Structures of human Patched and its complex with native palmitoylated sonic hedgehog X Qi, P Schmiege, E Coutavas, J Wang, X Li Nature 560 (7716), 128-132, 2018 | 172 | 2018 |
Cryo-EM structure of oxysterol-bound human Smoothened coupled to a heterotrimeric Gi X Qi, H Liu, B Thompson, J McDonald, C Zhang, X Li Nature 571 (7764), 279-283, 2019 | 148 | 2019 |
A LysM receptor heteromer mediates perception of arbuscular mycorrhizal symbiotic signal in rice J He, C Zhang, H Dai, H Liu, X Zhang, J Yang, X Chen, Y Zhu, D Wang, ... Molecular Plant 12 (12), 1561-1576, 2019 | 129 | 2019 |
Two Patched molecules engage distinct sites on Hedgehog yielding a signaling-competent complex X Qi, P Schmiege, E Coutavas, X Li Science 362 (6410), eaas8843, 2018 | 122 | 2018 |
Mechanistic insights into the generation and transduction of hedgehog signaling X Qi, X Li Trends in biochemical sciences 45 (5), 397-410, 2020 | 68 | 2020 |
Structural basis for itraconazole-mediated NPC1 inhibition T Long, X Qi, A Hassan, Q Liang, JK De Brabander, X Li Nature communications 11 (1), 152, 2020 | 68 | 2020 |
Sterols in an intramolecular channel of Smoothened mediate Hedgehog signaling X Qi, L Friedberg, R De Bose-Boyd, T Long, X Li Nature chemical biology 16 (12), 1368-1375, 2020 | 67 | 2020 |
Structure of nevanimibe-bound tetrameric human ACAT1 T Long, Y Sun, A Hassan, X Qi, X Li Nature 581 (7808), 339-343, 2020 | 66 | 2020 |
Structural basis of intramitochondrial phosphatidic acid transport mediated by U ps1‐M dm35 complex F Yu, F He, H Yao, C Wang, J Wang, J Li, X Qi, H Xue, J Ding, P Zhang EMBO reports 16 (7), 813-823, 2015 | 57 | 2015 |
Molecular basis of cholesterol efflux via ABCG subfamily transporters Y Sun, J Wang, T Long, X Qi, L Donnelly, N Elghobashi-Meinhardt, ... Proceedings of the National Academy of Sciences 118 (34), e2110483118, 2021 | 56 | 2021 |
Structure and mechanism of a group-I cobalt energy coupling factor transporter Z Bao, X Qi, S Hong, K Xu, F He, M Zhang, J Chen, D Chao, W Zhao, D Li, ... Cell research 27 (5), 675-687, 2017 | 48 | 2017 |
Mechanisms and inhibition of Porcupine-mediated Wnt acylation Y Liu, X Qi, L Donnelly, N Elghobashi-Meinhardt, T Long, RW Zhou, ... Nature 607 (7920), 816-822, 2022 | 47 | 2022 |
Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain H Chen, X Qi, RA Faulkner, MM Schumacher, LM Donnelly, ... Nature communications 13 (1), 4273, 2022 | 27 | 2022 |
Structural basis of rifampin inactivation by rifampin phosphotransferase X Qi, W Lin, M Ma, C Wang, Y He, N He, J Gao, H Zhou, Y Xiao, Y Wang, ... Proceedings of the National Academy of Sciences 113 (14), 3803-3808, 2016 | 25 | 2016 |
Marked structural rearrangement of mannose 6-phosphate/IGF2 receptor at different pH environments R Wang, X Qi, P Schmiege, E Coutavas, X Li Science Advances 6 (7), eaaz1466, 2020 | 22 | 2020 |
Molecular basis of Wnt biogenesis, secretion, and Wnt7-specific signaling X Qi, Q Hu, N Elghobashi-Meinhardt, T Long, H Chen, X Li Cell 186 (23), 5028-5040. e14, 2023 | 4 | 2023 |
Expression, Purification, and Structure Determination of Human PTCH1–HH-N Complexes X Qi, P Schmiege, L Esparza, X Li Hedgehog Signaling: Methods and Protocols, 107-120, 2022 | 2 | 2022 |