Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor S Yuzawa, Y Opatowsky, Z Zhang, V Mandiyan, I Lax, J Schlessinger Cell 130 (2), 323-334, 2007 | 433 | 2007 |
Structural analysis of the voltage-dependent calcium channel β subunit functional core and its complex with the α1 interaction domain Y Opatowsky, CC Chen, KP Campbell, JA Hirsch Neuron 42 (3), 387-399, 2004 | 356 | 2004 |
Direct contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling Y Yang, P Xie, Y Opatowsky, J Schlessinger Proceedings of the National Academy of Sciences 107 (5), 1906-1911, 2010 | 112 | 2010 |
Structural basis for SARM1 inhibition and activation under energetic stress M Sporny, J Guez-Haddad, T Khazma, A Yaron, M Dessau, Y Shkolnisky, ... Elife 9, e62021, 2020 | 110 | 2020 |
The voltage-dependent calcium channel β subunit contains two stable interacting domains Y Opatowsky, O Chomsky-Hecht, MG Kang, KP Campbell, JA Hirsch Journal of Biological Chemistry 278 (52), 52323-52332, 2003 | 103 | 2003 |
Structural evidence for an octameric ring arrangement of SARM1 M Sporny, J Guez-Haddad, M Lebendiker, V Ulisse, A Volf, C Mim, ... Journal of Molecular Biology 431 (19), 3591-3605, 2019 | 77 | 2019 |
Structure, domain organization, and different conformational states of stem cell factor-induced intact KIT dimers Y Opatowsky, I Lax, F Tomé, F Bleichert, VM Unger, J Schlessinger Proceedings of the National Academy of Sciences 111 (5), 1772-1777, 2014 | 50 | 2014 |
Structural history of human SRGAP2 proteins M Sporny, J Guez-Haddad, A Kreusch, S Shakartzi, A Neznansky, ... Molecular biology and evolution 34 (6), 1463-1478, 2017 | 46 | 2017 |
Structural principles in Robo activation and auto-inhibition R Barak, G Yom-Tov, J Guez-Haddad, L Gasri-Plotnitsky, R Maimon, ... Cell 177 (2), 272-285. e16, 2019 | 44 | 2019 |
Leukocyte cytoskeleton polarization is initiated by plasma membrane curvature from cell attachment C Ren, Q Yuan, M Braun, X Zhang, B Petri, J Zhang, D Kim, ... Developmental cell 49 (2), 206-219. e7, 2019 | 40 | 2019 |
Ubiquitin-independent proteasomal degradation driven by C-degron pathways Y Makaros, A Raiff, RT Timms, AR Wagh, MI Gueta, A Bekturova, ... Molecular Cell 83 (11), 1921-1935. e7, 2023 | 35 | 2023 |
The Pseudomonas aeruginosa phosphate transport protein PstS plays a phosphate‐independent role in biofilm formation A Neznansky, I Blus‐Kadosh, G Yerushalmi, E Banin, Y Opatowsky The FASEB Journal 28 (12), 5223-5233, 2014 | 33 | 2014 |
Structure–function studies of the G‐domain from human gem, a novel small G‐protein Y Opatowsky, Y Sasson, I Shaked, Y Ward, O Chomsky-Hecht, Y Litvak, ... FEBS letters 580 (25), 5959-5964, 2006 | 33 | 2006 |
The strength and cooperativity of KIT ectodomain contacts determine normal ligand-dependent stimulation or oncogenic activation in cancer AV Reshetnyak, Y Opatowsky, TJ Boggon, E Folta-Stogniew, F Tome, ... Molecular cell 57 (1), 191-201, 2015 | 31 | 2015 |
The neuronal migration factor srGAP2 achieves specificity in ligand binding through a two-component molecular mechanism J Guez-Haddad, M Sporny, Y Sasson, L Gevorkyan-Airapetov, ... Structure 23 (11), 1989-2000, 2015 | 22 | 2015 |
Robo Ig4 is a dimerization domain G Yom-Tov, R Barak, O Matalon, M Barda-Saad, J Guez-Haddad, ... Journal of Molecular Biology 429 (23), 3606-3616, 2017 | 21 | 2017 |
Crystal structure of the extracellular juxtamembrane region of Robo1 R Barak, R Lahmi, L Gevorkyan-Airapetov, E Levy, A Tzur, Y Opatowsky Journal of Structural Biology 186 (2), 283-291, 2014 | 21 | 2014 |
Surface binding inhibitors of the SCF–KIT protein–protein interaction D Margulies, Y Opatowsky, S Fletcher, I Saraogi, LK Tsou, S Saha, I Lax, ... Chembiochem: a European journal of chemical biology 10 (12), 1955, 2009 | 18 | 2009 |
Inhibitors of receptor tyrosine kinases and methods of use thereof J Schlessinger, I Lax, S Yuzawa, Y Opatowsky, Y Yang US Patent 9,273,134, 2016 | 17 | 2016 |
Expression, purification and crystallization of a functional core of the voltage-dependent calcium channel β subunit Y Opatowsky, O Chomsky-Hecht, JA Hirsch Acta Crystallographica Section D: Biological Crystallography 60 (7), 1301-1303, 2004 | 17 | 2004 |