Novel cyano-and amidino-substituted derivatives of thieno [2, 3-b]-and thieno [3, 2-b] thiophene-2-carboxanilides and thieno [3′, 2′: 4, 5] thieno-and thieno [2′, 3′: 4, 5 … I Jarak, M Kralj, I Piantanida, L Šuman, M Žinić, K Pavelić, ... Bioorganic & medicinal chemistry 14 (8), 2859-2868, 2006 | 98 | 2006 |
Metabolomics of silver nanoparticles toxicity in HaCaT cells: structure–activity relationships and role of ionic silver and oxidative stress J Carrola, V Bastos, I Jarak, R Oliveira-Silva, E Malheiro, ... Nanotoxicology 10 (8), 1105-1117, 2016 | 96 | 2016 |
Novel Cyano- and N-Isopropylamidino-Substituted Derivatives of Benzo[b]thiophene-2-carboxanilides and Benzo[b]thieno[2,3-c]quinolones: Synthesis … I Jarak, M Kralj, L Šuman, G Pavlović, J Dogan, I Piantanida, M Žinić, ... Journal of medicinal chemistry 48 (7), 2346-2360, 2005 | 94 | 2005 |
Where is nano today and where is it headed? A review of nanomedicine and the dilemma of nanotoxicology C Domingues, A Santos, C Alvarez-Lorenzo, A Concheiro, I Jarak, ... ACS nano 16 (7), 9994-10041, 2022 | 81 | 2022 |
Glucose uptake and lipid metabolism are impaired in epicardial adipose tissue from heart failure patients with or without diabetes A Burgeiro, A Fuhrmann, S Cherian, D Espinoza, I Jarak, RA Carvalho, ... American journal of physiology-endocrinology and metabolism 310 (7), E550-E564, 2016 | 65 | 2016 |
Novel substituted benzothiophene and thienothiophene carboxanilides and quinolones: synthesis, photochemical synthesis, DNA-binding properties, antitumor evaluation and 3D … M Aleksic, B Bertosa, R Nhili, L Uzelac, I Jarak, S Depauw, ... Journal of medicinal chemistry 55 (11), 5044-5060, 2012 | 59 | 2012 |
Pluronic-based nanovehicles: Recent advances in anticancer therapeutic applications I Jarak, CL Varela, ET da Silva, FFM Roleira, F Veiga, A Figueiras European Journal of Medicinal Chemistry 206, 112526, 2020 | 58 | 2020 |
Micelleplexes as nucleic acid delivery systems for cancer-targeted therapies M Pereira-Silva, I Jarak, C Alvarez-Lorenzo, A Concheiro, AC Santos, ... Journal of Controlled Release 323, 442-462, 2020 | 55 | 2020 |
Senescence and declining reproductive potential: Insight into molecular mechanisms through testicular metabolomics I Jarak, S Almeida, RA Carvalho, M Sousa, A Barros, MG Alves, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (10 …, 2018 | 47 | 2018 |
A switch from high-fat to normal diet does not restore sperm quality but prevents metabolic syndrome L Crisóstomo, L Rato, I Jarak, BM Silva, JF Raposo, RL Batterham, ... Reproduction 158 (4), 377-387, 2019 | 46 | 2019 |
Effects of dietary carbohydrate on hepatic de novo lipogenesis in European seabass (Dicentrarchus labrax L.) I Viegas, I Jarak, J Rito, RA Carvalho, I Metón, MA Pardal, IV Baanante, ... Journal of lipid research 57 (7), 1264-1272, 2016 | 46 | 2016 |
From the cover: metabolism modulation in different organs by silver nanoparticles: an NMR metabolomics study of a mouse model I Jarak, J Carrola, AS Barros, AM Gil, ML Pereira, ML Corvo, IF Duarte Toxicological Sciences 159 (2), 422-435, 2017 | 45 | 2017 |
MAPK/ERK pathway inhibition is a promising treatment target for adrenocortical tumors SS Pereira, MP Monteiro, MM Costa, J Ferreira, MG Alves, PF Oliveira, ... Journal of cellular biochemistry 120 (1), 894-906, 2019 | 41 | 2019 |
Analysis of glucose metabolism in farmed European sea bass (Dicentrarchus labrax L.) using deuterated water I Viegas, VM Mendes, S Leston, I Jarak, RA Carvalho, MÂ Pardal, ... Comparative Biochemistry and Physiology Part A: Molecular & Integrative …, 2011 | 39 | 2011 |
Novel pentamidine derivatives: Synthesis, anti-tumor properties and polynucleotide-binding activities I Jarak, M Marjanović, I Piantanida, M Kralj, G Karminski-Zamola European journal of medicinal chemistry 46 (7), 2807-2815, 2011 | 39 | 2011 |
Novel Derivatives of Pyridylbenzo[b]thiophene-2-carboxamides and Benzo[b]thieno[2,3-c]naphthyridin-2-ones: Minor Structural Variations Provoke Major … K Ester, M Hranjec, I Piantanida, I Caleta, I Jarak, K Pavelić, M Kralj, ... Journal of medicinal chemistry 52 (8), 2482-2492, 2009 | 39 | 2009 |
High sucrose consumption induces memory impairment in rats associated with electrophysiological modifications but not with metabolic changes in the hippocampus C Lemos, D Rial, FQ Gonçalves, J Pires, HB Silva, FC Matheus, ... Neuroscience 315, 196-205, 2016 | 38 | 2016 |
Diet during early life defines testicular lipid content and sperm quality in adulthood L Crisóstomo, RA Videira, I Jarak, K Starčević, T Mašek, L Rato, ... American Journal of Physiology-Endocrinology and Metabolism 319 (6), E1061-E1073, 2020 | 35 | 2020 |
Effects of food-deprivation and refeeding on the regulation and sources of blood glucose appearance in European seabass (Dicentrarchus labrax L.) I Viegas, J Rito, JD González, I Jarak, RA Carvalho, I Metón, MA Pardal, ... Comparative Biochemistry and Physiology Part A: Molecular & Integrative …, 2013 | 35 | 2013 |
IGF2 role in adrenocortical carcinoma biology SS Pereira, MP Monteiro, MM Costa, Â Moreira, MG Alves, PF Oliveira, ... Endocrine 66, 326-337, 2019 | 32 | 2019 |