Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F P Brennan, JW Babbage, BMT Burgering, B Groner, K Reif, DA Cantrell Immunity 7 (5), 679-689, 1997 | 525 | 1997 |
Proteomics analysis of bladder cancer exosomes JL Welton, S Khanna, PJ Giles, P Brennan, IA Brewis, J Staffurth, ... Molecular & Cellular Proteomics 9 (6), 1324-1338, 2010 | 455 | 2010 |
Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers C Pepper, TT Lin, G Pratt, S Hewamana, P Brennan, L Hiller, R Hills, ... Blood 112 (9), 3807-3817, 2008 | 302 | 2008 |
Effects of oxidants and antioxidants on nuclear factor B activation in three different cell lines: evidence against a universal hypothesis involving oxygen radicals P Brennan, LAJ O'Neill Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1260 (2 …, 1995 | 274 | 1995 |
Distinct effects of STAT5 activation on CD4+ and CD8+ T cell homeostasis: development of CD4+ CD25+ regulatory T cells versus CD8+ memory T cells MA Burchill, CA Goetz, M Prlic, JJ O’Neil, IR Harmon, SJ Bensinger, ... The Journal of Immunology 171 (11), 5853-5864, 2003 | 258 | 2003 |
Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation site M Saitoh, N Pullen, P Brennan, D Cantrell, PB Dennis, G Thomas Journal of Biological Chemistry 277 (22), 20104-20112, 2002 | 228 | 2002 |
The NF-κB subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target S Hewamana, S Alghazal, TT Lin, M Clement, C Jenkins, ML Guzman, ... Blood 111 (9), 4681-4689, 2008 | 226 | 2008 |
The NF-kappaB subunit, Rel A, is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukaemia and represents a promising therapeutic target S Hewamana, TT Lin, M Clement, S Alghazal, C Fagan, C Rowntree, ... BRITISH JOURNAL OF HAEMATOLOGY 141, 118-119, 2008 | 226 | 2008 |
Proteomics technologies for the global identification and quantification of proteins IA Brewis, P Brennan Adv Protein Chem Struct Biol 80, 1-44, 2010 | 219 | 2010 |
p70s6k integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes P Brennan, JW Babbage, G Thomas, D Cantrell Molecular and cellular biology 19 (7), 4729-4738, 1999 | 181 | 1999 |
Inhibition of Nuclear Factor [kappa] B by Direct Modification in Whole Cells--Mechanism of Action of Nordihydroguaiaritic Acid, Curcumin and Thiol Modifiers P Brennan, LAJ O'Neill Biochemical pharmacology 55 (7), 965-973, 1998 | 171 | 1998 |
2-mercaptoethanol restores the ability of nuclear factor kappa B (NF kappa B) to bind DNA in nuclear extracts from interleukin 1-treated cells incubated with pyrollidine … P Brennan, LA O'Neill Biochemical Journal 320 (Pt 3), 975, 1996 | 163 | 1996 |
CD38 increases CXCL12-mediated signals and homing of chronic lymphocytic leukemia cells T Vaisitti, S Aydin, D Rossi, F Cottino, L Bergui, G D'Arena, L Bonello, ... Leukemia 24 (5), 958-969, 2010 | 132 | 2010 |
Epstein-Barr virus LMP1 blocks p16INK4a–RB pathway by promoting nuclear export of E2F4/5 N Ohtani, P Brennan, S Gaubatz, E Sanij, P Hertzog, E Wolvetang, ... The Journal of cell biology 162 (2), 173-183, 2003 | 130 | 2003 |
Soluble TLR2 reduces inflammation without compromising bacterial clearance by disrupting TLR2 triggering AC Raby, E Le Bouder, C Colmont, J Davies, P Richards, B Coles, ... The Journal of Immunology 183 (1), 506-517, 2009 | 123 | 2009 |
Reactive oxygen species and mitochondrial sensitivity to oxidative stress determine induction of cancer cell death by p21 I Masgras, S Carrera, PJ de Verdier, P Brennan, A Majid, W Makhtar, ... Journal of Biological Chemistry, 2012 | 121 | 2012 |
A novel Cdk9 inhibitor preferentially targets tumor cells and synergizes with fludarabine E Walsby, G Pratt, H Shao, AY Abbas, PM Fischer, TD Bradshaw, ... Oncotarget 5 (2), 375, 2014 | 94 | 2014 |
Cellular uptake, distribution and cytotoxicity of the hydrophobic cell penetrating peptide sequence PFVYLI linked to the proapoptotic domain peptide PAD CL Watkins, P Brennan, C Fegan, K Takayama, I Nakase, S Futaki, ... Journal of Controlled Release 140 (3), 237-244, 2009 | 91 | 2009 |
Epstein-Barr virus LMP-1 natural sequence variants differ in their potential to activate cellular signaling pathways CA Fielding, K Sandvej, A Mehl, P Brennan, M Jones, M Rowe Journal of virology 75 (19), 9129-9141, 2001 | 88 | 2001 |
LY294002 and rapamycin co‐operate to inhibit T‐cell proliferation EM Breslin, PC White, AM Shore, M Clement, P Brennan British journal of pharmacology 144 (6), 791-800, 2005 | 86 | 2005 |