Context-specific regulation of NF-κB target gene expression by EZH2 in breast cancers ST Lee, Z Li, Z Wu, M Aau, P Guan, RKM Karuturi, YC Liou, Q Yu Molecular cell 43 (5), 798-810, 2011 | 449 | 2011 |
Genome-wide mutational signatures of aristolochic acid and its application as a screening tool SL Poon, ST Pang, JR McPherson, W Yu, KK Huang, P Guan, WH Weng, ... Science translational medicine 5 (197), 197ra101-197ra101, 2013 | 319 | 2013 |
Structural variation detection using next-generation sequencing data: a comparative technical review P Guan, WK Sung Methods 102, 36-49, 2016 | 171 | 2016 |
PDK1 signaling toward PLK1–MYC activation confers oncogenic transformation, tumor-initiating cell activation, and resistance to mTOR-targeted therapy J Tan, Z Li, PL Lee, P Guan, MY Aau, ST Lee, M Feng, CZ Lim, EYJ Lee, ... Cancer discovery 3 (10), 1156-1171, 2013 | 155* | 2013 |
Recurrent fusion genes in gastric cancer: CLDN18-ARHGAP26 induces loss of epithelial integrity F Yao, JP Kausalya, YY Sia, ASM Teo, WH Lee, AGM Ong, Z Zhang, ... Cell reports 12 (2), 272-285, 2015 | 149 | 2015 |
The spatial organization of intra-tumour heterogeneity and evolutionary trajectories of metastases in hepatocellular carcinoma W Zhai, TKH Lim, T Zhang, ST Phang, Z Tiang, P Guan, MH Ng, JQ Lim, ... Nature communications 8 (1), 4565, 2017 | 141 | 2017 |
VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma X Yao, J Tan, KJ Lim, J Koh, WF Ooi, Z Li, D Huang, M Xing, YS Chan, ... Cancer discovery 7 (11), 1284-1305, 2017 | 137 | 2017 |
Protein tyrosine phosphatase UBASH3B is overexpressed in triple-negative breast cancer and promotes invasion and metastasis ST Lee, M Feng, Y Wei, Z Li, Y Qiao, P Guan, X Jiang, CH Wong, K Huynh, ... Proceedings of the National Academy of Sciences 110 (27), 11121-11126, 2013 | 79 | 2013 |
Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma JY Chan, JQ Lim, J Yeong, V Ravi, P Guan, A Boot, TKY Tay, ... The Journal of clinical investigation 130 (11), 5833-5846, 2020 | 77 | 2020 |
Genomic characterisation of breast fibroepithelial lesions in an international cohort ND Md Nasir, CCY Ng, V Rajasegaran, SF Wong, W Liu, GXP Ng, JY Lee, ... The Journal of pathology 249 (4), 447-460, 2019 | 39 | 2019 |
MED12, TERT and RARA in fibroepithelial tumours of the breast HY Chang, VCY Koh, NDM Nasir, CCY Ng, P Guan, AA Thike, BT Teh, ... Journal of Clinical Pathology 73 (1), 51-56, 2020 | 35 | 2020 |
Genomic profile of breast sarcomas: a comparison with malignant phyllodes tumours SZ Lim, CCY Ng, V Rajasegaran, P Guan, S Selvarajan, AA Thike, ... Breast Cancer Research and Treatment 174, 365-373, 2019 | 26 | 2019 |
Targeting the IRAK1–S100A9 Axis Overcomes Resistance to Paclitaxel in Nasopharyngeal Carcinoma L Liu, S Liu, P Deng, Y Liang, R Xiao, LQ Tang, J Chen, QY Chen, P Guan, ... Cancer Research 81 (5), 1413-1425, 2021 | 24 | 2021 |
Genetic differences between benign phyllodes tumors and fibroadenomas revealed through targeted next generation sequencing CCY Ng, NDM Nasir, BN Loke, TKY Tay, AA Thike, V Rajasegaran, W Liu, ... Modern Pathology 34 (7), 1320-1332, 2021 | 23 | 2021 |
A novel genomic panel as an adjunctive diagnostic tool for the characterization and profiling of breast Fibroepithelial lesions Y Sim, GXP Ng, CCY Ng, V Rajasegaran, SF Wong, W Liu, P Guan, ... BMC Medical Genomics 12, 1-14, 2019 | 23 | 2019 |
Functional characterization of D9, a novel deazaneplanocin A (DZNep) analog, in targeting acute myeloid leukemia (AML) X Jiang, CZH Lim, Z Li, PL Lee, SMJM Yatim, P Guan, J Li, J Zhou, J Pan, ... PloS one 10 (4), e0122983, 2015 | 22 | 2015 |
Morphologic and genetic heterogeneity in breast fibroepithelial lesions—a comprehensive mapping study BY Tan, NDM Nasir, HY Chang, CCY Ng, P Guan, S Nagarajan, ... Modern Pathology 33 (9), 1732-1745, 2020 | 18 | 2020 |
Mutational signatures in mandibular ameloblastoma correlate with smoking P Guan, SF Wong, JQ Lim, CCY Ng, PL Soong, CQX Sim, CK Ong, ... Journal of dental research 98 (6), 652-658, 2019 | 16 | 2019 |
RAD21 amplification epigenetically suppresses interferon signaling to promote immune evasion in ovarian cancer P Deng, Z Wang, J Chen, S Liu, X Yao, S Liu, L Liu, Z Yu, Y Huang, ... The Journal of Clinical Investigation 132 (22), 2022 | 14 | 2022 |
Molecular insights into paediatric breast fibroepithelial tumours TKY Tay, P Guan, BN Loke, NDM Nasir, V Rajasegaran, AA Thike, D Lian, ... Histopathology 73 (5), 809-818, 2018 | 14 | 2018 |