A role for polyproline motifs in the spinal muscular atrophy protein SMN: profilins bind to and colocalize with SMN in nuclear gems T Giesemann, S Rathke-Hartlieb, M Rothkegel, JW Bartsch, S Buchmeier, ... Journal of Biological Chemistry 274 (53), 37908-37914, 1999 | 286 | 1999 |
The metalloprotease disintegrin ADAM8: processing by autocatalysis is required for proteolytic activity and cell adhesion U Schlomann, D Wildeboer, A Webster, O Antropova, D Zeuschner, ... Journal of biological chemistry 277 (50), 48210-48219, 2002 | 226 | 2002 |
Metalloproteinase disintegrins ADAM8 and ADAM19 are highly regulated in human primary brain tumors and their expression levels and activities are associated with invasiveness D Wildeboer, S Naus, QXA Sang, JW Bartsch, A Pagenstecher Journal of Neuropathology & Experimental Neurology 65 (5), 516-527, 2006 | 207 | 2006 |
The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events ML Moss, M Bomar, Q Liu, H Sage, P Dempsey, PM Lenhart, PA Gillispie, ... Journal of Biological Chemistry 282 (49), 35712-35721, 2007 | 202 | 2007 |
The immune microenvironment in pancreatic cancer M Huber, CU Brehm, TM Gress, M Buchholz, B Alashkar Alhamwe, ... International journal of molecular sciences 21 (19), 7307, 2020 | 192 | 2020 |
Tumor necrosis factor α induces a metalloprotease-disintegrin, ADAM8 (CD 156): implications for neuron–glia interactions during neurodegeneration U Schlomann, S Rathke-Hartlieb, S Yamamoto, H Jockusch, JW Bartsch Journal of Neuroscience 20 (21), 7964-7971, 2000 | 187 | 2000 |
The prokaryotic neomycin-resistance-encoding gene acts as a transcriptional silencer in eukaryotic cells P Artelt, R Grannemann, C Stocking, J Friel, J Bartsch, H Hauser Gene 99 (2), 249-254, 1991 | 184 | 1991 |
Use of a novel collagen matrix with oriented pore structure for muscle cell differentiation in cell culture and in grafts V Kroehne, I Heschel, F Schügner, D Lasrich, JW Bartsch, H Jockusch Journal of cellular and molecular medicine 12 (5a), 1640-1648, 2008 | 182 | 2008 |
Therapeutic benefits from targeting of ADAM family members ML Moss, JW Bartsch Biochemistry 43 (23), 7227-7235, 2004 | 165 | 2004 |
Ectodomain shedding of the neural recognition molecule CHL1 by the metalloprotease-disintegrin ADAM8 promotes neurite outgrowth and suppresses neuronal cell death S Naus, M Richter, D Wildeboer, M Moss, M Schachner, JW Bartsch Journal of Biological Chemistry 279 (16), 16083-16090, 2004 | 160 | 2004 |
ADAM8 as a drug target in pancreatic cancer U Schlomann, G Koller, C Conrad, T Ferdous, P Golfi, AM Garcia, ... Nature communications 6 (1), 6175, 2015 | 153 | 2015 |
Shedding of endogenous interleukin-6 receptor (IL-6R) is governed by a disintegrin and metalloproteinase (ADAM) proteases while a full-length IL-6R isoform localizes to … N Schumacher, D Meyer, A Mauermann, J von der Heyde, J Wolf, ... Journal of Biological Chemistry 290 (43), 26059-26071, 2015 | 152 | 2015 |
Metalloprotease‐disintegrin ADAM8: expression analysis and targeted deletion in mice K Kelly, G Hutchinson, D Nebenius‐Oosthuizen, AJH Smith, JW Bartsch, ... Developmental dynamics: an official publication of the American Association …, 2005 | 141 | 2005 |
A functional knock-out of titin results in defective myofibril assembly PFM van der Ven, JW Bartsch, M Gautel, H Jockusch, DO Fürst Journal of Cell Science 113 (8), 1405-1414, 2000 | 140 | 2000 |
Effects of MMP inhibitors incorporated within dental adhesives A Almahdy, G Koller, S Sauro, JW Bartsch, M Sherriff, TF Watson, ... Journal of dental research 91 (6), 605-611, 2012 | 126 | 2012 |
Moderate increase in histone acetylation activates the mouse mammary tumor virus promoter and remodels its nucleosome structure. J Bartsch, M Truss, J Bode, M Beato Proceedings of the National Academy of Sciences 93 (20), 10741-10746, 1996 | 124 | 1996 |
Essential roles of telomerase reverse transcriptase hTERT in cancer stemness and metastasis R Hannen, JW Bartsch FEBS letters 592 (12), 2023-2031, 2018 | 116 | 2018 |
ADAM 8 expression in invasive breast cancer promotes tumor dissemination and metastasis M Romagnoli, ND Mineva, M Polmear, C Conrad, S Srinivasan, ... EMBO molecular medicine 6 (2), 278-294, 2014 | 115 | 2014 |
Identification of candidate substrates for ectodomain shedding by the metalloprotease-disintegrin ADAM8 S Naus, S Reipschläger, D Wildeboer, SF Lichtenthaler, S Mitterreiter, ... Walter de Gruyter 387 (3), 337-346, 2006 | 112 | 2006 |
Tumor necrosis factor-α (TNF-α) regulates shedding of TNF-α receptor 1 by the metalloprotease-disintegrin ADAM8: evidence for a protease-regulated feedback loop in neuroprotection JW Bartsch, D Wildeboer, G Koller, S Naus, A Rittger, ML Moss, Y Minai, ... Journal of Neuroscience 30 (36), 12210-12218, 2010 | 94 | 2010 |