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Martin Scanlon
Martin Scanlon
Professor of Medicinal Chemistry, Monash University
在 monash.edu 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
JM Hildebrand, MC Tanzer, IS Lucet, SN Young, SK Spall, P Sharma, ...
Proceedings of the National Academy of Sciences 111 (42), 15072-15077, 2014
5682014
DSB proteins and bacterial pathogenicity
B Heras, SR Shouldice, M Totsika, MJ Scanlon, MA Schembri, JL Martin
Nature Reviews Microbiology 7 (3), 215-225, 2009
3402009
Isolation, Solution Structure, and Insecticidal Activity of Kalata B2, a Circular Protein with a Twist:  Do Möbius Strips Exist in Nature?,
CV Jennings, KJ Rosengren, NL Daly, M Plan, J Stevens, MJ Scanlon, ...
Biochemistry 44 (3), 851-860, 2005
2842005
Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor.
NL Daly, MJ Scanlon, JT Djordjevic, PA Kroon, R Smith
Proceedings of the National Academy of Sciences 92 (14), 6334-6338, 1995
2241995
Conformational selection of inhibitors and substrates by proteolytic enzymes: implications for drug design and polypeptide processing
DP Fairlie, JDA Tyndall, RC Reid, AK Wong, G Abbenante, MJ Scanlon, ...
Journal of Medicinal Chemistry 43 (7), 1271-1281, 2000
2162000
Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief
DD Jensen, TM Lieu, ML Halls, NA Veldhuis, WL Imlach, QN Mai, ...
Science Translational Medicine 9 (392), eaal3447, 2017
1982017
Targeting virulence not viability in the search for future antibacterials
B Heras, MJ Scanlon, JL Martin
British journal of clinical pharmacology 79 (2), 208-215, 2015
1932015
The three-dimensional solution structure of NaD1, a new floral defensin from Nicotiana alata and its application to a homology model of the crop defense protein alfAFP
FT Lay, HJ Schirra, MJ Scanlon, MA Anderson, DJ Craik
Journal of Molecular Biology 325 (1), 175-188, 2003
1752003
The cysteine-rich secretory protein domain of Tpx-1 is related to ion channel toxins and regulates ryanodine receptor Ca2+ signaling
GM Gibbs, MJ Scanlon, J Swarbrick, S Curtis, E Gallant, AF Dulhunty, ...
Journal of Biological Chemistry 281 (7), 4156-4163, 2006
1622006
Fatty acid-binding protein 5 facilitates the blood–brain barrier transport of docosahexaenoic acid
Y Pan, MJ Scanlon, Y Owada, Y Yamamoto, CJH Porter, JA Nicolazzo
Molecular pharmaceutics 12 (12), 4375-4385, 2015
1202015
Solution structure and proposed binding mechanism of a novel potassium channel toxin κ-conotoxin PVIIA
MJ Scanlon, D Naranjo, L Thomas, PF Alewood, RJ Lewis, DJ Craik
Structure 5 (12), 1585-1597, 1997
1121997
A Backbone Linker for BOC-Based Peptide Synthesis and On-Resin Cyclization:  Synthesis of Stylostatin 1,
GT Bourne, WDF Meutermans, PF Alewood, RP McGeary, M Scanlon, ...
The Journal of Organic Chemistry 64 (9), 3095-3101, 1999
1081999
Difficult macrocyclizations: New strategies for synthesizing highly strained cyclic tetrapeptides
WDF Meutermans, GT Bourne, SW Golding, DA Horton, MR Campitelli, ...
Organic Letters 5 (15), 2711-2714, 2003
1072003
The ways and means of fragment-based drug design
BC Doak, RS Norton, MJ Scanlon
Pharmacology & therapeutics 167, 28-37, 2016
982016
Small heat-shock proteins interact with a flanking domain to suppress polyglutamine aggregation
AL Robertson, SJ Headey, HM Saunders, H Ecroyd, MJ Scanlon, ...
Proceedings of the National Academy of Sciences 107 (23), 10424-10429, 2010
942010
Promiscuous 2-aminothiazoles (PrATs): a frequent hitting scaffold
SM Devine, MD Mulcair, CO Debono, EWW Leung, JWM Nissink, SS Lim, ...
Journal of medicinal chemistry 58 (3), 1205-1214, 2015
932015
Structural and functional analysis of the Josephin domain of the polyglutamine protein ataxin-3
MKM Chow, JP Mackay, JC Whisstock, MJ Scanlon, SP Bottomley
Biochemical and biophysical research communications 322 (2), 387-394, 2004
932004
Characterization of the drug binding specificity of rat liver fatty acid binding protein
S Chuang, T Velkov, J Horne, CJH Porter, MJ Scanlon
Journal of medicinal chemistry 51 (13), 3755-3764, 2008
882008
The structure of the bacterial oxidoreductase enzyme DsbA in complex with a peptide reveals a basis for substrate specificity in the catalytic cycle of DsbA enzymes
JJ Paxman, NA Borg, J Horne, PE Thompson, Y Chin, P Sharma, ...
Journal of biological chemistry 284 (26), 17835-17845, 2009
832009
Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?
J Wielens, SJ Headey, DI Rhodes, RJ Mulder, O Dolezal, JJ Deadman, ...
Journal of Biomolecular Screening 18 (2), 147-159, 2013
812013
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