Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use M Liu, Y Jiang, R Wedow, Y Li, DM Brazel, F Chen, G Datta, ... Nature genetics 51 (2), 237-244, 2019 | 1544 | 2019 |
Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial AF Hernandez, JB Green, S Janmohamed, RB D'Agostino, CB Granger, ... The Lancet 392 (10157), 1519-1529, 2018 | 1388 | 2018 |
An atlas of genetic influences on osteoporosis in humans and mice JA Morris, JP Kemp, SE Youlten, L Laurent, JG Logan, RC Chai, ... Nature genetics 51 (2), 258-266, 2019 | 641 | 2019 |
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences R Karlsson Linnér, P Biroli, E Kong, SFW Meddens, R Wedow, ... Nature genetics 51 (2), 245-257, 2019 | 613 | 2019 |
A genetic investigation of sex bias in the prevalence of attention-deficit/hyperactivity disorder J Martin, RK Walters, D Demontis, M Mattheisen, SH Lee, E Robinson, ... Biological psychiatry 83 (12), 1044-1053, 2018 | 183 | 2018 |
Placenta and appetite genes GDF15 and IGFBP7 are associated with hyperemesis gravidarum MS Fejzo, OV Sazonova, JF Sathirapongsasuti, IB Hallgrímsdóttir, V Vacic, ... Nature communications 9 (1), 1178, 2018 | 155 | 2018 |
Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells EL Bao, SK Nandakumar, X Liao, AG Bick, J Karjalainen, M Tabaka, ... Nature 586 (7831), 769-775, 2020 | 111 | 2020 |
Common variant burden contributes to the familial aggregation of migraine in 1,589 families P Gormley, MI Kurki, ME Hiekkala, K Veerapen, P Häppölä, AA Mitchell, ... Neuron 98 (4), 743-753. e4, 2018 | 97 | 2018 |
Cell-cell interactions mediate the response of vascular smooth muscle cells to substrate stiffness OV Sazonova, KL Lee, BC Isenberg, CB Rich, MA Nugent, JY Wong Biophysical journal 101 (3), 622-630, 2011 | 97 | 2011 |
Extracellular matrix presentation modulates vascular smooth muscle cell mechanotransduction OV Sazonova, BC Isenberg, J Herrmann, KL Lee, A Purwada, ... Matrix Biology 41, 36-43, 2015 | 96 | 2015 |
The effect of stromal components on the modulation of the phenotype of human bronchial epithelial cells in 3D culture SC Pageau, OV Sazonova, JY Wong, AM Soto, C Sonnenschein Biomaterials 32 (29), 7169-7180, 2011 | 72 | 2011 |
TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth … JB Kim, M Pjanic, T Nguyen, CL Miller, D Iyer, B Liu, T Wang, O Sazonova, ... PLoS Genetics 13 (5), e1006750, 2017 | 62 | 2017 |
Thermo-responsive poly (N-isopropylacrylamide) grafted onto microtextured poly (dimethylsiloxane) for aligned cell sheet engineering JB Lin, BC Isenberg, Y Shen, K Schorsch, OV Sazonova, JY Wong Colloids and Surfaces B: Biointerfaces 99, 108-115, 2012 | 57 | 2012 |
Characterization of TCF21 downstream target regions identifies a transcriptional network linking multiple independent coronary artery disease loci O Sazonova, Y Zhao, S Nürnberg, C Miller, M Pjanic, VG Castano, JB Kim, ... PLoS genetics 11 (5), e1005202, 2015 | 54 | 2015 |
Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan B Hollis, FR Day, AS Busch, DJ Thompson, ALG Soares, PRHJ Timmers, ... Nature communications 11 (1), 1536, 2020 | 52 | 2020 |
Comparison of biphasic insulin aspart 30 given three times daily or twice daily in combination with metformin versus oral antidiabetic drugs alone in patients with poorly … O Ushakova, V Sokolovskaya, A Morozova, F Valeeva, O Zanozina, ... Clinical therapeutics 29 (11), 2374-2384, 2007 | 49 | 2007 |
Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease T Zheng, D Ellinghaus, S Juzenas, F Cossais, G Burmeister, G Mayr, ... Gut 70 (8), 1538-1549, 2021 | 32 | 2021 |
Association of whole-genome and NETRIN1 signaling pathway–derived polygenic risk scores for major depressive disorder and white matter microstructure in the UK Biobank MC Barbu, Y Zeng, X Shen, SR Cox, TK Clarke, J Gibson, MJ Adams, ... Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 4 (1), 91-100, 2019 | 28 | 2019 |
Overlapping genetic architecture between Parkinson disease and melanoma U Dube, L Ibanez, JP Budde, BA Benitez, AA Davis, O Harari, MM Iles, ... Acta neuropathologica 139, 347-364, 2020 | 27 | 2020 |
Genetic overlap analysis of endometriosis and asthma identifies shared loci implicating sex hormones and thyroid signalling pathways EO Adewuyi, D Mehta, DR Nyholt Human Reproduction 37 (2), 366-383, 2022 | 20 | 2022 |