Platensimycin is a selective FabF inhibitor with potent antibiotic properties J Wang, SM Soisson, K Young, W Shoop, S Kodali, A Galgoci, R Painter, ... Nature 441 (7091), 358-361, 2006 | 1011 | 2006 |
Towards the sustainable discovery and development of new antibiotics M Miethke, M Pieroni, T Weber, M Brönstrup, P Hammann, L Halby, ... Nature Reviews Chemistry 5 (10), 726-749, 2021 | 622 | 2021 |
New PCR primers for the screening of NRPS and PKS-I systems in actinomycetes: detection and distribution of these biosynthetic gene sequences in major taxonomic groups A Ayuso-Sacido, O Genilloud Microbial ecology 49 (1), 10-24, 2005 | 510 | 2005 |
New developments in RiPP discovery, enzymology and engineering M Montalbán-López, TA Scott, S Ramesh, IR Rahman, AJ Van Heel, ... Natural product reports 38 (1), 130-239, 2021 | 504 | 2021 |
Actinomycetes: still a source of novel antibiotics O Genilloud Natural product reports 34 (10), 1203-1232, 2017 | 457 | 2017 |
Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties J Wang, S Kodali, SH Lee, A Galgoci, R Painter, K Dorso, F Racine, ... Proceedings of the National Academy of Sciences 104 (18), 7612-7616, 2007 | 452 | 2007 |
Isolation, structure, and absolute stereochemistry of platensimycin, a broad spectrum antibiotic discovered using an antisense differential sensitivity strategy SB Singh, H Jayasuriya, JG Ondeyka, KB Herath, C Zhang, DL Zink, ... Journal of the American Chemical Society 128 (36), 11916-11920, 2006 | 299 | 2006 |
Current approaches to exploit actinomycetes as a source of novel natural products O Genilloud, I González, O Salazar, J Martín, JR Tormo, F Vicente Journal of Industrial Microbiology and Biotechnology 38 (3), 375-389, 2011 | 276 | 2011 |
Patterns of antimicrobial activities from soil actinomycetes isolated under different conditions of pH and salinity A Basilio, I Gonzalez, MF Vicente, J Gorrochategui, A Cabello, ... Journal of applied microbiology 95 (4), 814-823, 2003 | 273 | 2003 |
Isolation and structure of platencin: a FabH and FabF dual inhibitor with potent broad‐spectrum antibiotic activity H Jayasuriya, KB Herath, C Zhang, DL Zink, A Basilio, O Genilloud, ... Angewandte Chemie International Edition 46 (25), 4684-4688, 2007 | 246 | 2007 |
Actinomycetes isolated from lichens: evaluation of their diversity and detection of biosynthetic gene sequences I González, A Ayuso-Sacido, A Anderson, O Genilloud FEMS microbiology ecology 54 (3), 401-415, 2005 | 231 | 2005 |
Discovery of kibdelomycin, a potent new class of bacterial type II topoisomerase inhibitor by chemical-genetic profiling in Staphylococcus aureus JW Phillips, MA Goetz, SK Smith, DL Zink, J Polishook, R Onishi, ... Chemistry & biology 18 (8), 955-965, 2011 | 182 | 2011 |
A New Approach to Drug Discovery: High-Throughput Screening of Microbial Natural Extracts against Aspergillus fumigatus Using Resazurin MC Monteiro, M de la Cruz, J Cantizani, C Moreno, JR Tormo, E Mellado, ... Journal of biomolecular screening 17 (4), 542-549, 2012 | 176 | 2012 |
Evolution, taxonomy and ecology of the genus Thelebolus in Antarctica GS De Hoog, E Gottlich, G Platas, O Genilloud, G Leotta, ... Studies in Mycology 51, 33, 2004 | 165 | 2004 |
The re-emerging role of microbial natural products in antibiotic discovery O Genilloud Antonie Van Leeuwenhoek 106, 173-188, 2014 | 146 | 2014 |
Sponge-derived Kocuria and Micrococcus spp. as sources of the new thiazolyl peptide antibiotic kocurin S Palomo, I González, M De la Cruz, J Martín, JR Tormo, M Anderson, ... Marine drugs 11 (4), 1071-1086, 2013 | 132 | 2013 |
The complestatins as HIV-1 integrase inhibitors. Efficient isolation, structure elucidation, and inhibitory activities of isocomplestatin, chloropeptin I, new complestatins, A … SB Singh, H Jayasuriya, GM Salituro, DL Zink, A Shafiee, B Heimbuch, ... Journal of Natural Products 64 (7), 874-882, 2001 | 124 | 2001 |
Defensive mutualism in microbial symbiosis JF White Jr, MS Torres CRC Press, 2009 | 120 | 2009 |
New Ikarugamycin Derivatives with Antifungal and Antibacterial Properties from Streptomyces zhaozhouensis R Lacret, D Oves-Costales, C Gómez, C Díaz, M De la Cruz, ... Marine drugs 13 (1), 128-140, 2014 | 103 | 2014 |
The transposon Tn5 carries a bleomycin-resistance determinant O Genilloud, MC Garrido, F Moreno Gene 32 (1-2), 225-233, 1984 | 101 | 1984 |