An aquaporin-4/transient receptor potential vanilloid 4 (AQP4/TRPV4) complex is essential for cell-volume control in astrocytes V Benfenati, M Caprini, M Dovizio, MN Mylonakou, S Ferroni, OP Ottersen, ... Proceedings of the National Academy of Sciences 108 (6), 2563-2568, 2011 | 388 | 2011 |
Aspirin prevents colorectal cancer metastasis in mice by splitting the crosstalk between platelets and tumor cells P Guillem-Llobat, M Dovizio, A Bruno, E Ricciotti, V Cufino, A Sacco, ... Oncotarget 7 (22), 32462, 2016 | 175 | 2016 |
Mode of action of aspirin as a chemopreventive agent M Dovizio, A Bruno, S Tacconelli, P Patrignani Prospects for Chemoprevention of Colorectal Neoplasia: Emerging Role of Anti …, 2013 | 154 | 2013 |
Pharmacological inhibition of platelet-tumor cell cross-talk prevents platelet-induced overexpression of cyclooxygenase-2 in HT29 human colon carcinoma cells M Dovizio, TJ Maier, S Alberti, L Di Francesco, E Marcantoni, G Münch, ... Molecular pharmacology 84 (1), 25-40, 2013 | 124 | 2013 |
Reappraisal of the clinical pharmacology of low‐dose aspirin by comparing novel direct and traditional indirect biomarkers of drug action P Patrignani, S Tacconelli, E Piazuelo, L Di Francesco, M Dovizio, ... Journal of Thrombosis and Haemostasis 12 (8), 1320-1330, 2014 | 109 | 2014 |
Role of platelets in inflammation and cancer: novel therapeutic strategies M Dovizio, S Alberti, P Guillem‐Llobat, P Patrignani Basic & clinical pharmacology & toxicology 114 (1), 118-127, 2014 | 105 | 2014 |
Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis factor-α biosynthesis via heme oxygenase-1 in human endothelial cells L Di Francesco, L Totani, M Dovizio, A Piccoli, A Di Francesco, ... Circulation research 104 (4), 506-513, 2009 | 105 | 2009 |
Synthesis, pharmacological characterization, and docking analysis of a novel family of diarylisoxazoles as highly selective cyclooxygenase-1 (COX-1) inhibitors P Vitale, S Tacconelli, MG Perrone, P Malerba, L Simone, A Scilimati, ... Journal of Medicinal Chemistry 56 (11), 4277-4299, 2013 | 101 | 2013 |
Mechanistic and pharmacological issues of aspirin as an anticancer agent M Dovizio, S Tacconelli, C Sostres, E Ricciotti, P Patrignani Pharmaceuticals 5 (12), 1346-1371, 2012 | 100 | 2012 |
Carbenoxolone inhibits volume-regulated anion conductance in cultured rat cortical astroglia V Benfenati, M Caprini, GP Nicchia, A Rossi, M Dovizio, C Cervetto, ... Channels 3 (5), 323-336, 2009 | 90 | 2009 |
Platelets as crucial partners for tumor metastasis: from mechanistic aspects to pharmacological targeting A Contursi, A Sacco, R Grande, M Dovizio, P Patrignani Cellular and Molecular Life Sciences 74, 3491-3507, 2017 | 80 | 2017 |
P2Y12 Receptors in Tumorigenesis and Metastasis P Ballerini, M Dovizio, A Bruno, S Tacconelli, P Patrignani Frontiers in Pharmacology 9, 66, 2018 | 75 | 2018 |
Effects of AF3442 [N-(9-ethyl-9H-carbazol-3-yl)-2-(trifluoromethyl) benzamide], a novel inhibitor of human microsomal prostaglandin E synthase-1, on prostanoid biosynthesis in … A Bruno, L Di Francesco, I Coletta, G Mangano, MA Alisi, L Polenzani, ... Biochemical pharmacology 79 (7), 974-981, 2010 | 67 | 2010 |
Platelets and extracellular vesicles in cancer: diagnostic and therapeutic implications M Dovizio, A Bruno, A Contursi, R Grande, P Patrignani Cancer and Metastasis Reviews 37, 455-467, 2018 | 64 | 2018 |
Platelet-derived microparticles from obese individuals: characterization of number, size, proteomics, and crosstalk with cancer and endothelial cells R Grande, M Dovizio, S Marcone, PB Szklanna, A Bruno, HA Ebhardt, ... Frontiers in pharmacology 10, 7, 2019 | 54 | 2019 |
Platelets in cancer development and diagnosis A Contursi, R Grande, M Dovizio, A Bruno, R Fullone, P Patrignani Biochemical Society Transactions 46 (6), 1517-1527, 2018 | 49 | 2018 |
Platelets, cyclooxygenases, and colon cancer P Guillem-Llobat, M Dovizio, S Alberti, A Bruno, P Patrignani Seminars in oncology 41 (3), 385-396, 2014 | 49 | 2014 |
Multifaceted functions of platelets in cancer: from tumorigenesis to liquid biopsy tool and drug delivery system M Dovizio, P Ballerini, R Fullone, S Tacconelli, A Contursi, P Patrignani International Journal of Molecular Sciences 21 (24), 9585, 2020 | 48 | 2020 |
Low‐dose aspirin acetylates cyclooxygenase‐1 in human colorectal mucosa: implications for the chemoprevention of colorectal cancer P Patrignani, A Sacco, C Sostres, A Bruno, M Dovizio, E Piazuelo, ... Clinical Pharmacology & Therapeutics 102 (1), 52-61, 2017 | 48 | 2017 |
Novel analgesic/anti-inflammatory agents: 1, 5-diarylpyrrole nitrooxyalkyl ethers and related compounds as cyclooxygenase-2 inhibiting nitric oxide donors M Anzini, A Di Capua, S Valenti, S Brogi, M Rovini, G Giuliani, A Cappelli, ... Journal of medicinal chemistry 56 (8), 3191-3206, 2013 | 47 | 2013 |