Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin K Ramadan, R Bruderer, FM Spiga, O Popp, T Baur, M Gotta, HH Meyer Nature 450 (7173), 1258-1262, 2007 | 330 | 2007 |
The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks M Meerang, D Ritz, S Paliwal, Z Garajova, M Bosshard, N Mailand, ... Nature cell biology 13 (11), 1376-1382, 2011 | 318 | 2011 |
Metalloprotease SPRTN/DVC1 orchestrates replication-coupled DNA-protein crosslink repair B Vaz, M Popovic, JA Newman, J Fielden, H Aitkenhead, S Halder, ... Molecular cell 64 (4), 704-719, 2016 | 273 | 2016 |
Targeting BRCA1 and BRCA2 deficiencies with G-quadruplex-interacting compounds J Zimmer, EMC Tacconi, C Folio, S Badie, M Porru, K Klare, M Tumiati, ... Molecular cell 61 (3), 449-460, 2016 | 251 | 2016 |
Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features D Lessel, B Vaz, S Halder, PJ Lockhart, I Marinovic-Terzic, ... Nature genetics 46 (11), 1239-1244, 2014 | 230 | 2014 |
A unified model for the G1/S cell cycle transition S Hume, GL Dianov, K Ramadan Nucleic acids research 48 (22), 12483-12501, 2020 | 166 | 2020 |
Human DNA polymerase λ functionally and physically interacts with proliferating cell nuclear antigen in normal and translesion DNA synthesis G Maga, G Villani, K Ramadan, I Shevelev, NT Le Gac, L Blanco, ... Journal of Biological Chemistry 277 (50), 48434-48440, 2002 | 142 | 2002 |
Chromatin retention of DNA damage sensors DDB2 and XPC through loss of p97 segregase causes genotoxicity MR Puumalainen, D Lessel, P Rüthemann, N Kaczmarek, K Bachmann, ... Nature communications 5 (1), 3695, 2014 | 137 | 2014 |
De novo DNA synthesis by human DNA polymerase λ, DNA polymerase μ and terminal deoxyribonucleotidyl transferase K Ramadan, IV Shevelev, G Maga, U Hübscher Journal of molecular biology 339 (2), 395-404, 2004 | 120 | 2004 |
The DNA-polymerase-X family: controllers of DNA quality? K Ramadan, I Shevelev, U Hübscher Nature Reviews Molecular Cell Biology 5 (12), 1038-1043, 2004 | 119 | 2004 |
Role of p97/VCP (Cdc48) in genome stability B Vaz, S Halder, K Ramadan Frontiers in genetics 4, 60, 2013 | 114 | 2013 |
The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin DB Krastev, S Li, Y Sun, AJ Wicks, G Hoslett, D Weekes, LM Badder, ... Nature cell biology 24 (1), 62-73, 2022 | 108 | 2022 |
Human DNA polymerase λ possesses terminal deoxyribonucleotidyl transferase activity and can elongate RNA primers: implications for novel functions K Ramadan, G Maga, IV Shevelev, G Villani, L Blanco, U Hübscher Journal of molecular biology 328 (1), 63-72, 2003 | 107 | 2003 |
DNA–protein crosslink proteolysis repair B Vaz, M Popovic, K Ramadan Trends in biochemical sciences 42 (6), 483-495, 2017 | 104 | 2017 |
TEX264 coordinates p97-and SPRTN-mediated resolution of topoisomerase 1-DNA adducts J Fielden, K Wiseman, I Torrecilla, S Li, S Hume, SC Chiang, A Ruggiano, ... Nature communications 11 (1), 1274, 2020 | 96 | 2020 |
DNA polymerase λ from calf thymus preferentially replicates damaged DNA K Ramadan, IV Shevelev, G Maga, U Hübscher Journal of Biological Chemistry 277 (21), 18454-18458, 2002 | 93 | 2002 |
Human DNA Polymerase λ Diverged in Evolution from DNA Polymerase β toward Specific Mn++ Dependence: a Kinetic and Thermodynamic Study G Blanca, I Shevelev, K Ramadan, G Villani, S Spadari, U Hübscher, ... Biochemistry 42 (24), 7467-7476, 2003 | 90 | 2003 |
Human DNA polymerases λ and β show different efficiencies of translesion DNA synthesis past abasic sites and alternative mechanisms for frameshift generation G Blanca, G Villani, I Shevelev, K Ramadan, S Spadari, U Hübscher, ... Biochemistry 43 (36), 11605-11615, 2004 | 85 | 2004 |
DNA–protein crosslink proteases in genome stability A Ruggiano, K Ramadan Communications Biology 4 (1), 11, 2021 | 79 | 2021 |
DNA protein crosslink proteolysis repair: From yeast to premature ageing and cancer in humans J Fielden, A Ruggiano, M Popović, K Ramadan DNA repair 71, 198-204, 2018 | 79 | 2018 |