Prodrugs for amines AL Simplício, JM Clancy, JF Gilmer Molecules 13 (3), 519-547, 2008 | 219 | 2008 |
Matrix metalloproteinases in inflammatory bowel disease: an update S O’Sullivan, JF Gilmer, C Medina Mediators of inflammation 2015 (1), 964131, 2015 | 204 | 2015 |
Inhibition of acetylcholinesterase by tea tree oil C Mills, BV Cleary, JJ Walsh, JF Gilmer Journal of Pharmacy and Pharmacology 56 (3), 375-379, 2004 | 195 | 2004 |
Nitric oxide-matrix metaloproteinase-9 interactions: biological and pharmacological significance: NO and MMP-9 interactions S O'Sullivan, C Medina, M Ledwidge, MW Radomski, JF Gilmer Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1843 (3), 603-617, 2014 | 121 | 2014 |
A steroid‐based cryptand for halide anions AP Davis, JF Gilmer, JJ Perry Angewandte Chemie International Edition in English 35 (12), 1312-1315, 1996 | 116 | 1996 |
Mechanisms of platelet-stimulated colon cancer invasion: role of clusterin and thrombospondin 1 in regulation of the P38MAPK–MMP-9 pathway A Radziwon-Balicka, MJ Santos-Martinez, JJ Corbalan, S O’Sullivan, ... Carcinogenesis 35 (2), 324-332, 2014 | 103 | 2014 |
Bile acid toxicity structure–activity relationships: correlations between cell viability and lipophilicity in a panel of new and known bile acids using an oesophageal cell line … R Sharma, F Majer, VK Peta, J Wang, R Keaveney, D Kelleher, A Long, ... Bioorganic & medicinal chemistry 18 (18), 6886-6895, 2010 | 78 | 2010 |
Advances in bile acid medicinal chemistry R Sharma, A Long, JF Gilmer Current medicinal chemistry 18 (26), 4029-4052, 2011 | 74 | 2011 |
Isosorbide-2-benzyl carbamate-5-salicylate, a peripheral anionic site binding subnanomolar selective butyrylcholinesterase inhibitor CG Carolan, GP Dillon, D Khan, SA Ryder, JM Gaynor, S Reidy, ... Journal of medicinal chemistry 53 (3), 1190-1199, 2010 | 71 | 2010 |
β-Aminoketones as prodrugs with pH-controlled activation AL Simplício, JM Clancy, JF Gilmer International journal of pharmaceutics 336 (2), 208-214, 2007 | 55 | 2007 |
N-Substituted homopiperazine barbiturates as gelatinase inhibitors J Wang, C Medina, MW Radomski, JF Gilmer Bioorganic & medicinal chemistry 19 (16), 4985-4999, 2011 | 50 | 2011 |
Ursodeoxycholic acid amides as novel glucocorticoid receptor modulators R Sharma, D Prichard, F Majer, AM Byrne, D Kelleher, A Long, JF Gilmer Journal of medicinal chemistry 54 (1), 122-130, 2011 | 49 | 2011 |
Discovery of a “true” aspirin prodrug LM Moriarty, MN Lally, CG Carolan, M Jones, JM Clancy, JF Gilmer Journal of medicinal chemistry 51 (24), 7991-7999, 2008 | 46 | 2008 |
The aqueous stability of bupropion PM O’Byrne, R Williams, JJ Walsh, JF Gilmer Journal of pharmaceutical and biomedical analysis 53 (3), 376-381, 2010 | 43 | 2010 |
Isosorbide-2-carbamate esters: potent and selective butyrylcholinesterase inhibitors CG Carolan, GP Dillon, JM Gaynor, S Reidy, SA Ryder, D Khan, ... Journal of medicinal chemistry 51 (20), 6400-6409, 2008 | 41 | 2008 |
Isosorbide-based aspirin prodrugs: II. Hydrolysis kinetics of isosorbide diaspirinate JF Gilmer, LM Moriarty, MN Lally, JM Clancy European journal of pharmaceutical sciences 16 (4-5), 297-304, 2002 | 41 | 2002 |
Ursodeoxycholic acid attenuates colonic epithelial secretory function OB Kelly, MS Mroz, JBJ Ward, C Colliva, M Scharl, R Pellicciari, JF Gilmer, ... The Journal of physiology 591 (9), 2307-2318, 2013 | 40 | 2013 |
Isosorbide-based aspirin prodrugs: integration of nitric oxide releasing groups M Jones, I Inkielewicz, C Medina, MJ Santos-Martinez, A Radomski, ... Journal of medicinal chemistry 52 (21), 6588-6598, 2009 | 40 | 2009 |
Design, synthesis, and pharmacological effects of a cyclization-activated steroid prodrug for colon targeting in inflammatory bowel disease JFM Ruiz, G Radics, H Windle, HO Serra, AL Simplício, K Kedziora, ... Journal of medicinal chemistry 52 (10), 3205-3211, 2009 | 39 | 2009 |
New highly toxic bile acids derived from deoxycholic acid, chenodeoxycholic acid and lithocholic acid F Májer, R Sharma, C Mullins, L Keogh, S Phipps, S Duggan, D Kelleher, ... Bioorganic & medicinal chemistry 22 (1), 256-268, 2014 | 38 | 2014 |