| Taxol: Mechanisms of Action and Resistance a SB Horwitz, L Lothstein, JJ Manfredi, W Mellado, J Parness, SN Roy, ... Annals of the New York Academy of Sciences 466 (1), 733-744, 1986 | 281 | 1986 |
| Differential overexpression of three mdr gene family members in multidrug-resistant J774. 2 mouse cells. Evidence that distinct P-glycoprotein precursors are encoded by unique … SI Hsu, L Lothstein, SB Horwitz Journal of Biological Chemistry 264 (20), 12053-12062, 1989 | 277 | 1989 |
| ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-κB through a common MEK/extracellular signal-regulated kinase/p90rsk signaling pathway in response to … GR Panta, S Kaur, LG Cavin, ML Cortés, F Mercurio, L Lothstein, ... Molecular and Cellular Biology 24 (5), 1823-1835, 2004 | 169 | 2004 |
| Structural analysis of the mouse mdr1a (P-glycoprotein) promoter reveals the basis for differential transcript heterogeneity in multidrug-resistant J774. 2 cells. SI Hsu, D Cohen, LS Kirschner, L Lothstein, M Hartstein, SB Horwitz Molecular and Cellular Biology 10 (7), 3596-3606, 1990 | 157 | 1990 |
| Distinct P-glycoprotein precursors are overproduced in independently isolated drug-resistant cell lines LM Greenberger, L Lothstein, SS Williams, SB Horwitz Proceedings of the National Academy of Sciences 85 (11), 3762-3766, 1988 | 126 | 1988 |
| General organization of protein in HeLa 40S nuclear ribonucleoprotein particles. L Lothstein, HP Arenstorf, SY Chung, BW Walker, JC Wooley, ... The Journal of cell biology 100 (5), 1570-1581, 1985 | 103 | 1985 |
| Circumvention of P-GP MDR as a function of anthracycline lipophilicity and charge TJ Lampidis, D Kolonias, T Podona, M Israel, AR Safa, L Lothstein, ... Biochemistry 36 (9), 2679-2685, 1997 | 98 | 1997 |
| Anthracycline drug targeting: cytoplasmic versus nuclear–a fork in the road L Lothstein, M Israel, TW Sweatman Drug Resistance Updates 4 (3), 169-177, 2001 | 91 | 2001 |
| The composition and general topology of RNA and protein in monomer 40 S ribonucleoprotein particles WM LeStourgeon, L Lothstein, BW Walker, AL Beyer Nuclear Particles: The Cell Nucleus, Vol. 9 9, 49, 2013 | 61* | 2013 |
| THE COMPOSITION AND GENERAL TOPOLOGY OF RNA AND PROTEIN IN MONOMER 40S RIBONUCLEOPROTEIN-PARTICLES WM LESTOURGEON, L LOTHSTEIN, BW WALKER, AL BEYER BIOLOGIE CELLULAIRE 39 (3), A51-A51, 1980 | 61 | 1980 |
| Phosphorylation of mitochondrial phospholipid scramblase 3 by protein kinase C‐δ induces its activation and facilitates mitochondrial targeting of tBid Y He, J Liu, D Grossman, D Durrant, T Sweatman, L Lothstein, RF Epand, ... Journal of cellular biochemistry 101 (5), 1210-1221, 2007 | 60 | 2007 |
| The release of 40S hnRNP particles by brief digestion of HeLa nuclei with micrococcal nuclease BW Walker, L Lothstein, CL Baker, WM LeStourgeon Nucleic acids research 8 (16), 3639-3658, 1980 | 51 | 1980 |
| The structure of chromatin containing DNA complementary to 19 S and 26 S ribosomal RNA in active and inactive stages of Physarum polycephalum EM Johnson, HR Matthews, VC Littau, L Lothstein, EM Bradbury, ... Archives of biochemistry and biophysics 191 (2), 537-550, 1978 | 50 | 1978 |
| Alternate overexpression of two P-glycoprotein [corrected] genes is associated with changes in multidrug resistance in a J774. 2 cell line. L Lothstein, SI Hsu, SB Horwitz, LM Greenberger Journal of Biological Chemistry 264 (27), 16054-16058, 1989 | 48 | 1989 |
| Interferon-resistant Daudi cell line with a Stat2 defect is resistant to apoptosis induced by chemotherapeutic agents Z Du, M Fan, JG Kim, D Eckerle, L Lothstein, L Wei, LM Pfeffer Journal of Biological Chemistry 284 (41), 27808-27815, 2009 | 35 | 2009 |
| Involvement of PKC delta (PKCδ) in the resistance against different doxorubicin analogs MID Bessone, DE Berardi, PB Campodónico, LB Todaro, L Lothstein, ... Breast cancer research and treatment 126 (3), 577-587, 2011 | 33 | 2011 |
| Novel Extranuclear-targeted Anthracyclines Override the Antiapoptotic Functions of Bcl-2 and Target Protein Kinase C Pathways to Induce Apoptosis 1 Supported in part by grants … CM Barrett, FL Lewis, JB Roaten, TW Sweatman, M Israel, JL Cleveland, ... Molecular cancer therapeutics 1 (7), 469-481, 2002 | 33 | 2002 |
| Protection from doxorubicin-induced cardiomyopathy using the modified anthracycline N-benzyladriamycin-14-valerate (AD 198) C Cai, L Lothstein, RR Morrison, PA Hofmann Journal of Pharmacology and Experimental Therapeutics 335 (1), 223-230, 2010 | 31 | 2010 |
| Expression of phenotypic traits following modulation of colchicine resistance in J774. 2 cells L Lothstein, SB Horwitz Journal of cellular physiology 127 (2), 253-260, 1986 | 31 | 1986 |
| N-Benzyladriamycin-14-Valerate (AD198) Induces Apoptosis through Protein Kinase C-δ–Induced Phosphorylation of Phospholipid Scramblase 3 Y He, J Liu, D Durrant, HS Yang, T Sweatman, L Lothstein, RM Lee Cancer research 65 (21), 10016-10023, 2005 | 30 | 2005 |
