Mutual paracrine effects of oral squamous cell carcinoma cells and normal oral fibroblasts: induction of fibroblast to myofibroblast transdifferentiation and modulation of … MG Kellermann, LM Sobral, SD da Silva, KG Zecchin, E Graner, ... Oral oncology 44 (5), 509-517, 2008 | 197 | 2008 |
Fatty acid synthase inhibition with Orlistat promotes apoptosis and reduces cell growth and lymph node metastasis in a mouse melanoma model MA Carvalho, KG Zecchin, F Seguin, DC Bastos, M Agostini, ... International journal of cancer 123 (11), 2557-2565, 2008 | 194 | 2008 |
Myofibroblasts in the stroma of oral squamous cell carcinoma are associated with poor prognosis MG Kellermann, LM Sobral, SD Silva, KG Zecchin, E Graner, MA Lopes, ... Histopathology 51 (6), 849-853, 2007 | 176 | 2007 |
The fatty acid synthase inhibitor orlistat reduces experimental metastases and angiogenesis in B16-F10 melanomas F Seguin, MA Carvalho, DC Bastos, M Agostini, KG Zecchin, ... British journal of cancer 107 (6), 977-987, 2012 | 156 | 2012 |
The fatty acid synthase inhibitor orlistat reduces the growth and metastasis of orthotopic tongue oral squamous cell carcinomas M Agostini, LY Almeida, DC Bastos, RM Ortega, FS Moreira, F Seguin, ... Molecular cancer therapeutics 13 (3), 585-595, 2014 | 129 | 2014 |
Overexpression of HOXB7 homeobox gene in oral cancer induces cellular proliferation and is associated with poor prognosis MF De Souza Setubal Destro, CC Bitu, KG Zecchin, E Graner, MA Lopes, ... International journal of oncology 36 (1), 141-149, 2010 | 100 | 2010 |
Inhibition of fatty acid synthase in melanoma cells activates the intrinsic pathway of apoptosis KG Zecchin, FA Rossato, HF Raposo, DR Melo, LC Alberici, HCF Oliveira, ... Laboratory investigation 91 (2), 232-240, 2011 | 78 | 2011 |
Defective insulin and acetylcholine induction of endothelial cell–nitric oxide synthase through insulin receptor substrate/Akt signaling pathway in aorta of obese rats HG Zecchin, FBM Priviero, CT Souza, KG Zecchin, PO Prada, ... Diabetes 56 (4), 1014-1024, 2007 | 78 | 2007 |
Fatty acid synthase is required for the proliferation of human oral squamous carcinoma cells M Agostini, SD Silva, KG Zecchin, RD Coletta, J Jorge, M Loda, E Graner Oral oncology 40 (7), 728-735, 2004 | 78 | 2004 |
A central role for neuronal adenosine 5′-monophosphate-activated protein kinase in cancer-induced anorexia ER Ropelle, JR Pauli, KG Zecchin, M Ueno, CT de Souza, J Morari, ... Endocrinology 148 (11), 5220-5229, 2007 | 60 | 2007 |
Smad7 blocks transforming growth factor‐β1–induced gingival fibroblast–myofibroblast transition via inhibitory regulation of smad2 and connective tissue growth factor LM Sobral, PF Montan, KG Zecchin, H Martelli‐Junior, PA Vargas, ... Journal of Periodontology 82 (4), 642-651, 2011 | 49 | 2011 |
Fatty acid synthase inhibitors induce apoptosis in non-tumorigenic melan-a cells associated with inhibition of mitochondrial respiration FA Rossato, KG Zecchin, PG La Guardia, RM Ortega, LC Alberici, ... PLoS One 9 (6), e101060, 2014 | 45 | 2014 |
Heterogeneous presence of myofibroblasts in hereditary gingival fibromatosis CC Bitu, LM Sobral, MG Kellermann, H Martelli‐Junior, KG Zecchin, ... Journal of clinical periodontology 33 (6), 393-400, 2006 | 45 | 2006 |
Ovariectomy delays alveolar wound healing after molar extractions in rats MC Pereira, KG Zecchin, EB Campagnoli, J Jorge Journal of oral and maxillofacial surgery 65 (11), 2248-2253, 2007 | 44 | 2007 |
Simvastatin inducing PC3 prostate cancer cell necrosis mediated by calcineurin and mitochondrial dysfunction KAP Oliveira, KG Zecchin, LC Alberici, RF Castilho, AE Vercesi Journal of bioenergetics and biomembranes 40, 307-314, 2008 | 43 | 2008 |
Mitochondrial ATP-sensitive K+ channels as redox signals to liver mitochondria in response to hypertriglyceridemia LC Alberici, HCF Oliveira, BA Paim, CC Mantello, AC Augusto, ... Free Radical Biology and Medicine 47 (10), 1432-1439, 2009 | 42 | 2009 |
Cramoll 1, 4 lectin increases ROS production, calcium levels, and cytokine expression in treated spleen cells of rats CML de Melo, BA Paim, KG Zecchin, J Morari, MR Chiaratti, MTS Correia, ... Molecular and cellular biochemistry 342, 163-169, 2010 | 41 | 2010 |
Serum-starved apoptotic fibroblasts reduce blastocyst production but enable development to term after SCNT in cattle MS Miranda, FF Bressan, KG Zecchin, AE Vercesi, LG Mesquita, ... Cloning and stem cells 11 (4), 565-573, 2009 | 40 | 2009 |
Ovariectomy reduces the gelatinolytic activity and expression of matrix metalloproteinases and collagen in rat molar extraction wounds KG Zecchin, MC Pereira, RD Coletta, E Graner, J Jorge Calcified tissue international 76, 136-145, 2005 | 35 | 2005 |
Role of mitochondria in the immune response to cancer: a central role for Ca2+ GR Degasperi, JA Velho, KG Zecchin, CT Souza, LA Velloso, J Borecký, ... Journal of bioenergetics and biomembranes 38, 1-10, 2006 | 33 | 2006 |