| A CRISPR dropout screen identifies genetic vulnerabilities and therapeutic targets in acute myeloid leukemia K Tzelepis, H Koike-Yusa, E De Braekeleer, Y Li, E Metzakopian, ... Cell reports 17 (4), 1193-1205, 2016 | 697 | 2016 |
| ArrayExpress update—trends in database growth and links to data analysis tools G Rustici, N Kolesnikov, M Brandizi, T Burdett, M Dylag, I Emam, A Farne, ... Nucleic acids research 41 (D1), D987-D990, 2012 | 434 | 2012 |
| Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: implications for 22q11 deletion syndrome R Paylor, B Glaser, A Mupo, P Ataliotis, C Spencer, A Sobotka, C Sparks, ... Proceedings of the National Academy of Sciences 103 (20), 7729-7734, 2006 | 356 | 2006 |
| Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia MWM Kühn, E Song, Z Feng, A Sinha, CW Chen, AJ Deshpande, ... Cancer discovery 6 (10), 1166-1181, 2016 | 249 | 2016 |
| Hemopoietic-specific Sf3b1-K700E knock-in mice display the splicing defect seen in human MDS but develop anemia without ring sideroblasts A Mupo, M Seiler, V Sathiaseelan, A Pance, Y Yang, AA Agrawal, F Iorio, ... Leukemia 31 (3), 720-727, 2017 | 145 | 2017 |
| A powerful molecular synergy between mutant Nucleophosmin and Flt3-ITD drives acute myeloid leukemia in mice A Mupo, L Celani, O Dovey, JL Cooper, C Grove, R Rad, P Sportoletti, ... Leukemia 27 (9), 1917-1920, 2013 | 106 | 2013 |
| Exploring death receptor pathways as selective targets in cancer therapy M Russo, A Mupo, C Spagnuolo, GL Russo Biochemical pharmacology 80 (5), 674-682, 2010 | 96 | 2010 |
| Synergistic targeting of FLT3 mutations in AML via combined menin-MLL and FLT3 inhibition MM Dzama, M Steiner, J Rausch, D Sasca, J Schönfeld, K Kunz, ... Blood, The Journal of the American Society of Hematology 136 (21), 2442-2456, 2020 | 91 | 2020 |
| Flavonoid quercetin sensitizes a CD95-resistant cell line to apoptosis by activating protein kinase Cα M Russo, R Palumbo, A Mupo, M Tosto, G Iacomino, A Scognamiglio, ... Oncogene 22 (21), 3330-3342, 2003 | 84 | 2003 |
| Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia OM Dovey, JL Cooper, A Mupo, CS Grove, C Lynn, N Conte, RM Andrews, ... Blood, The Journal of the American Society of Hematology 130 (17), 1911-1922, 2017 | 79 | 2017 |
| Tbx1 regulates Vegfr3 and is required for lymphatic vessel development L Chen, A Mupo, T Huynh, S Cioffi, M Woods, C Jin, W McKeehan, ... Journal of Cell Biology 189 (3), 417-424, 2010 | 75 | 2010 |
| Genetic modification of primary human B cells to model high-grade lymphoma R Caeser, M Di Re, JA Krupka, J Gao, M Lara-Chica, JML Dias, SL Cooke, ... Nature Communications 10 (1), 4543, 2019 | 70 | 2019 |
| Quercetin induced apoptosis in association with death receptors and fludarabine in cells isolated from chronic lymphocytic leukaemia patients M Russo, C Spagnuolo, S Volpe, A Mupo, I Tedesco, GL Russo British journal of cancer 103 (5), 642-648, 2010 | 64 | 2010 |
| Mouse models of NPM1-mutated acute myeloid leukemia: biological and clinical implications P Sportoletti, E Varasano, R Rossi, A Mupo, E Tiacci, G Vassiliou, ... Leukemia 29 (2), 269-278, 2015 | 53 | 2015 |
| Fgf8 expression in the Tbx1 domain causes skeletal abnormalities and modifies the aortic arch but not the outflow tract phenotype of Tbx1 mutants F Vitelli, Z Zhang, T Huynh, A Sobotka, A Mupo, A Baldini Developmental biology 295 (2), 559-570, 2006 | 52 | 2006 |
| Vitamin D receptor controls cell stemness in acute myeloid leukemia and in normal bone marrow E Paubelle, F Zylbersztejn, TT Maciel, C Carvalho, A Mupo, M Cheok, ... Cell reports 30 (3), 739-754. e4, 2020 | 39 | 2020 |
| Mutational synergy during leukemia induction remodels chromatin accessibility, histone modifications and three-dimensional DNA topology to alter gene expression H Yun, N Narayan, S Vohra, G Giotopoulos, A Mupo, P Madrigal, D Sasca, ... Nature genetics 53 (10), 1443-1455, 2021 | 29 | 2021 |
| A CRISPR dropout screen identifies genetic vulnerabilities and therapeutic targets in acute myeloid leukemia. Cell Rep. 17, 1193–1205 K Tzelepis, H Koike-Yusa, E De Braekeleer, Y Li, E Metzakopian, ... J. CELREP 79, 2016 | 18 | 2016 |
| Biochemical and functional characterization of protein kinase CK2 in ascidian Ciona intestinalis oocytes at fertilization: Cloning and sequence analysis of cDNA for α and β … GL Russo, M Tosto, A Mupo, I Castellano, A Cuomo, E Tosti Journal of Biological Chemistry 279 (31), 33012-33023, 2004 | 18 | 2004 |
| Targeting chromatin regulators inhibits leukemogenic gene expression in NPM1 mutant leukemia. Cancer Discov. 2016; 6: 1166–1181. doi: 10.1158/2159-8290 MWM Kühn, E Song, Z Feng, A Sinha, CW Chen, AJ Deshpande, ... CD-16-0237.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 11 | |
