| Targeted rescue of a destabilized mutant of p53 by an in silico screened drug FM Boeckler, AC Joerger, G Jaggi, TJ Rutherford, DB Veprintsev, ... Proceedings of the National Academy of Sciences 105 (30), 10360-10365, 2008 | 439 | 2008 |
| Universal allosteric mechanism for Gα activation by GPCRs T Flock, CNJ Ravarani, D Sun, AJ Venkatakrishnan, M Kayikci, CG Tate, ... Nature 524 (7564), 173-179, 2015 | 383 | 2015 |
| Structures of SAS-6 suggest its organization in centrioles M van Breugel, M Hirono, A Andreeva, H Yanagisawa, S Yamaguchi, ... Science 331 (6021), 1196-1199, 2011 | 373 | 2011 |
| A peptide that binds and stabilizes p53 core domain: chaperone strategy for rescue of oncogenic mutants A Friedler, LO Hansson, DB Veprintsev, SMV Freund, TM Rippin, ... Proceedings of the National Academy of Sciences 99 (2), 937-942, 2002 | 347 | 2002 |
| Hsp90-Tau complex reveals molecular basis for specificity in chaperone action GE Karagöz, AMS Duarte, E Akoury, H Ippel, J Biernat, TM Luengo, ... Cell 156 (5), 963-974, 2014 | 336 | 2014 |
| Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region AJ Venkatakrishnan, X Deupi, G Lebon, FM Heydenreich, T Flock, ... Nature 536 (7617), 484-487, 2016 | 329 | 2016 |
| Cooperative binding of tetrameric p53 to DNA RL Weinberg, DB Veprintsev, AR Fersht Journal of molecular biology 341 (5), 1145-1159, 2004 | 316 | 2004 |
| ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes H Teo, DJ Gill, J Sun, O Perisic, DB Veprintsev, Y Vallis, SD Emr, ... Cell 125 (1), 99-111, 2006 | 312 | 2006 |
| Comparative binding of p53 to its promoter and DNA recognition elements RL Weinberg, DB Veprintsev, M Bycroft, AR Fersht Journal of molecular biology 348 (3), 589-596, 2005 | 246 | 2005 |
| Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium Z Hayouka, J Rosenbluh, A Levin, S Loya, M Lebendiker, D Veprintsev, ... Proceedings of the National Academy of Sciences 104 (20), 8316-8321, 2007 | 233 | 2007 |
| Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor MR Fernandez-Fernandez, DB Veprintsev, AR Fersht Proceedings of the National Academy of Sciences 102 (13), 4735-4740, 2005 | 232 | 2005 |
| The DNA-binding domain of human PARP-1 interacts with DNA single-strand breaks as a monomer through its second zinc finger S Eustermann, H Videler, JC Yang, PT Cole, D Gruszka, D Veprintsev, ... Journal of molecular biology 407 (1), 149-170, 2011 | 211 | 2011 |
| Backbone NMR reveals allosteric signal transduction networks in the β1-adrenergic receptor S Isogai, X Deupi, C Opitz, FM Heydenreich, CJ Tsai, F Brueckner, ... Nature 530 (7589), 237-241, 2016 | 198 | 2016 |
| Structures of p53 cancer mutants and mechanism of rescue by second-site suppressor mutations AC Joerger, HC Ang, DB Veprintsev, CM Blair, AR Fersht Journal of Biological Chemistry 280 (16), 16030-16037, 2005 | 198 | 2005 |
| Structural insight into the ESCRT‐I/‐II link and its role in MVB trafficking DJ Gill, H Teo, J Sun, O Perisic, DB Veprintsev, SD Emr, RL Williams The EMBO journal 26 (2), 600-612, 2007 | 185 | 2007 |
| The central region of HDM2 provides a second binding site for p53 GW Yu, S Rudiger, D Veprintsev, S Freund, MR Fernandez-Fernandez, ... Proceedings of the National Academy of Sciences 103 (5), 1227-1232, 2006 | 171 | 2006 |
| Kinetic instability of p53 core domain mutants: implications for rescue by small molecules A Friedler, DB Veprintsev, LO Hansson, AR Fersht Journal of Biological Chemistry 278 (26), 24108-24112, 2003 | 170 | 2003 |
| Structural evolution of p53, p63, and p73: implication for heterotetramer formation AC Joerger, S Rajagopalan, E Natan, DB Veprintsev, CV Robinson, ... Proceedings of the National Academy of Sciences 106 (42), 17705-17710, 2009 | 167 | 2009 |
| Structure and disassembly of filaments formed by the ESCRT-III subunit Vps24 S Ghazi-Tabatabai, S Saksena, JM Short, AV Pobbati, DB Veprintsev, ... Structure 16 (9), 1345-1356, 2008 | 167 | 2008 |
| Structural basis for Arl1-dependent targeting of homodimeric GRIP domains to the Golgi apparatus B Panic, O Perisic, DB Veprintsev, RL Williams, S Munro Molecular cell 12 (4), 863-874, 2003 | 156 | 2003 |
Alan FershtEmeritus Group Leader, MRC Laboratory of Molecular Biology, University of Cambridge在 cam.ac.uk 的电子邮件经过验证
