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Bryan Ng
Bryan Ng
Scientist, Agency for Science, Technology and Research
在 sics.a-star.edu.sg 的电子邮件经过验证
标题
引用次数
引用次数
年份
Reversal of phenotypic abnormalities by CRISPR/Cas9-mediated gene correction in Huntington disease patient-derived induced pluripotent stem cells
X Xu, Y Tay, B Sim, SI Yoon, Y Huang, J Ooi, KH Utami, A Ziaei, B Ng, ...
Stem cell reports 8 (3), 619-633, 2017
2232017
Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson’s iPSC-dopamine neurons
DA Beccano-Kelly, M Cherubini, Y Mousba, KML Cramb, S Giussani, ...
Iscience 26 (7), 2023
142023
Neurons derived from individual early Alzheimer’s disease patients reflect their clinical vulnerability
B Ng, HA Rowland, T Wei, K Arunasalam, EM Hayes, I Koychev, ...
Brain Communications 4 (6), fcac267, 2022
132022
pS421 huntingtin modulates mitochondrial phenotypes and confers neuroprotection in an HD hiPSC model
X Xu, B Ng, B Sim, CI Radulescu, NABM Yusof, WI Goh, S Lin, JSY Lim, ...
Cell Death & Disease 11 (9), 809, 2020
122020
Tau depletion in human neurons mitigates Aβ-driven toxicity
B Ng, J Vowles, F Bertherat, A Abey, P Kilfeather, D Beccano-Kelly, ...
Molecular Psychiatry, 1-12, 2024
82024
Early deficits in an in vitro striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation
QB Do, H Noor, R Marquez-Gomez, KML Cramb, B Ng, A Abbey, ...
npj Parkinson's Disease 10 (1), 82, 2024
22024
Early striatal hyperexcitability in an in vitro human striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation
QB Do, B Ng, RM Gomez, D Beccano-Kelly, N Ibarra-Aizpura, ...
bioRxiv, 2023.03. 01.530566, 2023
12023
Changes in iPSC-Astrocyte morphology reflect Alzheimer’s disease patient clinical markers
HA Rowland, G Miller, Q Liu, S Li, NR Sharp, B Ng, T Wei, K Arunasalam, ...
Stem Cells, sxae085, 2024
2024
Exploring multi-omics and clinical characteristics linked to accelerated biological aging in Asian women of reproductive age: insights from the S-PRESTO study
L Chen, KML Tan, J Xu, P Mishra, SA Mir, M Gong, K Narasimhan, B Ng, ...
Genome Medicine 16 (1), 128, 2024
2024
Autophagy Deficits Underly Selective Neuronal Vulnerability to Alpha Synuclein Fibrils in Alzheimer's and Parkinson's iPSC Derived Neurons
AS Abey, B Ng, R Heon-Roberts, BC Carlyle, N Bengoa-Vergniory, ...
Alzheimer's Association International Conference, 2024
2024
Do, QB et al.(2023) Early deficits in an in vitro striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation
Q Do, H Noor, RM Gomez, KML Cramb, B Ng, A Abbey, N Ibarra-Aizpura, ...
2024
Investigating Selective Neuronal Vulnerability in Alzheimer’s and Parkinson’s Disease with Induced Pluripotent Stem Cells and Pre‐formed Fibrils
AS Abey, B Ng, R Heon‐Roberts, BC Carlyle, N Bengoa‐Vergniory, ...
Alzheimer's & Dementia 19, e075756, 2023
2023
iPSC‐derived cortical neurons of sporadic Alzheimer’s disease patients reflect their clinical vulnerability
F Bertherat, B Ng, N Bengoa‐Vergniory, BC Carlyle, R Wade‐Martins
Alzheimer's & Dementia 19, e076847, 2023
2023
Differentiation of human cortical neurons (CNs) from induced pluripotent stem cells (iPSCs)
Q Do, B Ng, R Wade-Martins
2023
iPSC-Astrocyte morphology reflects patient clinical markers
HA Rowland, G Miller, Q Liu, N Sharp, B Ng, T Wei, K Arunasalam, ...
bioRxiv, 2023.07. 15.548687, 2023
2023
Do, QB et al.(2023) Early striatal hyperexcitability in an in vitro human striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation
Q Do, B Ng, RM Gomez, D Beccano-Kelly, N Ibarra-Aizpura, MC Caiazza, ...
2023
Differentiation of human cortical neurons (CNs) from induced pluripotent stem cells (iPSCs) and their coculture with rat astrocytes
Q Do, B Ng, R Wade-Martins
2023
Differentiation of human cortical neurons (CNs) from induced pluripotent stem cells (iPSCs) and their cocu...
Q Do, B Ng, R Wade-Martins
2023
iPSC-derived in vitro striatal circuits to understand GBA-associated Parkinson's disease
Q Do, B Ng, N Bengoa-Vergniory, R Wade-Martins
JOURNAL OF NEUROCHEMISTRY 162, 96-97, 2022
2022
Neurons from individual early Alzheimer’s disease patients reflect their clinical vulnerability
B Ng, HA Rowland, T Wei, K Arunasalam, EM Hayes, I Koychev, ...
bioRxiv, 2021.11. 09.467891, 2021
2021
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