M Kim, CV Carman, W Yang, A Salas, TA Springer The Journal of cell biology 167 (6), 1241-1253, 2004 | 302 | 2004 |
Endothelial cells proactively form microvilli-like membrane projections upon intercellular adhesion molecule 1 engagement of leukocyte LFA-1 CV Carman, CD Jun, A Salas, TA Springer The Journal of Immunology 171 (11), 6135-6144, 2003 | 276 | 2003 |
Rolling adhesion through an extended conformation of integrin αLβ2 and relation to α I and β I-like domain interaction A Salas, M Shimaoka, AN Kogan, C Harwood, UH von Andrian, ... Immunity 20 (4), 393-406, 2004 | 265 | 2004 |
Transcriptional analysis of the intestinal mucosa of patients with ulcerative colitis in remission reveals lasting epithelial cell alterations N Planell, JJ Lozano, R Mora-Buch, MC Masamunt, M Jimeno, I Ordás, ... Gut 62 (7), 967-976, 2013 | 254 | 2013 |
VCAM-1, but not ICAM-1 or MAdCAM-1, immunoblockade ameliorates DSS-induced colitis in mice A Soriano, A Salas, A Salas, M Sans, M Gironella, M Elena, DC Anderson, ... Laboratory investigation 80 (10), 1541-1551, 2000 | 220 | 2000 |
Bistable regulation of integrin adhesiveness by a bipolar metal ion cluster JF Chen, A Salas, TA Springer Nature Structural & Molecular Biology 10 (12), 995-1001, 2003 | 212 | 2003 |
CD1d function is regulated by microsomal triglyceride transfer protein S Brozovic, T Nagaishi, M Yoshida, S Betz, A Salas, D Chen, A Kaser, ... Nature medicine 10 (5), 535-539, 2004 | 208 | 2004 |
Alterations in the epithelial stem cell compartment could contribute to permanent changes in the mucosa of patients with ulcerative colitis I Dotti, R Mora-Buch, E Ferrer-Picón, N Planell, P Jung, MC Masamunt, ... Gut 66 (12), 2069-2079, 2017 | 195 | 2017 |
Heparin attenuates TNF-α induced inflammatory response through a CD11b dependent mechanism A Salas, M Sans, A Soriano, JC Reverter, DC Anderson, JM Pique, ... Gut 47 (1), 88-96, 2000 | 189 | 2000 |
Microsomal triglyceride transfer protein lipidation and control of CD1d on antigen-presenting cells SK Dougan, A Salas, P Rava, A Agyemang, A Kaser, J Morrison, ... The Journal of experimental medicine 202 (4), 529-539, 2005 | 185 | 2005 |
Small molecule integrin antagonists that bind to the β2 subunit I-like domain and activate signals in one direction and block them in the other M Shimaoka, A Salas, W Yang, G Weitz-Schmidt, TA Springer Immunity 19 (3), 391-402, 2003 | 157 | 2003 |
Importance of force linkage in mechanochemistry of adhesion receptors NS Astrof, A Salas, M Shimaoka, JF Chen, TA Springer Biochemistry 45 (50), 15020-15028, 2006 | 156 | 2006 |
Effects of steroid treatment on activation of nuclear factor κB in patients with inflammatory bowel disease E Ardite, J Panes, M Miranda, A Salas, JI Elizalde, M Sans, Y Arce, ... British journal of pharmacology 124 (3), 431-433, 1998 | 149 | 1998 |
Identification of inflammatory mediators in patients with Crohn's disease unresponsive to anti-TNFα therapy RF Leal, N Planell, R Kajekar, JJ Lozano, I Ordás, I Dotti, M Esteller, ... Gut 64 (2), 233-242, 2015 | 146 | 2015 |
Role of P-selectin and ICAM-1 in pancreatitis-induced lung inflammation in rats: significance of oxidative stress E Folch, A Salas, J Panés, E Gelpí, J Roselló-Catafau, DC Anderson, ... Annals of surgery 230 (6), 792, 1999 | 126 | 1999 |
Transition from rolling to firm adhesion is regulated by the conformation of the I domain of the integrin lymphocyte function-associated antigen-1 A Salas, M Shimaoka, S Chen, CV Carman, T Springer Journal of Biological Chemistry 277 (52), 50255-50262, 2002 | 125 | 2002 |
Intersubunit signal transmission in integrins by a receptor-like interaction with a pull spring W Yang, M Shimaoka, A Salas, J Takagi, TA Springer Proceedings of the National Academy of Sciences 101 (9), 2906-2911, 2004 | 124 | 2004 |
A gut microbial mimic that hijacks diabetogenic autoreactivity to suppress colitis RH Nanjundappa, F Ronchi, J Wang, X Clemente-Casares, ... Cell 171 (3), 655-667. e17, 2017 | 115 | 2017 |