| Comparative mitochondrial-based protective effects of resveratrol and nicotinamide in Huntington’s disease models L Naia, TR Rosenstock, AM Oliveira, SI Oliveira-Sousa, GL Caldeira, ... Molecular neurobiology 54 (7), 5385-5399, 2017 | 123 | 2017 |
| Activation of IGF-1 and insulin signaling pathways ameliorate mitochondrial function and energy metabolism in Huntington’s Disease human lymphoblasts L Naia, IL Ferreira, T Cunha-Oliveira, AI Duarte, M Ribeiro, ... Molecular neurobiology 51, 331-348, 2015 | 80 | 2015 |
| Cellular turnover of the polyglutamine disease protein ataxin-3 is regulated by its catalytic activity SV Todi, MN Laco, BJ Winborn, SM Travis, HM Wen, HL Paulson Journal of Biological Chemistry 282 (40), 29348-29358, 2007 | 69 | 2007 |
| Compromised mitochondrial complex II in models of Machado–Joseph disease MN Laço, CR Oliveira, HL Paulson, AC Rego Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1822 (2), 139-149, 2012 | 68 | 2012 |
| Mitochondrial respiratory chain complex activity and bioenergetic alterations in human platelets derived from pre-symptomatic and symptomatic Huntington's disease carriers AC Silva, S Almeida, M Laço, AI Duarte, J Domingues, CR Oliveira, ... Mitochondrion 13 (6), 801-809, 2013 | 50 | 2013 |
| BDNF regulates BIM expression levels in 3-nitropropionic acid-treated cortical neurons S Almeida, M Laço, T Cunha-Oliveira, CR Oliveira, AC Rego Neurobiology of disease 35 (3), 448-456, 2009 | 42 | 2009 |
| Valosin-containing protein (VCP/p97) is an activator of wild-type ataxin-3 MN Laço, L Cortes, SM Travis, HL Paulson, AC Rego Public Library of Science 7 (9), e43563, 2012 | 36 | 2012 |
| A whole brain longitudinal study in the YAC128 mouse model of Huntington’s disease shows distinct trajectories of neurochemical, structural connectivity and volumetric changes LI Petrella, JM Castelhano, M Ribeiro, JV Sereno, SI Goncalves, MN Laco, ... Human molecular genetics 27 (12), 2125-2137, 2018 | 27 | 2018 |
| Dysregulation of CREB activation and histone acetylation in 3-nitropropionic acid-treated cortical neurons: prevention by BDNF and NGF S Almeida, T Cunha-Oliveira, M Laço, CR Oliveira, AC Rego Neurotoxicity research 17, 399-405, 2010 | 24 | 2010 |
| Expression of NR1/NR2B NMethyldAspartate Receptors Enhances Heroin Toxicity in HEK293 Cells A Domingues, T Cunha Oliveira, MLN Laço, TRA Macedo, CR Oliveira, ... Annals of the New York Academy of Sciences 1074 (1), 458-465, 2006 | 20 | 2006 |
| Mitochondrial and redox modifications in early stages of Huntington's disease C Lopes, IL Ferreira, C Maranga, M Beatriz, SI Mota, J Sereno, ... Redox biology 56, 102424, 2022 | 17 | 2022 |
| Expanded and wild-type Ataxin-3 modify the redox status of SH-SY5Y cells overexpressing α-synuclein C Noronha, R Perfeito, M Laço, U Wüllner, AC Rego Neurochemical research 42, 1430-1437, 2017 | 9 | 2017 |
| Clinically Relevant KCNQ1 Variants Causing KCNQ1-KCNE2 Gain-of-Function Affect the Ca2+ Sensitivity of the Channel CK Bauer, T Holling, D Horn, MN Laço, E Abdalla, OM Omar, M Alawi, ... International Journal of Molecular Sciences 23 (17), 9690, 2022 | 1 | 2022 |
| Overreduced intracellular state detected in Cu-ATSM brain imaging and fibroblasts from prodromal Huntington disease carriers C Lopes, J Castelhano, M Beatriz, C Fernandes, M Laco, C Januario, ... EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 50, 27-28, 2020 | | 2020 |
| Increasesd brain levels of hydrogen peroxide in a transgenic mouse model of Huntington's disease MLN Laço | | 2015 |
| 3rd International Conference and Exhibition on Neurology & Therapeutics TR Rosenstock, L Naia, SI Oliveira-Sousa, A Oliveira, GL Caldeira, ... | | 2014 |
| Sirtuin modulators alter mitochondrial function in in vitro and in vivo Huntington's disease models L Naia, TR Rosenstock, SI Oliveira-Sousa, GL Caldeira, MN Laco, ... EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 43, 44-44, 2013 | | 2013 |
| Studies on the Activity of Ataxin-3 and Miyochondrial Dysfunction in Models of Machado-Joseph Disease MN Laço PQDT-Global, 2012 | | 2012 |
| Mitochondrial inhibition in cell models of Machado-Joseph disease. MN Laco, CR Oliveira, HL Paulson, AC Rego | | |
