| Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study NA Kennedy, GA Heap, HD Green, B Hamilton, C Bewshea, GJ Walker, ... The lancet Gastroenterology & hepatology 4 (5), 341-353, 2019 | 577 | 2019 |
| Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease SE Flanagan, E Haapaniemi, MA Russell, R Caswell, HL Allen, ... Nature genetics 46 (8), 812-814, 2014 | 517 | 2014 |
| The development and validation of a clinical prediction model to determine the probability of MODY in patients with young-onset diabetes BM Shields, TJ McDonald, S Ellard, MJ Campbell, C Hyde, AT Hattersley Diabetologia 55, 1265-1272, 2012 | 369 | 2012 |
| The majority of patients with long-duration type 1 diabetes are insulin microsecretors and have functioning beta cells RA Oram, AG Jones, REJ Besser, BA Knight, BM Shields, RJ Brown, ... Diabetologia 57, 187-191, 2014 | 337 | 2014 |
| A type 1 diabetes genetic risk score can aid discrimination between type 1 and type 2 diabetes in young adults RA Oram, K Patel, A Hill, B Shields, TJ McDonald, A Jones, AT Hattersley, ... Diabetes care 39 (3), 337-344, 2016 | 336 | 2016 |
| HLA-DQA1* 05 carriage associated with development of anti-drug antibodies to infliximab and adalimumab in patients with Crohn’s disease A Sazonovs, NA Kennedy, L Moutsianas, GA Heap, DL Rice, M Reppell, ... Gastroenterology 158 (1), 189-199, 2020 | 313 | 2020 |
| Islet autoantibodies can discriminate maturity‐onset diabetes of the young (MODY) from Type 1 diabetes TJ McDonald, K Colclough, R Brown, B Shields, M Shepherd, P Bingley, ... Diabetic Medicine 28 (9), 1028-1033, 2011 | 285 | 2011 |
| Infliximab is associated with attenuated immunogenicity to BNT162b2 and ChAdOx1 nCoV-19 SARS-CoV-2 vaccines in patients with IBD NA Kennedy, S Lin, JR Goodhand, N Chanchlani, B Hamilton, ... Gut 70 (10), 1884-1893, 2021 | 259 | 2021 |
| Systematic population screening, using biomarkers and genetic testing, identifies 2.5% of the UK pediatric diabetes population with monogenic diabetes M Shepherd, B Shields, S Hammersley, M Hudson, TJ McDonald, ... Diabetes care 39 (11), 1879-1888, 2016 | 242 | 2016 |
| Maturity onset diabetes of the young: identification and diagnosis TJ McDonald, S Ellard Annals of clinical biochemistry 50 (5), 403-415, 2013 | 207 | 2013 |
| Markers of β-cell failure predict poor glycemic response to GLP-1 receptor agonist therapy in type 2 diabetes AG Jones, TJ McDonald, BM Shields, AV Hill, CJ Hyde, BA Knight, ... Diabetes care 39 (2), 250-257, 2016 | 180 | 2016 |
| Anti-SARS-CoV-2 antibody responses are attenuated in patients with IBD treated with infliximab NA Kennedy, JR Goodhand, C Bewshea, R Nice, D Chee, S Lin, ... Gut 70 (5), 865-875, 2021 | 179 | 2021 |
| Most people with long-duration type 1 diabetes in a large population-based study are insulin microsecretors RA Oram, TJ McDonald, BM Shields, MM Hudson, MH Shepherd, ... Diabetes care 38 (2), 323-328, 2015 | 152 | 2015 |
| Urinary C-peptide creatinine ratio is a practical outpatient tool for identifying hepatocyte nuclear factor 1-α/hepatocyte nuclear factor 4-α maturity-onset diabetes of the … REJ Besser, MH Shepherd, TJ McDonald, BM Shields, BA Knight, ... Diabetes care 34 (2), 286-291, 2011 | 151 | 2011 |
| Population-based assessment of a biomarker-based screening pathway to aid diagnosis of monogenic diabetes in young-onset patients BM Shields, M Shepherd, M Hudson, TJ McDonald, K Colclough, J Peters, ... Diabetes Care 40 (8), 1017-1025, 2017 | 145 | 2017 |
| Type 1 diabetes defined by severe insulin deficiency occurs after 30 years of age and is commonly treated as type 2 diabetes NJ Thomas, AL Lynam, AV Hill, MN Weedon, BM Shields, RA Oram, ... Diabetologia 62 (7), 1167-1172, 2019 | 138 | 2019 |
| Studies of insulin and proinsulin in pancreas and serum support the existence of aetiopathological endotypes of type 1 diabetes associated with age at diagnosis P Leete, RA Oram, TJ McDonald, BM Shields, C Ziller, ... Diabetologia 63, 1258-1267, 2020 | 126 | 2020 |
| High-sensitivity CRP discriminates HNF1A-MODY from other subtypes of diabetes TJ McDonald, BM Shields, J Lawry, KR Owen, AL Gloyn, S Ellard, ... Diabetes care 34 (8), 1860-1862, 2011 | 122 | 2011 |
| The HNF4A R76W mutation causes atypical dominant Fanconi syndrome in addition to a β cell phenotype AJ Hamilton, C Bingham, TJ McDonald, PR Cook, RC Caswell, ... Journal of medical genetics 51 (3), 165-169, 2014 | 112 | 2014 |
| C-peptide decline in type 1 diabetes has two phases: an initial exponential fall and a subsequent stable phase BM Shields, TJ McDonald, R Oram, A Hill, M Hudson, P Leete, ... Diabetes care 41 (7), 1486-1492, 2018 | 105 | 2018 |
Professor Andrew HattersleyUniversity of Exeter在 exeter.ac.uk 的电子邮件经过验证
