Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: a combined analysis of 22 studies A Antoniou, PDP Pharoah, S Narod, HA Risch, JE Eyfjord, JL Hopper, ... The American Journal of Human Genetics 72 (5), 1117-1130, 2003 | 4758 | 2003 |
Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors A Kallioniemi, OP Kallioniemi, D Sudar, D Rutovitz, JW Gray, F Waldman, ... Science 258 (5083), 818-821, 1992 | 4459 | 1992 |
Gene-expression profiles in hereditary breast cancer I Hedenfalk, D Duggan, Y Chen, M Radmacher, M Bittner, R Simon, ... New England Journal of Medicine 344 (8), 539-548, 2001 | 2163 | 2001 |
AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer SL Anzick, J Kononen, RL Walker, DO Azorsa, MM Tanner, XY Guan, ... Science 277 (5328), 965-968, 1997 | 2113 | 1997 |
High frequency of BRAF mutations in nevi PM Pollock, UL Harper, KS Hansen, LM Yudt, M Stark, CM Robbins, ... Nature genetics 33 (1), 19-20, 2003 | 2045 | 2003 |
In vivo amplification of the androgen receptor gene and progression of human prostate cancer T Visakorpi, E Hyytinen, P Koivisto, M Tanner, R Keinänen, C Palmberg, ... Nature genetics 9 (4), 401-406, 1995 | 1986 | 1995 |
Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors OP Kallioniemi, A Kallioniemi, J Piper, J Isola, FM Waldman, JW Gray, ... Genes, Chromosomes and Cancer 10 (4), 231-243, 1994 | 1218 | 1994 |
Major susceptibility locus for prostate cancer on chromosome 1 suggested by a genome-wide search JR Smith, D Freije, JD Carpten, H Grönberg, J Xu, SD Isaacs, ... Science 274 (5291), 1371-1374, 1996 | 1053 | 1996 |
Androgen receptor gene amplification: a possible molecular mechanism for androgen deprivation therapy failure in prostate cancer P Koivisto, J Kononen, C Palmberg, T Tammela, E Hyytinen, J Isola, ... Cancer research 57 (2), 314-319, 1997 | 1015 | 1997 |
Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization. A Kallioniemi, OP Kallioniemi, J Piper, M Tanner, T Stokke, L Chen, ... Proceedings of the National Academy of Sciences 91 (6), 2156-2160, 1994 | 916 | 1994 |
Survey of gene amplifications during prostate cancer progression by high-throughput fluorescence in situ hybridization on tissue microarrays L Bubendorf, J Kononen, P Koivisto, P Schraml, H Moch, TC Gasser, ... Cancer research 59 (4), 803-806, 1999 | 895 | 1999 |
Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia HLM Koskela, S Eldfors, P Ellonen, AJ van Adrichem, H Kuusanmäki, ... New England Journal of Medicine 366 (20), 1905-1913, 2012 | 859 | 2012 |
Tissue microarray technology for high-throughput molecular profiling of cancer OP Kallioniemi, U Wagner, J Kononen, G Sauter Human molecular genetics 10 (7), 657-662, 2001 | 857 | 2001 |
Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome M Van De Rijn, CM Perou, R Tibshirani, P Haas, O Kallioniemi, ... The American journal of pathology 161 (6), 1991-1996, 2002 | 795 | 2002 |
Tissue microarrays for rapid linking of molecular changes to clinical endpoints J Torhorst, C Bucher, J Kononen, P Haas, M Zuber, OR Köchli, F Mross, ... The American journal of pathology 159 (6), 2249-2256, 2001 | 772 | 2001 |
A community effort to assess and improve drug sensitivity prediction algorithms JC Costello, LM Heiser, E Georgii, M Gönen, MP Menden, NJ Wang, ... Nature biotechnology 32 (12), 1202-1212, 2014 | 767 | 2014 |
ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization. OP Kallioniemi, A Kallioniemi, W Kurisu, A Thor, LC Chen, HS Smith, ... Proceedings of the National Academy of Sciences 89 (12), 5321-5325, 1992 | 753 | 1992 |
Germline mutations in the ribonuclease L gene in families showing linkage with HPC1 J Carpten, N Nupponen, S Isaacs, R Sood, C Robbins, J Xu, M Faruque, ... Nature genetics 30 (2), 181-184, 2002 | 689 | 2002 |
Tissue microarrays for gene amplification surveys in many different tumor types P Schraml, J Kononen, L Bubendorf, H Moch, H Bissig, A Nocito, ... Clinical Cancer Research 5 (8), 1966-1975, 1999 | 682 | 1999 |
Impact of DNA amplification on gene expression patterns in breast cancer E Hyman, P Kauraniemi, S Hautaniemi, M Wolf, S Mousses, E Rozenblum, ... Cancer research 62 (21), 6240-6245, 2002 | 658 | 2002 |