Dnm1 forms spirals that are structurally tailored to fit mitochondria E Ingerman, EM Perkins, M Marino, JA Mears, JM McCaffery, JE Hinshaw, ... The Journal of cell biology 170 (7), 1021, 2005 | 708 | 2005 |
Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission JA Mears, LL Lackner, S Fang, E Ingerman, J Nunnari, JE Hinshaw Nature structural & molecular biology 18 (1), 20-26, 2011 | 513 | 2011 |
Structural insights into oligomerization and mitochondrial remodelling of dynamin 1‐like protein C Fröhlich, S Grabiger, D Schwefel, K Faelber, E Rosenbaum, J Mears, ... The EMBO journal 32 (9), 1280-1292, 2013 | 325 | 2013 |
A pseudoatomic model of the dynamin polymer identifies a hydrolysis-dependent powerstroke JS Chappie, JA Mears, S Fang, M Leonard, SL Schmid, RA Milligan, ... Cell 147 (1), 209-222, 2011 | 260 | 2011 |
Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues TA Schulz, MG Choi, S Raychaudhuri, JA Mears, R Ghirlando, ... The Journal of cell biology 187 (6), 889, 2009 | 239 | 2009 |
Modeling a minimal ribosome based on comparative sequence analysis JA Mears, JJ Cannone, SM Stagg, RR Gutell, RK Agrawal, SC Harvey Journal of molecular biology 321 (2), 215-234, 2002 | 202 | 2002 |
Cardiolipin's propensity for phase transition and its reorganization by dynamin-related protein 1 form a basis for mitochondrial membrane fission N Stepanyants, PJ Macdonald, CA Francy, JA Mears, X Qi, ... Molecular biology of the cell 26 (17), 3104-3116, 2015 | 178 | 2015 |
A dimeric equilibrium intermediate nucleates Drp1 reassembly on mitochondrial membranes for fission PJ Macdonald, N Stepanyants, N Mehrotra, JA Mears, X Qi, H Sesaki, ... Molecular biology of the cell 25 (12), 1905-1915, 2014 | 176 | 2014 |
A corkscrew model for dynamin constriction JA Mears, P Ray, JE Hinshaw Structure 15 (10), 1190-1202, 2007 | 135 | 2007 |
The mechanoenzymatic core of dynamin-related protein 1 comprises the minimal machinery required for membrane constriction CA Francy, FJD Alvarez, L Zhou, R Ramachandran, JA Mears Journal of Biological Chemistry 290 (18), 11692-11703, 2015 | 125 | 2015 |
A structural model for the large subunit of the mammalian mitochondrial ribosome JA Mears, MR Sharma, RR Gutell, AS McCook, PE Richardson, ... Journal of molecular biology 358 (1), 193-212, 2006 | 106 | 2006 |
Distinct splice variants of dynamin-related protein 1 differentially utilize mitochondrial fission factor as an effector of cooperative GTPase activity PJ Macdonald, CA Francy, N Stepanyants, L Lehman, A Baglio, JA Mears, ... Journal of Biological Chemistry 291 (1), 493-507, 2016 | 101 | 2016 |
Cryo-EM studies of Drp1 reveal cardiolipin interactions that activate the helical oligomer CA Francy, RW Clinton, C Fröhlich, C Murphy, JA Mears Scientific reports 7 (1), 10744, 2017 | 100 | 2017 |
Dynamin-related protein 1 oligomerization in solution impairs functional interactions with membrane-anchored mitochondrial fission factor RW Clinton, CA Francy, R Ramachandran, X Qi, JA Mears Journal of Biological Chemistry 291 (1), 478-492, 2016 | 98 | 2016 |
Mitochondrial dysfunction in primary ovarian insufficiency D Tiosano, JA Mears, DA Buchner Endocrinology 160 (10), 2353-2366, 2019 | 59 | 2019 |
A structural model for the assembly of the 30 S subunit of the ribosome SM Stagg, JA Mears, SC Harvey Journal of molecular biology 328 (1), 49-61, 2003 | 56 | 2003 |
GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity DC Watson, D Bayik, S Storevik, SS Moreino, SA Sprowls, J Han, ... Nature cancer 4 (5), 648-664, 2023 | 55 | 2023 |
Cryo-electron microscopy structure of the 30S subunit in complex with the YjeQ biogenesis factor A Jomaa, G Stewart, JA Mears, I Kireeva, ED Brown, J Ortega Rna 17 (11), 2026-2038, 2011 | 38 | 2011 |
Steric interference from intrinsically disordered regions controls dynamin-related protein 1 self-assembly during mitochondrial fission B Lu, B Kennedy, RW Clinton, EJ Wang, D McHugh, N Stepanyants, ... Scientific reports 8 (1), 10879, 2018 | 37 | 2018 |
Blocked O-GlcNAc cycling alters mitochondrial morphology, function, and mass EO Akinbiyi, LK Abramowitz, BL Bauer, MSK Stoll, CL Hoppel, CP Hsiao, ... Scientific Reports 11 (1), 22106, 2021 | 34 | 2021 |