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Sudarsan Rajan
Sudarsan Rajan
Associate Professor, Temple University, Lewis Katz School of Medicine
在 temple.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Circular RNA CircFndc3b modulates cardiac repair after myocardial infarction via FUS/VEGF-A axis
VNS Garikipati, SK Verma, Z Cheng, D Liang, MM Truongcao, M Cimini, ...
Nature communications 10 (1), 4317, 2019
3332019
Mitochondrial Ca2+ uniporter is a mitochondrial luminal redox sensor that augments MCU channel activity
Z Dong, S Shanmughapriya, D Tomar, N Siddiqui, S Lynch, N Nemani, ...
Molecular cell 65 (6), 1014-1028. e7, 2017
2342017
MCUR1 is a scaffold factor for the MCU complex function and promotes mitochondrial bioenergetics
D Tomar, Z Dong, S Shanmughapriya, DA Koch, T Thomas, NE Hoffman, ...
Cell reports 15 (8), 1673-1685, 2016
2272016
Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth
JV Michael, JGT Wurtzel, GF Mao, AK Rao, MA Kolpakov, A Sabri, ...
Blood, The Journal of the American Society of Hematology 130 (5), 567-580, 2017
2172017
SPG7 is an essential and conserved component of the mitochondrial permeability transition pore
S Shanmughapriya, S Rajan, NE Hoffman, AM Higgins, D Tomar, ...
Molecular cell 60 (1), 47-62, 2015
2122015
Ligand‐specific function of transforming growth factor beta in epithelial‐mesenchymal transition in heart development
M Azhar, RB Runyan, C Gard, LP Sanford, ML Miller, A Andringa, ...
Developmental dynamics 238 (2), 431-442, 2009
1582009
SLC25A23 augments mitochondrial Ca2+ uptake, interacts with MCU, and induces oxidative stress–mediated cell death
NE Hoffman, HC Chandramoorthy, S Shanmughapriya, XQ Zhang, ...
Molecular biology of the cell 25 (6), 936-947, 2014
1522014
MICU1 motifs define mitochondrial calcium uniporter binding and activity
NE Hoffman, HC Chandramoorthy, S Shamugapriya, X Zhang, S Rajan, ...
Cell reports 5 (6), 1576-1588, 2013
1492013
Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU
S Shanmughapriya, S Rajan, NE Hoffman, X Zhang, S Guo, JE Kolesar, ...
Science signaling 8 (366), ra23-ra23, 2015
1352015
Dilated cardiomyopathy mutant tropomyosin mice develop cardiac dysfunction with significantly decreased fractional shortening and myofilament calcium sensitivity
S Rajan, RPH Ahmed, G Jagatheesan, N Petrashevskaya, GP Boivin, ...
Circulation research 101 (2), 205-214, 2007
1162007
LETM1-dependent mitochondrial Ca2+ flux modulates cellular bioenergetics and proliferation
PJ Doonan, HC Chandramoorthy, NE Hoffman, X Zhang, C Cárdenas, ...
The FASEB Journal 28 (11), 4936, 2014
1082014
Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform
S Rajan, G Jagatheesan, CN Karam, ML Alves, I Bodi, A Schwartz, ...
Circulation 121 (3), 410-418, 2010
1072010
Loss of adult cardiac myocyte GSK-3 leads to mitotic catastrophe resulting in fatal dilated cardiomyopathy
J Zhou, F Ahmad, S Parikh, NE Hoffman, S Rajan, VK Verma, J Song, ...
Circulation research 118 (8), 1208-1222, 2016
1032016
TRPM2 channels protect against cardiac ischemia-reperfusion injury: role of mitochondria
BA Miller, NE Hoffman, S Merali, XQ Zhang, JF Wang, S Rajan, ...
Journal of Biological Chemistry 289 (11), 7615-7629, 2014
1022014
MIRO-1 determines mitochondrial shape transition upon GPCR activation and Ca2+ stress
N Nemani, E Carvalho, D Tomar, Z Dong, A Ketschek, SL Breves, F Jaña, ...
Cell reports 23 (4), 1005-1019, 2018
962018
Structural insights into mitochondrial calcium uniporter regulation by divalent cations
SK Lee, S Shanmughapriya, MCY Mok, Z Dong, D Tomar, E Carvalho, ...
Cell chemical biology 23 (9), 1157-1169, 2016
892016
Transforming growth factor Beta2 is required for valve remodeling during heart development
M Azhar, K Brown, C Gard, H Chen, S Rajan, DA Elliott, MV Stevens, ...
Developmental Dynamics 240 (9), 2127-2141, 2011
892011
A cellular mechanism of muscle memory facilitates mitochondrial remodelling following resistance training
H Lee, K Kim, B Kim, J Shin, S Rajan, J Wu, X Chen, MD Brown, S Lee, ...
The Journal of physiology 596 (18), 4413-4426, 2018
802018
Blockade of MCU-mediated Ca2+ uptake perturbs lipid metabolism via PP4-dependent AMPK dephosphorylation
D Tomar, F Jaña, Z Dong, WJ Quinn, P Jadiya, SL Breves, CC Daw, ...
Cell reports 26 (13), 3709-3725. e7, 2019
742019
Ca2+ entry via Trpm2 is essential for cardiac myocyte bioenergetics maintenance
NE Hoffman, BA Miller, JF Wang, JW Elrod, S Rajan, E Gao, J Song, ...
American Journal of Physiology-Heart and Circulatory Physiology 308 (6 …, 2015
692015
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