Reversal of phenotypic abnormalities by CRISPR/Cas9-mediated gene correction in Huntington disease patient-derived induced pluripotent stem cells X Xu, Y Tay, B Sim, SI Yoon, Y Huang, J Ooi, KH Utami, A Ziaei, B Ng, ... Stem cell reports 8 (3), 619-633, 2017 | 223 | 2017 |
Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson’s iPSC-dopamine neurons DA Beccano-Kelly, M Cherubini, Y Mousba, KML Cramb, S Giussani, ... Iscience 26 (7), 2023 | 14 | 2023 |
Neurons derived from individual early Alzheimer’s disease patients reflect their clinical vulnerability B Ng, HA Rowland, T Wei, K Arunasalam, EM Hayes, I Koychev, ... Brain Communications 4 (6), fcac267, 2022 | 13 | 2022 |
pS421 huntingtin modulates mitochondrial phenotypes and confers neuroprotection in an HD hiPSC model X Xu, B Ng, B Sim, CI Radulescu, NABM Yusof, WI Goh, S Lin, JSY Lim, ... Cell Death & Disease 11 (9), 809, 2020 | 12 | 2020 |
Tau depletion in human neurons mitigates Aβ-driven toxicity B Ng, J Vowles, F Bertherat, A Abey, P Kilfeather, D Beccano-Kelly, ... Molecular Psychiatry, 1-12, 2024 | 8 | 2024 |
Early deficits in an in vitro striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation QB Do, H Noor, R Marquez-Gomez, KML Cramb, B Ng, A Abbey, ... npj Parkinson's Disease 10 (1), 82, 2024 | 2 | 2024 |
Early striatal hyperexcitability in an in vitro human striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation QB Do, B Ng, RM Gomez, D Beccano-Kelly, N Ibarra-Aizpura, ... bioRxiv, 2023.03. 01.530566, 2023 | 1 | 2023 |
Changes in iPSC-Astrocyte morphology reflect Alzheimer’s disease patient clinical markers HA Rowland, G Miller, Q Liu, S Li, NR Sharp, B Ng, T Wei, K Arunasalam, ... Stem Cells, sxae085, 2024 | | 2024 |
Exploring multi-omics and clinical characteristics linked to accelerated biological aging in Asian women of reproductive age: insights from the S-PRESTO study L Chen, KML Tan, J Xu, P Mishra, SA Mir, M Gong, K Narasimhan, B Ng, ... Genome Medicine 16 (1), 128, 2024 | | 2024 |
Autophagy Deficits Underly Selective Neuronal Vulnerability to Alpha Synuclein Fibrils in Alzheimer's and Parkinson's iPSC Derived Neurons AS Abey, B Ng, R Heon-Roberts, BC Carlyle, N Bengoa-Vergniory, ... Alzheimer's Association International Conference, 2024 | | 2024 |
Do, QB et al.(2023) Early deficits in an in vitro striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation Q Do, H Noor, RM Gomez, KML Cramb, B Ng, A Abbey, N Ibarra-Aizpura, ... | | 2024 |
Investigating Selective Neuronal Vulnerability in Alzheimer’s and Parkinson’s Disease with Induced Pluripotent Stem Cells and Pre‐formed Fibrils AS Abey, B Ng, R Heon‐Roberts, BC Carlyle, N Bengoa‐Vergniory, ... Alzheimer's & Dementia 19, e075756, 2023 | | 2023 |
iPSC‐derived cortical neurons of sporadic Alzheimer’s disease patients reflect their clinical vulnerability F Bertherat, B Ng, N Bengoa‐Vergniory, BC Carlyle, R Wade‐Martins Alzheimer's & Dementia 19, e076847, 2023 | | 2023 |
Differentiation of human cortical neurons (CNs) from induced pluripotent stem cells (iPSCs) Q Do, B Ng, R Wade-Martins | | 2023 |
iPSC-Astrocyte morphology reflects patient clinical markers HA Rowland, G Miller, Q Liu, N Sharp, B Ng, T Wei, K Arunasalam, ... bioRxiv, 2023.07. 15.548687, 2023 | | 2023 |
Do, QB et al.(2023) Early striatal hyperexcitability in an in vitro human striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation Q Do, B Ng, RM Gomez, D Beccano-Kelly, N Ibarra-Aizpura, MC Caiazza, ... | | 2023 |
Differentiation of human cortical neurons (CNs) from induced pluripotent stem cells (iPSCs) and their coculture with rat astrocytes Q Do, B Ng, R Wade-Martins | | 2023 |
Differentiation of human cortical neurons (CNs) from induced pluripotent stem cells (iPSCs) and their cocu... Q Do, B Ng, R Wade-Martins | | 2023 |
iPSC-derived in vitro striatal circuits to understand GBA-associated Parkinson's disease Q Do, B Ng, N Bengoa-Vergniory, R Wade-Martins JOURNAL OF NEUROCHEMISTRY 162, 96-97, 2022 | | 2022 |
Neurons from individual early Alzheimer’s disease patients reflect their clinical vulnerability B Ng, HA Rowland, T Wei, K Arunasalam, EM Hayes, I Koychev, ... bioRxiv, 2021.11. 09.467891, 2021 | | 2021 |