Circular RNA CircFndc3b modulates cardiac repair after myocardial infarction via FUS/VEGF-A axis VNS Garikipati, SK Verma, Z Cheng, D Liang, MM Truongcao, M Cimini, ... Nature communications 10 (1), 4317, 2019 | 333 | 2019 |
Mitochondrial Ca2+ uniporter is a mitochondrial luminal redox sensor that augments MCU channel activity Z Dong, S Shanmughapriya, D Tomar, N Siddiqui, S Lynch, N Nemani, ... Molecular cell 65 (6), 1014-1028. e7, 2017 | 234 | 2017 |
MCUR1 is a scaffold factor for the MCU complex function and promotes mitochondrial bioenergetics D Tomar, Z Dong, S Shanmughapriya, DA Koch, T Thomas, NE Hoffman, ... Cell reports 15 (8), 1673-1685, 2016 | 227 | 2016 |
Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth JV Michael, JGT Wurtzel, GF Mao, AK Rao, MA Kolpakov, A Sabri, ... Blood, The Journal of the American Society of Hematology 130 (5), 567-580, 2017 | 217 | 2017 |
SPG7 is an essential and conserved component of the mitochondrial permeability transition pore S Shanmughapriya, S Rajan, NE Hoffman, AM Higgins, D Tomar, ... Molecular cell 60 (1), 47-62, 2015 | 212 | 2015 |
Ligand‐specific function of transforming growth factor beta in epithelial‐mesenchymal transition in heart development M Azhar, RB Runyan, C Gard, LP Sanford, ML Miller, A Andringa, ... Developmental dynamics 238 (2), 431-442, 2009 | 158 | 2009 |
SLC25A23 augments mitochondrial Ca2+ uptake, interacts with MCU, and induces oxidative stress–mediated cell death NE Hoffman, HC Chandramoorthy, S Shanmughapriya, XQ Zhang, ... Molecular biology of the cell 25 (6), 936-947, 2014 | 152 | 2014 |
MICU1 motifs define mitochondrial calcium uniporter binding and activity NE Hoffman, HC Chandramoorthy, S Shamugapriya, X Zhang, S Rajan, ... Cell reports 5 (6), 1576-1588, 2013 | 149 | 2013 |
Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU S Shanmughapriya, S Rajan, NE Hoffman, X Zhang, S Guo, JE Kolesar, ... Science signaling 8 (366), ra23-ra23, 2015 | 135 | 2015 |
Dilated cardiomyopathy mutant tropomyosin mice develop cardiac dysfunction with significantly decreased fractional shortening and myofilament calcium sensitivity S Rajan, RPH Ahmed, G Jagatheesan, N Petrashevskaya, GP Boivin, ... Circulation research 101 (2), 205-214, 2007 | 116 | 2007 |
LETM1-dependent mitochondrial Ca2+ flux modulates cellular bioenergetics and proliferation PJ Doonan, HC Chandramoorthy, NE Hoffman, X Zhang, C Cárdenas, ... The FASEB Journal 28 (11), 4936, 2014 | 108 | 2014 |
Molecular and functional characterization of a novel cardiac-specific human tropomyosin isoform S Rajan, G Jagatheesan, CN Karam, ML Alves, I Bodi, A Schwartz, ... Circulation 121 (3), 410-418, 2010 | 107 | 2010 |
Loss of adult cardiac myocyte GSK-3 leads to mitotic catastrophe resulting in fatal dilated cardiomyopathy J Zhou, F Ahmad, S Parikh, NE Hoffman, S Rajan, VK Verma, J Song, ... Circulation research 118 (8), 1208-1222, 2016 | 103 | 2016 |
TRPM2 channels protect against cardiac ischemia-reperfusion injury: role of mitochondria BA Miller, NE Hoffman, S Merali, XQ Zhang, JF Wang, S Rajan, ... Journal of Biological Chemistry 289 (11), 7615-7629, 2014 | 102 | 2014 |
MIRO-1 determines mitochondrial shape transition upon GPCR activation and Ca2+ stress N Nemani, E Carvalho, D Tomar, Z Dong, A Ketschek, SL Breves, F Jaña, ... Cell reports 23 (4), 1005-1019, 2018 | 96 | 2018 |
Structural insights into mitochondrial calcium uniporter regulation by divalent cations SK Lee, S Shanmughapriya, MCY Mok, Z Dong, D Tomar, E Carvalho, ... Cell chemical biology 23 (9), 1157-1169, 2016 | 89 | 2016 |
Transforming growth factor Beta2 is required for valve remodeling during heart development M Azhar, K Brown, C Gard, H Chen, S Rajan, DA Elliott, MV Stevens, ... Developmental Dynamics 240 (9), 2127-2141, 2011 | 89 | 2011 |
A cellular mechanism of muscle memory facilitates mitochondrial remodelling following resistance training H Lee, K Kim, B Kim, J Shin, S Rajan, J Wu, X Chen, MD Brown, S Lee, ... The Journal of physiology 596 (18), 4413-4426, 2018 | 80 | 2018 |
Blockade of MCU-mediated Ca2+ uptake perturbs lipid metabolism via PP4-dependent AMPK dephosphorylation D Tomar, F Jaña, Z Dong, WJ Quinn, P Jadiya, SL Breves, CC Daw, ... Cell reports 26 (13), 3709-3725. e7, 2019 | 74 | 2019 |
Ca2+ entry via Trpm2 is essential for cardiac myocyte bioenergetics maintenance NE Hoffman, BA Miller, JF Wang, JW Elrod, S Rajan, E Gao, J Song, ... American Journal of Physiology-Heart and Circulatory Physiology 308 (6 …, 2015 | 69 | 2015 |