Energy parameters in polypeptides. 10. Improved geometrical parameters and nonbonded interactions for use in the ECEPP/3 algorithm, with application to proline-containing peptides G Nemethy, KD Gibson, KA Palmer, CN Yoon, G Paterlini, A Zagari, ... The Journal of Physical Chemistry 96 (15), 6472-6484, 1992 | 807 | 1992 |
Structure of the C2 domain of human factor VIII at 1.5 Å resolution KP Pratt, BW Shen, K Takeshima, EW Davie, K Fujikawa, BL Stoddard Nature 402 (6760), 439-442, 1999 | 407 | 1999 |
Crystal structure of a 30 kDa C-terminal fragment from the γ chain of human fibrinogen VC Yee, KP Pratt, HCF Côté, I Le Trong, DW Chung, EW Davie, ... Structure 5 (1), 125-138, 1997 | 284 | 1997 |
Life in the shadow of a dominant partner: the FVIII-VWF association and its clinical implications for hemophilia A SW Pipe, RR Montgomery, KP Pratt, PJ Lenting, D Lillicrap Blood, The Journal of the American Society of Hematology 128 (16), 2007-2016, 2016 | 227 | 2016 |
The primary fibrin polymerization pocket: three-dimensional structure of a 30-kDa C-terminal γ chain fragment complexed with the peptide Gly-Pro-Arg-Pro KP Pratt, HCF Cote, DW Chung, RE Stenkamp, EW Davie Proceedings of the National Academy of Sciences 94 (14), 7176-7181, 1997 | 211 | 1997 |
Engineered antigen-specific human regulatory T cells: immunosuppression of FVIII-specific T-and B-cell responses YC Kim, AH Zhang, Y Su, SA Rieder, RJ Rossi, RA Ettinger, KP Pratt, ... Blood, The Journal of the American Society of Hematology 125 (7), 1107-1115, 2015 | 176 | 2015 |
Structure of a factor VIII C2 domain–immunoglobulin G4κ Fab complex: identification of an inhibitory antibody epitope on the surface of factor VIII PC Spiegel Jr, M Jacquemin, JMR Saint-Remy, BL Stoddard, KP Pratt Blood, The Journal of the American Society of Hematology 98 (1), 13-19, 2001 | 172 | 2001 |
Hemophilic factor VIII C1-and C2-domain missense mutations and their modeling to the 1.5-angstrom human C2-domain crystal structure ML Liu, BW Shen, S Nakaya, KP Pratt, K Fujikawa, EW Davie, ... Blood, The Journal of the American Society of Hematology 96 (3), 979-987, 2000 | 145 | 2000 |
γ-Chain dysfibrinogenemias: molecular structure-function relationships of naturally occurring mutations in the γ chain of human fibrinogen HCF Côté, ST Lord, KP Pratt Blood, The Journal of the American Society of Hematology 92 (7), 2195-2212, 1998 | 125 | 1998 |
New insights into binding interfaces of coagulation factors V and VIII and their homologues-lessons from high resolution crystal structures P Fuentes-Prior, K Fujikawa, KP Pratt Current Protein and Peptide Science 3 (3), 313-339, 2002 | 95 | 2002 |
Laboratory monitoring in emicizumab-treated persons with hemophilia A J Müller, I Pekrul, B Pötzsch, B Berning, J Oldenburg, M Spannagl Thrombosis and Haemostasis 119 (09), 1384-1393, 2019 | 91 | 2019 |
T‐cell responses over time in a mild hemophilia A inhibitor subject: epitope identification and transient immunogenicity of the corresponding self‐peptide EA James, WW Kwok, RA Ettinger, AR Thompson, KP Pratt Journal of Thrombosis and Haemostasis 5 (12), 2399-2407, 2007 | 89 | 2007 |
Anti-drug antibodies: emerging approaches to predict, reduce or reverse biotherapeutic immunogenicity KP Pratt Antibodies 7 (2), 19, 2018 | 87 | 2018 |
Lineages of human T-cell clones, including T helper 17/T helper 1 cells, isolated at different stages of anti–factor VIII immune responses RA Ettinger, EA James, WW Kwok, AR Thompson, KP Pratt Blood, The Journal of the American Society of Hematology 114 (7), 1423-1428, 2009 | 79 | 2009 |
A preliminary three-dimensional structure of angiogenin. KA Palmer, HA Scheraga, JF Riordan, BL Vallee Proceedings of the National Academy of Sciences 83 (7), 1965-1969, 1986 | 78 | 1986 |
Standard‐geometry chains fitted to X‐ray derived structures: Validation of the rigid‐geometry approximation. I. Chain closure through a limited search of “loop” conformations KA Palmer, HA Scheraga Journal of computational chemistry 12 (4), 505-526, 1991 | 72 | 1991 |
Endogenous factor VIII synthesis from the intron 22–inverted F8 locus may modulate the immunogenicity of replacement therapy for hemophilia A GS Pandey, C Yanover, LM Miller-Jenkins, S Garfield, SA Cole, JE Curran, ... Nature medicine 19 (10), 1318-1324, 2013 | 66 | 2013 |
Progress toward inducing immunologic tolerance to factor VIII DW Scott, KP Pratt, CH Miao Blood, The Journal of the American Society of Hematology 121 (22), 4449-4456, 2013 | 64 | 2013 |
Immunodominant T-cell epitopes in the factor VIII C2 domain are located within an inhibitory antibody binding site KP Pratt, J Qian, E Ellaban, DK Okita, BM Diethelm-Okita, B Conti-Fine, ... Thrombosis and haemostasis 92 (09), 522-528, 2004 | 64 | 2004 |
ELISA system for detection of immune responses to FVIII: a study of 246 samples and correlation with the Bethesda assay MA Sahud, KP Pratt, O Zhukov, K Qu, AR Thompson Haemophilia 13 (3), 317-322, 2007 | 63 | 2007 |