8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes GT and AC substitutions. KC Cheng, DS Cahill, H Kasai, S Nishimura, LA Loeb Journal of biological chemistry 267 (1), 166-172, 1992 | 2415 | 1992 |
Mutator phenotype may be required for multistage carcinogenesis LA Loeb Cancer research 51 (12), 3075-3079, 1991 | 1885 | 1991 |
Fidelity of HIV-1 reverse transcriptase BD Preston, BJ Poiesz, LA Loeb Science 242 (4882), 1168-1171, 1988 | 1387 | 1988 |
Mutagenesis by apurinic/apyrimidinic sites LA Loeb, BD Preston Annual review of genetics 20 (1), 201-230, 1986 | 1257 | 1986 |
Detection of ultra-rare mutations by next-generation sequencing MW Schmitt, SR Kennedy, JJ Salk, EJ Fox, JB Hiatt, LA Loeb Proceedings of the National Academy of Sciences 109 (36), 14508-14513, 2012 | 1156 | 2012 |
Multiple mutations and cancer LA Loeb, KR Loeb, JP Anderson Proceedings of the National Academy of Sciences 100 (3), 776-781, 2003 | 1116 | 2003 |
A mutator phenotype in cancer LA Loeb Cancer research 61 (8), 3230-3239, 2001 | 1080 | 2001 |
Environmental and chemical carcinogenesis GN Wogan, SS Hecht, JS Felton, AH Conney, LA Loeb Seminars in cancer biology 14 (6), 473-486, 2004 | 893 | 2004 |
The contribution of endogenous sources of DNA damage to the multiple mutations in cancer AL Jackson, LA Loeb Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 477 (1 …, 2001 | 882 | 2001 |
Reactive oxygen species in tumorigenesis DI Feig, TM Reid, LA Loeb Cancer research 54 (7_Supplement), 1890s-1894s, 1994 | 798 | 1994 |
Protein tolerance to random amino acid change HH Guo, J Choe, LA Loeb Proceedings of the National Academy of Sciences 101 (25), 9205-9210, 2004 | 778 | 2004 |
Microsatellite instability: marker of a mutator phenotype in cancer LA Loeb Cancer research 54, 5059-5059, 1994 | 766 | 1994 |
The Werner syndrome protein is a DNA helicase MD Gray, JC Shen, AS Kamath-Loeb, A Blank, BL Sopher, GM Martin, ... Nature genetics 17 (1), 100-103, 1997 | 740 | 1997 |
Fidelity of DNA synthesis LA Loeb, TA Kunkel Annual review of biochemistry 51 (1), 429-457, 1982 | 695 | 1982 |
Errors in DNA replication as a basis of malignant changes LA Loeb, CF Springgate, N Battula Cancer research 34 (9), 2311-2321, 1974 | 670 | 1974 |
Significance of multiple mutations in cancer KR Loeb, LA Loeb Carcinogenesis 21 (3), 379-385, 2000 | 631 | 2000 |
Detecting ultralow-frequency mutations by Duplex Sequencing SR Kennedy, MW Schmitt, EJ Fox, BF Kohrn, JJ Salk, EH Ahn, MJ Prindle, ... Nature protocols 9 (11), 2586-2606, 2014 | 561 | 2014 |
Infidelity of DNA synthesis in vitro: screening for potential metal mutagens or carcinogens MA Sirover, LA Loeb Science 194 (4272), 1434-1436, 1976 | 560 | 1976 |
Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging DF Dai, LF Santana, M Vermulst, DM Tomazela, MJ Emond, MJ MacCoss, ... Circulation 119 (21), 2789-2797, 2009 | 538 | 2009 |
Human cancers express mutator phenotypes: origin, consequences and targeting LA Loeb Nature Reviews Cancer 11 (6), 450-457, 2011 | 499 | 2011 |