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Hao-Jie Zhu
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引用次数
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年份
The effects of Milk Thistle (Silybum marianum) on human cytochrome P450 activity
M Kawaguchi-Suzuki, RF Frye, HJ Zhu, BJ Brinda, KD Chavin, ...
Drug Metabolism and Disposition 42 (10), 1611-1616, 2014
4372014
Characterization of P-glycoprotein inhibition by major cannabinoids from marijuana
HJ Zhu, JS Wang, JS Markowitz, JL Donovan, BB Gibson, HA Gefroh, ...
Journal of Pharmacology and Experimental Therapeutics 317 (2), 850-857, 2006
2562006
Two CES1 gene mutations lead to dysfunctional carboxylesterase 1 activity in man: clinical significance and molecular basis
HJ Zhu, KS Patrick, HJ Yuan, JS Wang, JL Donovan, CL DeVane, ...
The American Journal of Human Genetics 82 (6), 1241-1248, 2008
2452008
Carboxylesterase 1 as a determinant of clopidogrel metabolism and activation
HJ Zhu, X Wang, BE Gawronski, BJ Brinda, DJ Angiolillo, JS Markowitz
Journal of Pharmacology and Experimental Therapeutics 344 (3), 665-672, 2013
1832013
Glutamate up-regulates P-glycoprotein expression in rat brain microvessel endothelial cells by an NMDA receptor-mediated mechanism
HJ Zhu, GQ Liu
Life sciences 75 (11), 1313-1322, 2004
1462004
Evaluation of antipsychotic drugs as inhibitors of multidrug resistance transporter P-glycoprotein
JS Wang, HJ Zhu, JS Markowitz, JL Donovan, CL DeVane
Psychopharmacology 187 (4), 415-423, 2006
1452006
Berberine promotes glucagon-like peptide-1 (7–36) amide secretion in streptozotocin-induced diabetic rats
SS Lu, YL Yu, HJ Zhu, XD Liu, L Liu, YW Liu, P Wang, L Xie, GJ Wang
Journal of Endocrinology 200 (2), 159-165, 2009
1422009
Age-and sex-related expression and activity of carboxylesterase 1 and 2 in mouse and human liver
HJ Zhu, DI Appel, Y Jiang, JS Markowitz
Drug Metabolism and Disposition 37 (9), 1819-1825, 2009
982009
Risperidone and paliperidone inhibit p-glycoprotein activity in vitro
HJ Zhu, JS Wang, JS Markowitz, JL Donovan, BB Gibson, CL DeVane
Neuropsychopharmacology 32 (4), 757-764, 2007
962007
Activation of the antiviral prodrug oseltamivir is impaired by two newly identified carboxylesterase 1 variants
HJ Zhu, JS Markowitz
Drug Metabolism and Disposition 37 (2), 264-267, 2009
922009
Dabigatran etexilate activation is affected by the CES1 genetic polymorphism G143E (rs71647871) and gender
J Shi, X Wang, JH Nguyen, BE Bleske, Y Liang, L Liu, HJ Zhu
Biochemical Pharmacology 119, 76-84, 2016
902016
An assessment of pharmacokinetics and antioxidant activity of free silymarin flavonolignans in healthy volunteers: A dose escalation study
HJ Zhu, BJ Brinda, KD Chavin, HJ Bernstein, KS Patrick, JS Markowitz
Drug Metabolism and Disposition 41 (9), 1679-1685, 2013
882013
Sertraline and its metabolite desmethylsertraline, but not bupropion or its three major metabolites, have high affinity for P-glycoprotein
JS Wang, HJ Zhu, BB Gibson, JS Markowitz, JL Donovan, CL DeVane
Biological & pharmaceutical bulletin 31 (2), 231, 2008
862008
Long-term consequences of methamphetamine exposure in young adults are exacerbated in glial cell line-derived neurotrophic factor heterozygous mice
HA Boger, LD Middaugh, KS Patrick, S Ramamoorthy, ED Denehy, H Zhu, ...
The Journal of Neuroscience 27 (33), 8816-8825, 2007
822007
Pharmacokinetics of Olanzapine After Single‐Dose Oral Administration of Standard Tablet Versus Normal and Sublingual Administration of an Orally Disintegrating Tablet in Normal …
JS Markowitz, CL DeVane, RJ Malcolm, HA Gefroh, JS Wang, HJ Zhu, ...
The Journal of Clinical Pharmacology 46 (2), 164-171, 2006
802006
Role of carboxylesterase 1 and impact of natural genetic variants on the hydrolysis of trandolapril
HJ Zhu, DI Appel, JA Johnson, KD Chavin, JS Markowitz
Biochemical pharmacology 77 (7), 1266-1272, 2009
732009
Antipsychotic drugs inhibit the function of breast cancer resistance protein
JS Wang, HJ Zhu, JS Markowitz, JL Donovan, HJ Yuan, CL DeVane
Basic & clinical pharmacology & toxicology 103 (4), 336-341, 2008
672008
Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation
J Shi, X Wang, J Nguyen, AH Wu, BE Bleske, HJ Zhu
Drug Metab Dispos, 2016
642016
Population pharmacokinetic analysis of drug–drug interactions among risperidone, bupropion, and sertraline in CF1 mice
JS Wang, CL DeVane, BB Gibson, JL Donovan, JS Markowitz, HJ Zhu
Psychopharmacology 183 (4), 490-499, 2006
622006
Evaluation of organic cation transporter 3 (SLC22A3) inhibition as a potential mechanism of antidepressant action
HJ Zhu, DI Appel, D Gründemann, E Richelson, JS Markowitz
Pharmacological Research 65 (4), 491-496, 2012
612012
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