Potently neutralizing and protective human antibodies against SARS-CoV-2 SJ Zost, P Gilchuk, JB Case, E Binshtein, RE Chen, JP Nkolola, A Schäfer, ... Nature 584 (7821), 443-449, 2020 | 1128 | 2020 |
Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition AJ Greaney, TN Starr, P Gilchuk, SJ Zost, E Binshtein, AN Loes, SK Hilton, ... Cell host & microbe 29 (1), 44-57. e9, 2021 | 1076 | 2021 |
Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies RE Chen, X Zhang, JB Case, ES Winkler, Y Liu, LA VanBlargan, J Liu, ... Nature medicine 27 (4), 717-726, 2021 | 963 | 2021 |
Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein SJ Zost, P Gilchuk, RE Chen, JB Case, JX Reidy, A Trivette, RS Nargi, ... Nature medicine 26 (9), 1422-1427, 2020 | 474 | 2020 |
Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein N Suryadevara, S Shrihari, P Gilchuk, LA VanBlargan, E Binshtein, ... Cell 184 (9), 2316-2331. e15, 2021 | 375 | 2021 |
Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection ES Winkler, P Gilchuk, J Yu, AL Bailey, RE Chen, Z Chong, SJ Zost, ... Cell 184 (7), 1804-1820. e16, 2021 | 324 | 2021 |
High frequency of shared clonotypes in human B cell receptor repertoires C Soto, RG Bombardi, A Branchizio, N Kose, P Matta, AM Sevy, ... Nature 566 (7744), 398-402, 2019 | 279 | 2019 |
Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail J Dong, SJ Zost, AJ Greaney, TN Starr, AS Dingens, EC Chen, RE Chen, ... Nature microbiology 6 (10), 1233-1244, 2021 | 262 | 2021 |
In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains RE Chen, ES Winkler, JB Case, ID Aziati, TL Bricker, A Joshi, TL Darling, ... Nature 596 (7870), 103-108, 2021 | 220 | 2021 |
A site of vulnerability on the influenza virus hemagglutinin head domain trimer interface S Bangaru, S Lang, M Schotsaert, HA Vanderven, X Zhu, N Kose, ... Cell 177 (5), 1136-1152. e18, 2019 | 206 | 2019 |
Viral acute lower respiratory infections impair CD8+ T cells through PD-1 JJ Erickson, P Gilchuk, AK Hastings, SJ Tollefson, M Johnson, ... The Journal of clinical investigation 122 (8), 2967-2982, 2012 | 193 | 2012 |
Cross-neutralizing and protective human antibody specificities to poxvirus infections I Gilchuk, P Gilchuk, G Sapparapu, R Lampley, V Singh, N Kose, DL Blum, ... Cell 167 (3), 684-694. e9, 2016 | 174 | 2016 |
Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell M Puray-Chavez, KM LaPak, TP Schrank, JL Elliott, DP Bhatt, ... Cell Reports 36 (2), 2021 | 135 | 2021 |
Genetic and structural basis for recognition of SARS-CoV-2 spike protein by a two-antibody cocktail J Dong, SJ Zost, AJ Greaney, TN Starr, AS Dingens, EC Chen, RE Chen, ... BioRxiv, 2021.01. 27.428529, 2021 | 123 | 2021 |
Mucosal Immunization with a pH-Responsive Nanoparticle Vaccine Induces Protective CD8+ Lung-Resident Memory T Cells FC Knight, P Gilchuk, A Kumar, KW Becker, S Sevimli, ME Jacobson, ... ACS nano 13 (10), 10939-10960, 2019 | 102 | 2019 |
A novel pre-fusion conformation-specific neutralizing epitope on the respiratory syncytial virus fusion protein JJ Mousa, N Kose, P Matta, P Gilchuk, JE Crowe Nature microbiology 2 (4), 1-8, 2017 | 98 | 2017 |
Poly (propylacrylic acid)-peptide nanoplexes as a platform for enhancing the immunogenicity of neoantigen cancer vaccines F Qiu, KW Becker, FC Knight, JJ Baljon, S Sevimli, D Shae, P Gilchuk, ... Biomaterials 182, 82-91, 2018 | 90 | 2018 |
Antibody-dependent enhancement of Ebola virus infection by human antibodies isolated from survivors NA Kuzmina, P Younan, P Gilchuk, RI Santos, AI Flyak, PA Ilinykh, ... Cell reports 24 (7), 1802-1815. e5, 2018 | 90 | 2018 |
A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope LA VanBlargan, LJ Adams, Z Liu, RE Chen, P Gilchuk, S Raju, BK Smith, ... Immunity 54 (10), 2399-2416. e6, 2021 | 85 | 2021 |
Analysis of a therapeutic antibody cocktail reveals determinants for cooperative and broad ebolavirus neutralization P Gilchuk, CD Murin, JC Milligan, RW Cross, CE Mire, PA Ilinykh, ... Immunity 52 (2), 388-403. e12, 2020 | 82 | 2020 |