Molecular docking characterizes substrate-binding sites and efflux modulation mechanisms within P-glycoprotein. RJ Ferreira, MJU Ferreira, DJVA dos Santos Journal of chemical information and modeling 53 (7), 1747-1760, 2013 | 175 | 2013 |
Inhibition of multidrug resistance of cancer cells by natural diterpenes, triterpenes and carotenoids J Molnár, N Gyémánt, M Tanaka, J Hohmann, E Bergmann-Leitner, ... Current pharmaceutical design 12 (3), 287-311, 2006 | 143 | 2006 |
Insights on P-glycoprotein’s efflux mechanism obtained by molecular dynamics simulations RJ Ferreira, MJU Ferreira, DJVA Dos Santos Journal of Chemical Theory and Computation 8 (6), 1853-1864, 2012 | 136 | 2012 |
Antimycobacterial evaluation and preliminary phytochemical investigation of selected medicinal plants traditionally used in Mozambique X Luo, D Pires, JA Aínsa, B Gracia, S Mulhovo, A Duarte, E Anes, ... Journal of Ethnopharmacology 137 (1), 114-120, 2011 | 114 | 2011 |
Evaluation of the Antiviral and Antimicrobial Activities of Triterpenes Isolated from Euphorbia segetalis AM Madureira, JR Ascenso, L Valdeira, A Duarte, JP Frade, G Freitas, ... Natural Product Research 17 (5), 375-380, 2003 | 113 | 2003 |
Apoptosis induction and modulation of P-glycoprotein mediated multidrug resistance by new macrocyclic lathyrane-type diterpenoids N Duarte, A Varga, G Cherepnev, R Radics, J Molnár, MJU Ferreira Bioorganic & Medicinal Chemistry 15 (1), 546-554, 2007 | 108 | 2007 |
Antitumor activity of terpenoids against classical and atypical multidrug resistant cancer cells H Lage, N Duarte, C Coburger, A Hilgeroth, MJU Ferreira Phytomedicine 17 (6), 441-448, 2010 | 103 | 2010 |
Bioactive Diterpenoids, a New Jatrophane and Two ent-Abietanes, and Other Constituents from Euphorbia pubescens C Valente, M Pedro, A Duarte, MSJ Nascimento, PM Abreu, MJU Ferreira Journal of natural products 67 (5), 902-904, 2004 | 94 | 2004 |
P-glycoprotein and membrane roles in multidrug resistance RJ Ferreira, DJVA dos Santos, MJU Ferreira Future medicinal chemistry 7 (7), 929-946, 2015 | 88 | 2015 |
New macrocyclic lathyrane diterpenes, from Euphorbia lagascae, as inhibitors of multidrug resistance of tumour cells N Duarte, N Gyémánt, PM Abreu, J Molnár, MJU Ferreira Planta medica 72 (02), 162-168, 2006 | 85 | 2006 |
Antibacterial activity of some African medicinal plants used traditionally against infectious diseases AM Madureira, C Ramalhete, S Mulhovo, A Duarte, MJU Ferreira Pharmaceutical Biology 50 (4), 481-489, 2012 | 82 | 2012 |
Zanthoxylum capense constituents with antimycobacterial activity against Mycobacterium tuberculosis in vitro and ex vivo within human macrophages X Luo, D Pires, JA Aínsa, B Gracia, N Duarte, S Mulhovo, E Anes, ... Journal of ethnopharmacology 146 (1), 417-422, 2013 | 81 | 2013 |
Multidrug Resistance Reversal and Apoptosis Induction in Human Colon Cancer Cells by Some Flavonoids Present in Citrus Plants O Wesołowska, J Wiśniewski, K Środa-Pomianek, A Bielawska-Pohl, ... Journal of natural products 75 (11), 1896-1902, 2012 | 80 | 2012 |
Isoflavones as apoptosis inducers in human hepatoma HuH‐7 cells TA Mansoor, RM Ramalho, X Luo, C Ramalhete, CMP Rodrigues, ... Phytotherapy Research 25 (12), 1819-1824, 2011 | 76 | 2011 |
Inhibition of efflux pumps in meticillin-resistant Staphylococcus aureus and Enterococcus faecalis resistant strains by triterpenoids from Momordica balsamina C Ramalhete, G Spengler, A Martins, M Martins, M Viveiros, S Mulhovo, ... International Journal of Antimicrobial Agents 37 (1), 70-74, 2011 | 75 | 2011 |
Enhancing macrocyclic diterpenes as multidrug-resistance reversers: structure–activity studies on jolkinol D derivatives M Reis, RJ Ferreira, MMM Santos, DJVA dos Santos, J Molnár, ... Journal of Medicinal Chemistry 56 (3), 748-760, 2013 | 72 | 2013 |
Induction of apoptosis in HuH-7 cancer cells by monoterpene and β-carboline indole alkaloids isolated from the leaves of Tabernaemontana elegans TA Mansoor, RM Ramalho, S Mulhovo, CMP Rodrigues, MJU Ferreira Bioorganic & medicinal chemistry letters 19 (15), 4255-4258, 2009 | 71 | 2009 |
Antiplasmodial activity of lignans and extracts from Pycnanthus angolensis M Abrantes, T Mil-Homens, N Duarte, D Lopes, P Cravo, ... Planta medica, 1408-1412, 2008 | 69 | 2008 |
Toward a Better Pharmacophore Description of P-Glycoprotein Modulators, Based on Macrocyclic Diterpenes from Euphorbia Species RJ Ferreira, DJVA dos Santos, MJU Ferreira, RC Guedes Journal of chemical information and modeling 51 (6), 1315-1324, 2011 | 65 | 2011 |
Interaction between doxorubicin and the resistance modifier stilbene on multidrug resistant mouse lymphoma and human breast cancer cells MJU Ferreira, N Duarte, N Gyemant, R Radics, G Cherepnev, A Varga, ... Anticancer research 26 (5A), 3541-3546, 2006 | 64 | 2006 |